Matchup: Bowling Green Falcons vs. Louisville Cardinals
Game Date: Saturday, September 20, 2025
Venue: L&N Federal Credit Union Stadium, Louisville, KY
Broadcast: ACC Network
Betting Odds/Point Spread: Cardinals favored by 26.5 points
Over/Under Total: 51.5
On Saturday, September 20, 2025, the Louisville Cardinals (2-0) will face off against the Bowling Green Falcons (2-1) at the L&N Federal Credit Union Stadium. The Cardinals are set as 26.5-point favorites, with the over/under total established at 51.5.
The Bowling Green Falcons enter this matchup with a record of 2-1 for the season. In their most recent game, they triumphed over the Liberty Flames with a score of 23-13. The Falcons executed 36 rushing attempts, accumulating 158 yards, averaging 4.4 yards per carry. Overall, they ran 68 plays, tallying 304 yards. Defensively, Bowling Green permitted 13 completions on 25 attempts for 194 yards, resulting in a 52.0% completion rate. In the running department, they allowed 152 yards on 39 attempts, equating to 3.9 yards per rush.

Regarding scoring, the Falcons average 23.0 points per game. Their rushing performance yields an average of 137.7 yards, ranking 89th in Division 1. This season, Bowling Green has amassed 942 total yards, scoring 2 touchdowns through the air and 3 on the ground. As a unit, they have achieved 55 first downs and incurred 21 penalties totaling 171 yards. Importantly, they have yet to turn the ball over.
Defensively against the pass, Bowling Green has allowed 645 yards, positioning them 82nd nationally. They give up an average of 215.0 yards per game through the air, allowing a completion rate of 58.8%. Overall, they have conceded an average of 320.7 yards per game, ranking 60th in the nation. They have surrendered 5 passing touchdowns and 2 rushing touchdowns, yielding an average of 3.2 yards per carry and 105.7 rushing yards per game. Currently, they rank 47th in college football in team defense, allowing 18.0 points per game.
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The Louisville Cardinals bring a 2-0 record into this encounter. In their latest outing, they secured a 28-14 victory over the James Madison Dukes. Louisville averaged 3.8 yards per carry, finishing the game with 113 yards on 30 attempts. Overall, they achieved 264 yards across 53 plays, averaging 5.0 yards per play. On the defensive side, Louisville’s pass defense allowed a completion rate of 58.1%, yielding 137 yards on 18 completions out of 31 attempts. They allowed 47 rushing attempts for 126 yards, averaging 2.7 yards per carry.

In terms of scoring, the Cardinals rank 35th in Division 1, averaging 39.5 points per game. They average 403.0 yards of offense per game, placing them 63rd in the D-1 rankings. Louisville has incurred 155 yards in penalties across 17 infractions, ranking them 73rd nationally in penalty yards. They have thrown 3 interceptions and lost 1 fumble while gaining 40 first downs. This season, they have compiled 464 passing yards, averaging 232.0 yards per game, which ranks 66th in the nation. Additionally, the Cardinals boast an average of 171.0 rushing yards per game, totaling 342 rushing yards for the year.
On defense, Louisville has allowed a total of 200 rushing yards, averaging 100.0 yards per game, and has conceded 2 rushing touchdowns this season. They have given up 1 passing touchdown and are allowing 106.5 passing yards per game, ranking 7th in the nation. Overall, the Cardinals have allowed 31 points across all games played. They have recorded 1 fumble recovery and 1 interception this season. Their defense has been on the field for 131 plays, ranking 14th in the nation, while allowing an average of 15.5 points per game, placing them 37th nationally.
Who will prevail in this Falcons vs. Cardinals college football clash against the spread?
Expert Prediction: Bet on the Falcons +26.5
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