- Matchup: Clemson Tigers vs North Carolina Tar Heels
- Event Date: Saturday, October 4, 2025
- Venue: Kenan Stadium, Chapel Hill, NC
- Broadcast: ESPN
- Bets/Point Spread: Tar Heels (+14.0)
- Over/Under Total: 45.5
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The Clemson Tigers (1-3) will face off against the North Carolina Tar Heels (2-2) at Kenan Stadium on Saturday, October 4, 2025. Betting odds open with the Tigers favored by 14.0 points, while the over/under is set at 45.5.
Entering this matchup, the Clemson Tigers have struggled with a 1-3 record this season. In their most recent game, they faced off against the Syracuse Orange and suffered a defeat with a score of 34-21. During that game, Clemson executed 83 plays, accumulating 503 yards of total offense. The Tigers managed to rush the ball 22 times for 140 yards, averaging 6.4 yards per carry. Defensively, they allowed the Orange to rush for 155 yards on 38 attempts, giving up an average of 4.1 yards per carry. In the passing game, Clemson conceded 21 completions from 39 attempts, totaling 278 yards with a 53.8% completion rate.

So far this season, the Tigers have compiled a total of 1,461 yards. In terms of scoring, Clemson has thrown for 6 passing touchdowns and rushed for 4 touchdowns. Unfortunately, they have also turned the ball over 7 times. The team has generated 76 first downs while committing 19 penalties for a total of 187 yards. Their rushing offense averages 116.3 yards per game, placing them 112th in Division 1. Overall, the Clemson Tigers average 19.8 points per game.
On the defensive side, Clemson ranks 63rd nationally, allowing 22.8 points per game. Rivals are gaining an average of 3.4 yards per carry and 121.8 rushing yards per game against them. Through four games, they have surrendered a total of 487 rushing yards. In the air, the Tigers have allowed 961 passing yards, ranking them 69th in Division 1, which breaks down to an average of 240.3 yards allowed per game and a completion percentage of 65.0%. They have given up 5 touchdowns through the air and 4 on the ground, with a total of 362.0 yards allowed per game, ranking them 73rd nationwide.
The Tar Heels head into this contest with a 2-2 record. Their last outing resulted in a disappointing loss, with a final score of 34-9 against the UCF Knights. During that game, North Carolina managed 217 total yards over 58 plays, averaging just 3.7 yards per play. The Tar Heels rushed for 63 yards on 25 carries, averaging 2.5 yards per attempt. Meanwhile, they allowed 34 rush attempts for 143 yards (4.2 yards per carry). In the secondary, they had a hard time, allowing a completion rate of 78.1%, with 223 yards given up on 25 out of 32 passing attempts.
In terms of points scored, the Tar Heels rank 106th nationally with an average of 21.0 points per game. Their offense generates only 263.5 yards per game, ranking them 134th in Division 1 football. The North Carolina team has committed 180 yards worth of penalties over 17 infractions, which is 125th overall in college football. They’ve thrown 4 interceptions and lost 2 fumbles while managing to achieve 55 first downs. This season, they have accumulated 600 passing yards, averaging 150.0 yards through the air per game, placing them at 124th in the nation. On the ground, they average 113.5 rushing yards per game for a total of 454 yards this season.
Defensively, the Tar Heels have allowed 546 rushing yards (136.5 yards per game) and 5 rushing touchdowns this season. Through the air, they have given up 3 touchdowns and an average of 208.0 passing yards per game, ranking them 64th nationally. Over the course of the season, they have surrendered a total of 91 points. Their defensive efforts have resulted in 2 fumble recoveries and 4 interceptions. The North Carolina defense has taken to the field for 272 plays, positioning them 47th in the nation, while allowing 22.8 points per game, ranking them 61st overall.
Who will emerge victorious in this exciting Tigers vs Tar Heels college football matchup against the spread?
Prediction: Bet on the Tigers -14.0
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