Cleveland Guardians vs Chicago White Sox Prediction for 7/13/2025 MLB Picks, Best Bets & Odds

Home » Cleveland Guardians vs Chicago White Sox Prediction for 7/13/2025 MLB Picks, Best Bets & Odds

Game: Cleveland Guardians vs. Chicago White Sox

Date: Sunday, July 13, 2025

Location: Rate Field, Chicago, IL

Broadcast: Chicago Sports Network

Odds/Point Spread: Cleveland (-122) Chicago (+102)

The Cleveland Guardians (43-48) will clash with the Chicago White Sox (31-62) at Rate Field this Sunday. The betting odds place the Guardians at -122 and the White Sox at +102, with a total set at 9 runs. The starting pitchers for this matchup are Joey Cantillo and Aaron Civale.

MLB predictions for Cleveland Guardians by David Fry

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Cleveland’s current slugging percentage stands at .366, with hitters striking out 744 times and receiving 281 walks. The team has recorded 318 RBIs alongside 665 hits, yielding a batting average of .224. The Guardians have achieved 128 doubles and 92 home runs this season, totaling 333 runs and an on-base percentage (OBP) of .295. Collectively, they average 3.7 runs per game, placing them 26th in Major League Baseball (MLB).

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The Guardians boast a team ERA of 3.97 this season, ranking 18th in MLB, with pitchers registering 767 strikeouts. They have allowed 95 home runs and 384 runs (15th in the league). The staff has issued 335 walks, contributing to a collective FIP of 4.08. Cleveland has given up 756 hits, averaging 8.5 hits per nine innings, and they carry a K/BB ratio of 2.29 with a WHIP of 1.36.

This season, the Guardians have utilized 306 relief pitchers, with relief efforts resulting in 38.4% of inherited runners scoring. To date, they have secured 25 saves but have missed out on 10 of 35 save opportunities, giving them a save percentage of 71.4%. Their bullpen ranks 4th in the league with 64 holds and has faced 100 save situations. Guardians relievers have entered games with runners on base 79 times and have made 95 high-leverage appearances.

The Guardians have achieved a 68.5% conversion rate of balls in play into outs over their 7,245 innings, landing them 24th in the league. The Cincinnati Reds have registered 2,415 putouts along with 730 assists and 65 errors this season. With a fielding percentage of .980, they rank 28th in MLB and have turned 69 double plays.

Cantillo has logged 73 innings in his professional career, striking out 92 batters. With a record of 3-4, he faces 321 batters with a FIP of 4.35. His ERA is at 4.41, allowing 36 earned runs, and he owns a WHIP of 1.390, having given up 67 hits (8.2 hits per 9 innings) along with 35 walks.

The White Sox exhibit a team slugging percentage of .345, averaging 3.42 runs per game (28th in MLB). With 142 doubles, they have walked 301 times along with tallying 318 runs. This season, Chicago has 71 home runs and 303 RBIs, resulting in 794 strikeouts (ranked 12th in MLB) and 672 total hits. Their on-base percentage is .296, and their batting average stands at .222.

Chicago’s pitching staff has given up 410 runs this year, maintaining a team ERA of 4.14 (with 370 earned runs allowed). They have conceded 100 home runs and allow 4.59 runs per nine innings (22nd in the league). The team holds a WHIP of 1.396, with a FIP of 4.52. Their strikeout to walk ratio this season is 7.40 (659 strikeouts against 338 walks), ranking them 21st in MLB for total hits allowed at 785.

Chicago’s relievers have been called upon in 27 save opportunities and secured 12 saves, positioning them at 30th in MLB with a save percentage of 44.4%. They have deployed 287 relief pitchers this season. Their relief pitchers have made 82 high-leverage appearances and addressed 83 situations with runners on base, with 28.9% of inherited runners scoring. The White Sox have recorded 69 save situations so far, tallying 42 holds and 15 blown saves.

This season, the Chicago White Sox have achieved 80 double plays and maintain a fielding percentage of .983 (26th in MLB). They’ve recorded 768 assists, 56 errors, and have achieved 2,414 putouts across 7,242 innings, presenting a defensive efficiency of 69.5% (18th in professional baseball).

Civale has allowed 647 hits throughout his career, achieving 610 strikeouts over 683 innings pitched. He has accumulated a total of 312 earned runs with a WHIP of 1.225 and a FIP of 4.0. Civale’s K/BB ratio is 3.21, having faced 2,850 hitters in MLB. With a career record of 40-41, he boasts an ERA of 4.11 and typically allows 8.5 hits per nine innings.

Who will emerge victorious in tonight’s MLB matchup against the spread or moneyline?

Guy Bruhn’s Prediction: Choose Chicago (+102)

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