Central Michigan Chippewas vs Pittsburgh Panthers Forecast, 9/6/2025 College Football Selections, Top Bets & Odds

Home » Central Michigan Chippewas vs Pittsburgh Panthers Forecast, 9/6/2025 College Football Selections, Top Bets & Odds

Matchup: Central Michigan Chippewas vs Pittsburgh Panthers

Date: Saturday, September 6, 2025

Venue: Acrisure Stadium, Pittsburgh, PA

Broadcast: ESPN/ESPN+

Betting Odds: Panthers favored by 22.0 points

Total Points Over/Under: 52

The Central Michigan Chippewas (1-0) are set to clash with the Pittsburgh Panthers (1-0) at Acrisure Stadium on Saturday, September 6, 2025. Pittsburgh enters the matchup as 22.0-point favorites, with the total points over/under set at 52.

This season, the Central Michigan Chippewas have registered a record of 1-0. In their most recent outing, they triumphed over the San Jose State Spartans, winning 16-14. The Chippewas executed 64 plays, amassing a total of 351 yards. On the ground, they rushed 51 times, gaining 236 yards, averaging 4.6 yards per carry. Defensively, Central Michigan allowed 75 yards on 24 rushing attempts, yielding 3.1 yards per rush. Additionally, they permitted 24 completions out of 45 attempts, resulting in 308 passing yards and a completion rate of 53.3%.

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When it comes to scoring, the Central Michigan Chippewas average 16.0 points per game. In terms of rushing offense, they average 236.0 yards per game, placing them 27th in Division 1. The Chippewas have accumulated a total of 351 yards this season, scoring just one rushing touchdown. They have achieved 20 first downs and incurred 7 penalties for 33 yards while maintaining a clean turnover record.

Defensively, the Chippewas rank 63rd in Division 1, surrendering 14.0 points per game. They allow 3.1 yards per carry and 75.0 rushing yards per game this season, having conceded a total of 75 rushing yards through one game. In the passing game, Central Michigan allows 308 yards, ranking 121st nationally, with a completion percentage of 53.3%. Overall, they have given up an average of 383.0 yards per game, ranking 103rd in the nation, including 2 passing touchdowns.

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The Pittsburgh Panthers enter this contest with a record of 1-0. In their last game, they dominated the Duquesne Dukes, winning 61-9. The Panthers recorded a total of 460 yards on 65 plays, averaging 7.1 yards per play. They rushed for an impressive 5.9 yards per attempt, accumulating 158 yards on 27 carries. On defense, Pittsburgh allowed 31 rushing attempts for just 37 yards (1.2 yards per carry) and the secondary yielded a completion percentage of 63.0%, giving up 171 yards on 17 of 27 passes.

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In terms of scoring, the Panthers rank 7th nationwide, averaging 61.0 points per game. Their offensive output is substantial, with an average of 460.0 yards per game, ranking them 36th in the nation. They have incurred 35 yards in penalties from 3 infractions, placing them 114th in Division 1. So far, Pittsburgh has achieved 21 first downs and accumulated 302 passing yards, which ranks 22nd in the country, coupled with 158 rushing yards per game.

Pittsburgh’s defense is allowing just 9.0 points per game, making them 36th in Division 1. They have surrendered a mere 37 rushing yards total and only 1 passing touchdown, with 171.0 yards allowed through the air per game. Their defensive unit has completed 58 plays, ranking them 36th nationally, and they have yet to force a turnover.

Who do you think will emerge victorious in this Chippewas vs Panthers matchup against the spread?

Tony’s Prediction: Take the Panthers -22.0

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