Clemson Tigers vs South Carolina Gamecocks Prediction for 11/29/2025: College Football Picks, Best Bets & Odds

Home » Clemson Tigers vs South Carolina Gamecocks Prediction for 11/29/2025: College Football Picks, Best Bets & Odds

  • Matchup: Clemson Tigers vs South Carolina Gamecocks
  • Date: Saturday, November 29, 2025
  • Venue: Williams-Brice Stadium, Columbia, SC
  • Broadcast: SEC Network
  • Point Spread: Gamecocks favored by (-3.0)
  • Over/Under Total: 46

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On Saturday, November 29, 2025, the South Carolina Gamecocks (4-7) are set to clash with the Clemson Tigers (6-5) at Williams-Brice Stadium. Clemson enters the matchup as 3.0-point underdogs, with an over/under of 46 points.

The Clemson Tigers, sporting a record of 6-5 this season, recently triumphed over the Furman Paladins with a decisive 45-10 victory. In that game, the Tigers executed 31 rushing plays, amassing 219 rushing yards, averaging 7.1 yards per carry. Overall, they ran 67 plays totaling 456 yards. Defensively, Clemson allowed 25 completions out of 42 attempts for 205 passing yards, translating to a completion rate of 59.5%. Against the rushing attack, the Tigers yielded 66 yards on 28 attempts, averaging 2.4 yards per rush.

Clemson Tigers football predictions and odds

This season, the Tigers have accumulated a total of 4,448 yards. In terms of touchdown production, they have scored 22 through the air and 17 on the ground, while turning the ball over 14 times. Clemson leads the stat sheet with 233 first downs and has incurred 50 penalties totaling 497 yards. Their rushing average stands at 129.8 yards per game, placing them 98th nationally. Offensively, they average 28.7 points per game.

Defensively, the Tigers stand at 35th in the nation, allowing 21.0 points per game. Opponents are rushing for an average of 3.6 yards per attempt, totaling 108.5 rushing yards per game across the season. Clemson has given up 1,194 rushing yards in 11 games. In the passing department, they have allowed 2,625 yards, ranking them 93rd nationally. Opponents complete 60.8% of their passes against Clemson, yielding 238.6 yards per game. Altogether, they permit 347.1 yards per game, slotting them at 46th in college football, with 14 passing touchdowns and 10 rushing touchdowns surrendered.

The South Carolina Gamecocks, with a record of 4-7 this season, recently secured a dominant victory, defeating the Coastal Carolina Chanticleers 51-7. They recorded an impressive 6.8 yards per rush and finished the game with 264 rushing yards on 39 attempts. The Gamecocks accumulated a total of 579 yards and executed 69 offensive plays, averaging 8.4 yards per play. Their pass defense allowed a completion rate of 75.0%, yielding 174 yards from 27 completions on 36 attempts, while surrendering just 38 yards on 29 rush attempts (1.3 yards per carry).

The South Carolina offense averages 328.5 yards per game, ranking 112th in Division 1. They have accumulated 633 yards in penalties from 83 infractions, which positions them 16th in Division 1 for penalty yards. Rushing-wise, South Carolina averages 117.5 yards per game, totaling 1,293 yards this season. They have thrown 9 interceptions and lost 6 fumbles, achieving 194 first downs. On the scoring front, the Gamecocks rank 99th in college football with an average of 23.5 points per game. Thus far, they have recorded 2,322 passing yards, averaging 211.1 yards per game, placing them 86th in Division 1.

Defensively, South Carolina has allowed 1,485 rushing yards (135.0 yards per game) and 11 rushing touchdowns this year. They have yielded 13 passing touchdowns, giving up 211.6 yards per game, ranking 57th in Division 1. In total, the Gamecocks have surrendered 237 points this season. Their defense has recovered 10 fumbles and intercepted 11 passes. With 727 plays run against them, their defense ranks 60th in Division 1. South Carolina concedes 21.5 points per game, placing them 40th nationally.

Who will come out on top in this exciting matchup between the Tigers and the Gamecocks?

Prediction: Bet on the Gamecocks -3.0

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Pick: South Carolina Gamecocks -3
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