Detroit Lions vs Kansas City Chiefs Forecast, 10/12/2025 NFL Selections, Top Bets & Odds Week 6

Home » Detroit Lions vs Kansas City Chiefs Forecast, 10/12/2025 NFL Selections, Top Bets & Odds Week 6

  • Matchup: Detroit Lions vs Kansas City Chiefs
  • Date: Sunday, October 12, 2025
  • Venue: GEHA Field at Arrowhead Stadium, Kansas City, MO
  • Broadcast: NBC
  • Point Spread: Chiefs (+1)
  • Total Points Over/Under: 50.5

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This Sunday’s clash pits the Kansas City Chiefs (2-3) against the Detroit Lions (4-1) at the iconic GEHA Field at Arrowhead Stadium. Kansas City enters as 1-point underdogs, and the predicted point total is set at 50.5.

The Detroit Lions boast a strong 4-1 record this season. Their most recent victory came against the Cincinnati Bengals, where they secured a 37-24 win. Jared Goff excelled, completing 19 of 23 passes for 258 yards and 3 touchdowns, achieving a stellar quarterback rating of 153 without any interceptions. David Montgomery led the ground game with 18 carries for 65 yards, averaging 3.6 yards per attempt. Amon-Ra St. Brown made impactful receptions, totaling 100 yards on 8 catches, averaging 12.5 yards per reception. The Lions accumulated 118 rushing yards on 33 attempts, averaging 3.6 yards per carry. Overall, they executed 57 plays for 365 total yards. On the defensive side, Detroit allowed the Bengals to complete 26 passes on 40 attempts, totaling 237 yards with a 65% completion rate. Against the run, they surrendered 85 yards on 16 carries, averaging 5.3 yards per run.

NFL predictions and betting odds for Patrick Mahomes and the Kansas City Chiefs

This season, the Lions have amassed 1,825 total yards, achieving 62 first downs, although they’ve suffered from 32 penalties totaling 227 yards. They’ve displayed their offensive prowess with 13 passing touchdowns and 8 rushing touchdowns, while giving up the ball only 3 times (2 interceptions and 1 fumble). With an impressive average of 134.8 rushing yards per game, they rank 7th in the league, while scoring an average of 34.8 points per game.

Defensively, the Lions rank 17th in terms of opponent scoring, yielding 22.4 points per game. They allow 4.0 yards per carry and 92.2 rushing yards per game. In total passing defense, they’ve conceded 1,033 yards, putting them 13th in the NFL, with an average of 206.6 passing yards allowed and a completion percentage of 63.3%. Overall, they allow an average of 298.8 yards per game, ranking 8th in the league, with 10 passing touchdowns and 4 rushing touchdowns allowed. On the season, they’ve given up a total of 461 rushing yards over 5 games.

The Kansas City Chiefs enter this matchup with a 2-3 record. Their last encounter resulted in a narrow 31-28 defeat to the Jacksonville Jaguars. Kareem Hunt carried the ball 7 times, gaining 49 yards with an impressive average of 7.0 yards per carry. Travis Kelce was a key target, securing 7 passes for 61 yards (8.7 yards per reception). Patrick Mahomes threw for 318 yards with 1 touchdown on 29 of 41 completions, ending with a quarterback rating of 91.3. He also threw 1 interception and averaged 7.8 yards per pass attempt. Defensively, Kansas City permitted 26 rush attempts for 109 yards (4.2 yards per carry), while their passing defense allowed 210 yards from 18 completions out of 25 attempts, making for a completion rate of 72%. The Chiefs totaled 476 yards during the game, completing 63 plays for an average of 7.6 yards per play, with a rushing average of 7.2 yards on 22 carries for a total of 158 yards.

The Chiefs average 361.0 yards per game, placing them 8th in the NFL. They achieve an average of 120.0 rushing yards per game, totaling 600 yards so far. With 2 interceptions and no fumbles lost, they’ve recorded 59 first downs this season. The Chiefs have committed 42 penalties, which has led to 350 yards for their opponents, ranking them 7th in the league in this category. They’ve accumulated a total of 1,205 passing yards, averaging 241.0 yards per game, ranking 9th in scoring with an average of 25.0 points per game.

Defensively, the Chiefs are yielding 21.4 points per game, ranking 13th in the NFL. They’ve allowed 5 passing touchdowns and average 190.6 passing yards against, placing them 7th in the league. In terms of run defense, they’ve surrendered 617 rushing yards (123.4 yards per game) and 6 rushing touchdowns this season. The defensive unit has participated in 288 plays this season, placing them 9th overall. They’ve created 6 turnovers (2 forced fumbles and 4 interceptions), allowing a total of 107 points thus far.

Which team will come out on top in this Lions-Chiefs NFL matchup?

Prediction: Choose the Lions -1

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Pick: Detroit Lions -1
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