Matchup: Cleveland Guardians vs Detroit Tigers
Date: Tuesday, September 16, 2025
Venue: Comerica Park, Detroit, MI
Broadcast: FanDuel Sports Network Detroit
Betting Odds: Cleveland (+132) Detroit (-160)
On Tuesday, the Detroit Tigers (85-65) will host the Cleveland Guardians (78-71) at Comerica Park. The Guardians are set at a moneyline of +132, while the Tigers open at -160. The total over/under for the game is positioned at 8.5. Expected to take the mound are pitchers Joey Cantillo for Cleveland and Casey Mize for Detroit.


The Cleveland Guardians average 3.9 runs per game, ranking them 27th in the MLB. Currently, they have amassed 580 runs with a team on-base percentage of .296. The Guardians have hit 216 doubles and reached the outfield 154 times this season. They have recorded 560 RBIs and 1,095 hits, leading to a team batting average of .225. Cleveland also boasts a slugging percentage of .370, with 1,224 strikeouts and 452 walks drawn.
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The Guardians possess a team ERA of 3.80, ranking 6th in the league, with a total of 1,236 strikeouts this season. Cleveland’s pitchers have allowed 157 home runs and 611 total runs (ranking 8th in MLB). They have issued 497 walks, and their team FIP stands at 4.06. So far, they have given up 1,207 base hits (averaging 8.2 per 9 innings) and allowed 559 earned runs. Their K/BB ratio is 2.49, with a WHIP of 1.29.
The Guardians’ bullpen has a save percentage of 70.3%, appearing in 165 save situations. They have inherited 188 runners this year, with 33.5% scoring. Guardians pitchers have entered games with runners on base 135 times and have faced 174 high-pressure situations. Cleveland’s relievers have made 486 appearances this season, achieving 98 holds (5th in MLB) and converting 45 of 64 save opportunities.
This season, the Cincinnati Reds total 3,972 putouts, 1,231 assists, and 90 errors, giving them a fielding percentage of .983, ranking 27th in MLB. The Guardians have converted 69.7% of balls hit into play into outs over their 11,916 innings, marking them 19th in the league.
Starting pitcher Joey Cantillo holds a career record of 7-7, with a FIP of 3.82 across 504 faced batters. He has given up 102 hits (averaging 7.8 per 9 innings) and issued 53 walks. With an ERA of 3.88 (51 earned runs) and a WHIP of 1.310, Cantillo has pitched 118 innings and struck out 136 batters in his professional career.
The Tigers possess a slugging percentage of .420, averaging 4.86 runs per game (8th in the league). They have recorded 232 doubles, walked 473 times, and accumulated 729 runs. The team has hit 187 home runs with 695 RBIs, while striking out 1,323 times (6th in the league) and accumulating 1,259 base hits. Detroit’s OBP stands at .318, with a batting average of .249 this year.
With a WHIP of 1.238, Detroit’s pitching staff has a FIP of 4.07. Their K/BB ratio is an impressive 8.50 (1,264 strikeouts against 442 walks). They rank 12th in hits allowed with a total of 1,206, having given up 174 homers and 4.29 runs per nine innings (12th in MLB). The Tigers have surrendered 634 runs this season, along with a team ERA of 3.91 (578 earned runs).
The Tigers’ relievers have inherited 231 runners, with an inherited score percentage of 28.6%. They have been called upon in 129 high-leverage situations and 163 times with runners on base. In 132 save opportunities, Detroit has recorded 70 holds and 20 blown saves. They rank 9th in MLB with a save rate of 65.5%, dispatching 461 bullpen pitchers throughout the year. They have been involved in 58 save situations, securing 38 saves.
In a total of 11,979 innings, the Tigers have achieved a defensive efficiency of 70.3% (12th in MLB). With 123 double plays and a fielding rate of .986 (16th in professional baseball), the Tigers have tallied 1,290 assists, 75 errors, and 3,993 putouts this season.
Throughout his career, pitcher Casey Mize has conceded 428 hits while accumulating 344 strikeouts over 422 innings. He has allowed 197 earned runs, maintains a WHIP of 1.291, and a FIP of 4.1. Mize’s K/BB ratio is 2.94, facing 1,796 opposing hitters during his career. With a career record of 23-24, he holds an ERA of 4.20 while allowing 9.1 hits per nine innings.
Who will triumph in tonight’s matchup, covering the spread or claiming the moneyline?
Tony Sink’s Recommendation: Bet on Cleveland (+132)
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