Chicago Cubs vs Chicago White Sox Prediction for 7/27/2025 MLB Picks, Best Bets & Odds

Home » Chicago Cubs vs Chicago White Sox Prediction for 7/27/2025 MLB Picks, Best Bets & Odds

Matchup: Chicago Cubs vs Chicago White Sox

Date: Sunday, July 27, 2025

Venue: Rate Field, Chicago, IL

Broadcast: Chicago Sports Network

Odds/Point Spread: Chicago Cubs (-275) | Chicago White Sox (+220)

This exciting matchup at Rate Field pits the Chicago White Sox (37-66) against the Chicago Cubs (60-42) on Sunday. Current odds place the Cubs at -275, while the White Sox are at +220. The total score is projected at 9 runs, with Ben Brown and Sean Burke slated as the starting pitchers.

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The Chicago Cubs are currently averaging 5.3 runs per game, securing their place as the 2nd highest-scoring team in the league. They have accounted for a total of 537 runs with an on-base percentage of .324. The Cubs have collectively hit 173 doubles and 152 home runs, totaling 525 RBIs and 899 hits this season, while maintaining a batting average of .256. The team boasts a slugging percentage of .446 and has struck out 784 times, while drawing 346 walks.

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With a K/BB ratio of 2.81, the Cubs’ pitching squad showcases a combined WHIP of 1.22. The pitching staff has allowed 128 home runs and 420 runs, placing them 11th in the league. With 841 total hits conceded (8.3 per 9 innings) and a total of 390 earned runs, the Cubs’ ERA stands at 3.86 this season (13th in baseball). The staff has accumulated 764 strikeouts while issuing 272 walks, yielding a FIP of 4.25 for the campaign.

This season, the Cubs have utilized 335 relievers, with bullpen pitchers inheriting 96 runners; of those, 29.2% have scored. They’ve compiled 24 saves out of 35 opportunities, leading to a save percentage of 68.6%. Moreover, their relief pitchers have made 101 appearances in save situations, earning 63 holds this season (10th in MLB). Cubs relievers have encountered runners on base 70 times in high-leverage situations.

The Boston Red Sox have achieved 2,729 putouts this season, compiling 864 assists with 42 errors. Their fielding percentage is currently .988, ranking them 5th in professional baseball, with 83 double plays turned. The Cubs have converted 71.4% of balls put into play into outs over their 8,187 innings, placing them 3rd in the league.

Ben Brown (5-10 career record) holds a FIP of 5.26, having faced 600 batters in the major leagues. He has allowed 142 hits (9.2 hits per nine innings) and issued 46 walks, with an ERA of 5.34 (82 earned runs allowed) and a career WHIP of 1.360 across 138 innings pitched, recording 159 strikeouts so far.

The Chicago White Sox are struggling with a team slugging percentage of .354, averaging only 3.70 runs per game (27th in MLB). They have hit 166 doubles and drawn 340 walks, accumulating 381 runs this season. With 85 home runs, they have recorded 365 RBIs but have also struck out 881 times (10th in the league) and have 756 base hits to their name. Their on-base percentage stands at .298 and batting average at .224 this season.

As a team, the White Sox’s WHIP is 1.378, with a FIP of 4.45. Ranking 19th in MLB, they have allowed 857 hits, yielding 453 runs over the season with an ERA of 4.08 (406 earned runs). Their strikeout-to-walk ratio is currently 7.50, reporting 751 strikeouts against 378 walks. The team has conceded 109 home runs and allows 4.55 runs per 9 innings (21st in the league).

With 72 save opportunities, the White Sox relievers have garnered 43 holds but suffered 16 blown saves. In 29 save chances, they have secured just 13 saves. The bullpen has performed in 91 high-leverage situations and has entered games with runners on base 93 times. Chicago’s inherited score percentage for 136 inherited runners stands at 29.4%, placing them last in baseball with a save percentage of 44.8%, dispatching 324 relief pitchers this season.

Sean Burke (6-8 career record) holds an ERA of 3.75, allowing 8.1 hits per game. His strikeout-to-walk ratio is 1.98, having faced 520 batters in his career. So far, he has allowed 50 earned runs, recorded a WHIP of 1.350, and has a FIP of 3.7. Burke has permitted 108 hits and has compiled 107 strikeouts over 120 innings.

Who will emerge victorious in tonight’s MLB showdown, either against the spread or moneyline?

Guy Bruhn’s Prediction: Opt for Chicago (+220)

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