Chicago White Sox and Tampa Bay Rays Prediction for July 22, 2025: MLB Picks, Best Bets & Odds

Home » Chicago White Sox and Tampa Bay Rays Prediction for July 22, 2025: MLB Picks, Best Bets & Odds

Matchup: Chicago White Sox vs Tampa Bay Rays

Date: Tuesday, July 22, 2025

Venue: George M. Steinbrenner Field, Tampa, FL

Broadcast: FanDuel Sports Network Sun

Betting Odds: Chicago (+220) Tampa Bay (-275)

The Chicago White Sox (35-65) will visit George M. Steinbrenner Field on Tuesday, looking to secure a win against the Tampa Bay Rays (52-48). The odds for this matchup are set at +220 for Chicago and -275 for Tampa Bay, with a total score over/under of 8.5. The anticipated starting pitchers are Davis Martin for the White Sox and Drew Rasmussen for the Rays.

MLB Predictions: Taylor Walls, Tampa Bay Rays, Best Bets

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As a unit, the Chicago White Sox are averaging 3.6 runs per game, ranking 27th in the league. They have tallied a total of 359 runs this season while maintaining an on-base percentage of .298. The team has recorded 160 doubles and hit 80 home runs. Overall, Chicago has 344 runs batted in and 728 hits throughout the season, resulting in a batting average of .223. Their slugging percentage stands at .351, with 853 strikeouts and 331 walks.

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The White Sox boast a team earned run average of 4.07 this season, ranking 19th in the league, with their pitching staff striking out 720 batters. They have allowed 106 home runs and have given up a total of 437 runs (also 19th in the league). Their pitching unit has issued 361 walks, leading to a combined FIP of 4.45. Chicago has surrendered 832 hits (8.6 per 9 innings) and 394 earned runs, with a K/BB ratio of 1.99 and a WHIP of 1.37.

Throughout the season, the White Sox have deployed 311 relief pitchers. These relievers have inherited 125 base runners, with 28% crossing home plate. They have successfully recorded 12 saves while failing to convert 16 out of 28 save chances, resulting in a save rate of 42.9%. In total, they have entered 70 save situations and achieved 42 holds (27th in the league). White Sox relief pitchers have faced runners on base 87 times and have 88 appearances in critical game situations.

The Chicago Cubs have accumulated 2,531 putouts so far, along with 799 assists and 58 errors. Their fielding percentage is .983, ranking 25th in MLB, and they have turned 81 double plays. The White Sox have converted 69.9% of balls in play into outs over 7,593 innings, placing them at 17th in professional baseball.

Martin has pitched 193 innings in his career, amassing 148 strikeouts. With a career record of 5-18, Martin has a FIP of 4.22 and has faced 823 batters in the majors. His ERA stands at 4.28 (allowing 92 earned runs) and he has a WHIP of 1.314 with 193 hits allowed (9.0 hits per nine innings) and 61 walks.

Tampa Bay boasts 110 home runs this season, contributing to 440 runs batted in. They have also hit 154 doubles, drawn 297 walks, and scored 467 runs overall. The Tampa Bay Rays currently hold an on-base percentage of .320 and a batting average of .258. They have a slugging percentage of .406 and are averaging 4.67 runs per game (9th in MLB). They have recorded 820 strikeouts (16th in MLB) and achieved a total of 870 hits.

The Rays have a combined WHIP of 1.198 and a FIP of 4.21, ranking 10th in MLB for fewest hits allowed with 787. They have conceded 397 runs this season with a team ERA of 3.76 (371 earned runs). Their strikeout-to-walk ratio stands at 8.40, striking out 826 batters to 278 walks. They have allowed 130 home runs and give up 4.02 runs per 9 innings (7th in MLB).

In 93 save opportunities, the Rays have recorded 54 holds and experienced 16 blown saves. They have sent relief pitchers to the mound in 38 save situations, successfully converting 22 of these into saves. Their relievers have appeared 92 times in high-leverage situations and 71 times with runners on base. Tampa Bay’s relievers have a 36.9% inherited scoring percentage out of 103 inherited runners and rank 22nd in baseball with a save rate of 57.9%, having utilized 308 relief pitchers this season.

Through 7,764 innings this season, the Rays have achieved a defensive efficiency of 71.4% (5th in professional baseball). They have also turned 97 double plays and hold a fielding percentage of .987 (12th in the majors). The Rays have recorded 887 assists, 46 errors, and achieved a total of 2,588 putouts.

Rasmussen, with a career record of 27-17, owns a 2.94 ERA and has allowed 7.4 hits per nine innings. His strikeout-to-walk ratio is 3.63, having faced 1,610 batters in his career. He has given up 131 earned runs, holds a WHIP of 1.077, and has a FIP of 2.90. Throughout his time in MLB, Rasmussen has allowed 328 hits while recording 378 strikeouts in 401 innings.

Who will come out on top in tonight’s MLB showdown against the spread or moneyline?

Guy Bruhn’s Prediction: Favor Tampa Bay (-275)

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