- Matchup: Arizona Diamondbacks vs San Diego Padres
- Date: Friday, September 26, 2025
- Venue: Petco Park, San Diego, CA
- Broadcast: Padres.TV
- Betting Odds: Arizona (+120), San Diego (-144)
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The San Diego Padres (87-72) will clash with the Arizona Diamondbacks (80-78) at Petco Park this Friday. The current moneyline places the Diamondbacks at +120, while the Padres are at -144. The over/under for the game is set at 8 runs. Zac Gallen and Yu Darvish are projected to take the mound as starting pitchers.

The Arizona Diamondbacks have been impressive, averaging 5.0 runs per game, which places them 4th in the MLB rankings. They have scored a total of 782 runs this season with an on-base percentage of .325. The team has registered 271 doubles and 210 home runs, along with 761 runs batted in, accumulating 1,348 hits and a batting average of .252. Their slugging percentage stands at .434, though they have struck out 1,271 times while walking 527 times.
The Diamondbacks’ strikeout-to-walk ratio is 2.59, and the pitching staff has a combined WHIP of 1.31. Arizona’s pitchers have allowed 187 home runs and a total of 753 runs scored, placing them at 23rd in the league. They’ve given up 1,362 hits this season (8.7 hits per 9 innings) and 693 earned runs, resulting in a team ERA of 4.42, also ranked 23rd in the majors. The staff has amassed 1,254 strikeouts this season while walking 485 batters, with a collective FIP of 4.24.
Diamondbacks pitchers have entered games with base runners 146 times and made 164 high-leverage appearances. The bullpen has recorded 88 holds, ranking 14th in the league. With a save percentage of 59.2%, they have entered 164 save situations, achieving 42 saves but failing to convert on 29 of 71 chances. This season, 192 base runners have been inherited, with 33.3% scoring. The team has used 489 relief pitchers to date.
Arizona converts 69.6% of batted balls into outs across 12,699 innings, ranking them 20th in the league. So far, they have achieved 4,233 putouts, 1,412 assists, and made 80 errors, securing a fielding percentage of .986, good for 16th place overall, alongside 125 double plays.
Zac Gallen has pitched 1,002 innings with 1,057 strikeouts in his career. Holding a career record of 66-51, Gallen’s FIP is 3.50 with an ERA of 3.56 (396 earned runs allowed) and a WHIP of 1.154. He has allowed 836 hits, averaging 7.5 hits per 9 innings, along with striking out 321 batters.
On the other side, the Padres have a team slugging percentage of .388 and score an average of 4.26 runs per game (19th in MLB). They have recorded 248 doubles, taken 499 walks, and scored a total of 678 runs with 147 home runs and 639 RBIs. However, they have struck out 1,137 times (28th in baseball) and accumulated 1,339 hits. The San Diego Padres have a season OBP of .320 as well as a batting average of .252.
The Padres hold a team WHIP of 1.203 and a FIP of 4.01 this season. Their strikeout-to-walk ratio stands at 8.90 (with 1,392 strikeouts and 519 walks). They are ranked 1st in the league for fewest hits allowed, with a total of 1,173. They’ve surrendered 174 home runs and allow 3.92 runs per 9 innings (2nd best in MLB), with a team ERA of 3.64 on the season (569 earned runs given up).
San Diego’s bullpen has an inherited scoring rate of 29.4% for 255 inherited runners. The relievers have faced high-pressure situations 208 times and dealt with base runners in 181 of those appearances. They have worked through 172 save opportunities, compiling 103 holds and recording 16 blown saves. Currently, they lead the league with a 75.0% save percentage, having used 564 relief pitchers this season and notching 48 saves.
In terms of defense, the Padres have turned 114 double plays and maintain a fielding percentage of .987 (10th in MLB). They boast 1,208 assists, 73 errors, and a total of 4,218 putouts over 12,654 innings, showcasing a defensive efficiency of 71.8% (3rd among MLB teams).
Yu Darvish has allowed 1,454 hits during his career and has tallied 2,071 strikeouts in 1,773 innings pitched. His career record stands at 114-93, with an ERA of 3.65, yielding 7.4 hits per nine innings. Darvish has given up 719 earned runs, has a WHIP of 1.136, and a FIP of 3.6. His strikeout-to-walk ratio is 3.69, having faced 7,285 opposing batters so far.
Which team will emerge victorious in this MLB matchup tonight?
Prediction: Back San Diego (-144)
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