Duke Blue Devils vs Clemson Tigers Forecast, 11/1/2025 College Football Selections, Top Bets & Odds

Home » Duke Blue Devils vs Clemson Tigers Forecast, 11/1/2025 College Football Selections, Top Bets & Odds

  • Matchup: Duke Blue Devils vs Clemson Tigers
  • Date: Saturday, November 1, 2025
  • Venue: Memorial Stadium, Clemson, SC
  • Broadcast: ACC Network
  • Betting Odds: Tigers favored by 3.5 points
  • Point Total: 56

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The Duke Blue Devils (4-3) are set to clash against the Clemson Tigers (3-4) at Memorial Stadium on Saturday, November 1, 2025. The Tigers enter the game as 3.5-point favorites, with the total set at 56 points.

This season, the Duke Blue Devils have recorded a 4-3 record. Their most recent outing ended in a defeat against the Georgia Tech Yellow Jackets, where they fell 27-18. In that game, the Blue Devils executed 76 plays, amassing 441 yards. They rushed the ball 32 times, gaining just 68 yards, averaging 2.1 yards per carry. On defense, Duke conceded 171 rushing yards on 36 attempts, yielding an average of 4.8 yards per run. In the aerial game, Duke allowed 14 completions out of 21 attempts, totaling 205 yards, with a completion percentage of 66.7%.

Clemson Tigers Predictions - College Football Picks

In terms of scoring, the Duke Blue Devils average 33.9 points per game, while gaining an average of 144.3 rushing yards, ranking 80th in NCAA Division 1. Throughout the season, they have recorded a total of 3,243 yards. Duke has accumulated 17 touchdowns passing and 12 on the ground. Additionally, they have achieved 166 first downs, but have incurred 50 penalties, costing them 499 yards, and they’ve turned the ball over 8 times.

Defensively, Duke ranks 82nd nationally, allowing 25.7 points per game. They give up an average of 3.6 yards per carry, with 130.0 rushing yards conceded per game, tallying a total of 910 rushing yards over 7 games. In passing defense, the Blue Devils have surrendered 1,721 yards, ranking 78th in Division 1, allowing an average of 245.9 yards through the air and a completion rate of 67.6%. Overall, this season, they have allowed a total of 375.9 yards per game, placing them 77th in the country. They’ve given up 6 passing touchdowns and 16 rushing touchdowns.

The Clemson Tigers enter this game with a 3-4 record. In their last match, they faced the SMU Mustangs, suffering a 35-24 loss. Clemson struggled on the ground with only 30 attempts for 35 yards, averaging 1.2 yards per carry. In total, they managed 352 yards on 72 plays, averaging 4.9 yards per play. Defensively, Clemson’s pass coverage allowed a completion rate of 53.5%, yielding 290 yards on 23 of 43 attempts, and they let the opponents run for 139 yards on 28 attempts, averaging 5.0 yards per rush.

Analyzing their scoring capabilities, Clemson ranks 79th in Division 1, averaging 26.0 points per game. With an average of 400.7 total yards per game, they sit at 60th in Division 1. This year, the Tigers have accumulated 309 penalty yards through 31 infractions, ranking 130th in the nation. They’ve thrown 6 interceptions, allowed opponents to recover 6 fumbles, and amassed 147 first downs. So far this season, Clemson has achieved a total of 1,990 passing yards, averaging 284.3 passing yards per game, which ranks them 22nd in the NCAA. On the ground, they average 116.4 rushing yards per game, totaling 815 rushing yards.

On defense, Clemson has given up 768 rushing yards this season (109.7 per game), allowing 8 rushing touchdowns. In the passing game, they’ve conceded 7 touchdowns along with an average of 227.9 yards per game, ranking 78th nationally. Overall, they have allowed 146 points, recorded 3 fumble recoveries, and made 5 interceptions this season. Clemson’s defense has been active for 472 plays, ranking 34th in Division 1, while allowing 20.9 points per game, placing them at 38th in college football.

Who will emerge victorious in this matchup between the Blue Devils and Tigers?

Expert Prediction: Pick the Tigers -3.5

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Pick: Clemson Tigers Forecast -3.5
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