Chicago White Sox Facing Cleveland Guardians Prediction, 9/13/2025 MLB Picks, Top Bets & Odds

Home » Chicago White Sox Facing Cleveland Guardians Prediction, 9/13/2025 MLB Picks, Top Bets & Odds

Matchup: Chicago White Sox vs Cleveland Guardians

Date: Saturday, September 13, 2025

Venue: Progressive Field, Cleveland, OH

Broadcast: CLEGuardians.TV

Betting Odds: Chicago (+126) Cleveland (-152)

The Chicago White Sox (56-90) visit Progressive Field this Saturday, aiming to secure a victory against the Cleveland Guardians (74-71). The opening odds list Chicago at +126 and Cleveland at -152, with an over/under set at 9 runs. Scheduled to pitch are Davis Martin and Parker Messick.

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The White Sox currently have a team slugging percentage of .379 and have struck out 1,218 times, with 457 walks logged. They’ve amassed 572 RBIs and 1,146 hits this season, maintaining a batting average of .236. As a unit, they hit 227 doubles and have launched 150 home runs, totaling 592 runs and boasting an on-base percentage of .305. Chicago scores an average of 4.1 runs per game, placing them 26th in the league.

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The White Sox sports a team ERA of 4.25, ranking 20th in the league, and their pitchers have recorded 1,141 strikeouts. The staff has allowed 166 home runs, contributing to a total of 672 runs allowed (21st in the league). They have issued 542 walks with a team FIP of 4.48. Opponents have racked up 1,204 hits against them (8.5 per 9 innings), leading to 603 earned runs. Their strikeout-to-walk ratio stands at 2.11, with an overall WHIP of 1.37.

White Sox relievers have entered games with players on base 147 times and have made 140 high-leverage appearances. The bullpen has achieved 63 holds this year, ranking 27th in the league, with a save percentage of 52.3%. In 109 save situations, they have successfully converted 23 saves, missing 21 of their 44 opportunities. They have inherited 214 base runners, with 32.2% eventually scoring. The White Sox have utilized 475 relief pitchers this season.

The White Sox have converted 69.7% of batted balls into outs over 11,505 innings, positioning them 16th in MLB. The team has achieved 3,835 putouts, 1,160 assists, and 95 errors this season, maintaining a fielding percentage of .981, which is 28th among professional teams, along with 117 double plays.

Davis Martin has pitched 240 innings, striking out 187 batters throughout his MLB journey. With a career win-loss record of 9-20, Martin’s FIP stands at 4.24, having faced 1,023 batters. His earned run average is 4.31 (115 earned runs), complemented by a career WHIP of 1.324. He has allowed 232 hits (8.7 hits per 9 innings) and issued 86 walks.

The Guardians have a team slugging percentage of .370, averaging 3.91 runs per game (27th in the league). They have registered 211 doubles, drawn 444 walks, and scored 567 runs. Cleveland has also hit 148 home runs and recorded 547 RBIs. The team has struck out 1,204 times (17th in the league) and achieved 1,072 hits. Their on-base percentage stands at .297, with a team batting average of .225 this season.

The Guardians’ pitching staff holds a team WHIP of 1.303 and a FIP of 4.10. They rank 14th in MLB for total hits allowed with 1,187. Cleveland’s pitchers have given up 606 runs this season, maintaining a team ERA of 3.87 (554 earned runs). Their strikeout-to-walk ratio is 8.40 (1,195 strikeouts against 491 walks), with 155 home runs allowed, yielding 4.23 runs per 9 innings (11th in baseball).

Cleveland has relied on their bullpen in 61 save opportunities, achieving 42 saves and ranking 5th in the league with a save percentage of 68.9%. They have sent 475 relievers to the mound this season. Their bullpen has participated in 167 high-leverage situations and 134 appearances with base runners. The Guardians’ relievers have inherited 187 runners, with a scoring rate of 33.7%. In 159 save chances, they’ve recorded 95 holds, alongside 19 blown saves.

Across 11,592 innings played, the Guardians have achieved a defensive efficiency rate of 69.5% (19th in the majors). Cleveland has executed 112 double plays, maintaining a .983 fielding percentage (27th in professional baseball). The team has made 1,198 assists, 89 errors, and accumulated 3,864 putouts this season.

Parker Messick has allowed 28 hits while achieving 18 strikeouts in 23 innings pitched throughout his MLB career. With a career win-loss record of 2-0, Messick holds a 1.95 ERA and has allowed 10.9 hits per nine innings. He has conceded 5 earned runs, yielding a WHIP of 1.342 and a FIP of 1.9. His strikeout-to-walk ratio is 6.00, having faced 96 batters in total.

Who do you think will clinch tonight’s MLB matchup against the spread or on the moneyline?

Tony Sink’s Prediction: Back Chicago (+126)

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