Detroit Tigers vs Cleveland Guardians Forecast, 9/23/2025 MLB Selections, Top Wagers & Odds

Home » Detroit Tigers vs Cleveland Guardians Forecast, 9/23/2025 MLB Selections, Top Wagers & Odds
  • Matchup: Detroit Tigers vs. Cleveland Guardians
  • Date: Tuesday, September 23, 2025
  • Venue: Progressive Field, Cleveland, OH
  • Broadcast: CLEGuardians.TV
  • Betting Odds: Detroit (-128) | Cleveland (+106)

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The Detroit Tigers (85-71) are headed to Progressive Field this Tuesday to face off against the Cleveland Guardians (84-72). Betting lines place Detroit at -128 and Cleveland at +106, with a total set at 8 runs. The starting pitchers are Tarik Skubal and Gavin Williams.

MLB Predictions: Jose Ramirez Cleveland Guardians Odds

The Tigers boast a slugging percentage of .417 and have been struck out 1,374 times this season, while walking 486 times. With 707 RBIs and 1,291 hits, their batting average stands at .247. The team has also recorded 236 doubles and hit 193 home runs. Collectively, the Tigers score an average of 4.8 runs per game, placing them 9th in the league.

Detroit’s pitching staff has produced an earned run average of 3.97 (15th in MLB), striking out 1,311 batters. They have allowed 183 home runs and given up a total of 664 runs (14th in the league). The team’s FIP (Fielding Independent Pitching) is 4.11, with a WHIP of 1.25 and a strikeout-to-walk ratio of 2.83. The Tigers have allowed 1,254 hits this season (8.2 per 9 innings) and 607 earned runs.

The bullpen has a save percentage of 64.4% from 134 save situations. They have inherited 241 base runners this season, with 27.8% scoring. Tigers’ relief pitchers have faced runners on base 171 times in high-leverage scenarios, using 482 pitchers overall. Currently, they have 71 holds situated at 24th in baseball, completing 38 saves but missing 21 of 59 save chances.

Defensively, the Tigers have converted 70.3% of balls in play into outs through 12,393 innings, ranking 12th in MLB. They have made 4,131 putouts, 1,332 assists, and 75 errors, achieving a fielding percentage of .986, which positions them 13th in the league.

Starting pitcher Tarik Skubal (54-36 career record) holds a FIP of 3.04 and has faced 3,032 batters. Allowing 610 hits (7.2 per nine innings) and 169 walks, his ERA is 3.09 with a career WHIP of 1.025. Skubal has pitched 760 innings and logged 881 strikeouts throughout his career.

The Cleveland Guardians have an on-base percentage of .297 and a batting average of .227 this season. They rank 17th in the MLB with 1,283 strikeouts and have made 1,153 hits, alongside 162 home runs and 593 RBIs. Their slugging percentage is .374, averaging 3.96 runs per game, placing them at 27th in MLB. The team has also recorded 231 doubles and drawn 475 walks for a total of 614 runs scored.

Cleveland’s pitching staff has given up 619 runs, maintaining a team ERA of 3.69 with 565 earned runs. They have released 160 home runs and permit 4.04 runs per 9 innings, positioning 5th in the league. The Guardians have a WHIP of 1.269, a FIP of 3.99, and a strikeout-to-walk ratio of 8.50 (1,303 Ks vs. 513 walks). They rank 11th in total hits allowed, with 1,237 hits this season.

With 178 save situations, the Guardians have recorded 108 holds and suffered 21 blown saves. Cleveland’s relievers have entered 67 save opportunities, successfully converting 46 saves. They have pitched in 184 high-pressure scenarios and 142 times with runners on base, inheriting around 33.0% of 194 base runners. They are ranked 6th in MLB regarding save percentage at 68.7%, with 505 bullpen appearances this year.

In their 12,411 innings played, the Guardians have a fielding efficiency of 69.8% (18th in MLB). They have turned 120 double plays and recorded a fielding percentage of .983 (27th in professional baseball) with 1,287 assists, 95 errors, and 4,137 putouts this season.

Pitcher Gavin Williams has allowed 264 hits and recorded 321 strikeouts over 319 innings pitched. With a 17-20 career record, he posts a 3.55 ERA, allowing 7.4 hits per 9 innings and giving up 126 earned runs. He has a FIP of 3.5, a WHIP of 1.297, and a K/BB ratio of 2.14, having faced 1,357 batters during his career.

Who do you predict will come out on top in tonight’s MLB matchup against the spread or moneyline?

Prediction: Choose Cleveland (+106)

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Pick: Cleveland Guardians (+106)
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