Houston Astros vs Los Angeles Angels Forecast, 9/27/2025 MLB Selections, Top Bets & Odds

Home » Houston Astros vs Los Angeles Angels Forecast, 9/27/2025 MLB Selections, Top Bets & Odds
  • Matchup: Houston Astros vs Los Angeles Angels
  • Date: Saturday, September 27, 2025
  • Venue: Angel Stadium, Anaheim, CA
  • Broadcast: FanDuel Sports Network West
  • Betting Odds: Houston (-145) | Los Angeles (+125)

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The Los Angeles Angels (71-87) are set to square off against the Houston Astros (84-74) at Angel Stadium this Saturday. Current betting lines place the Astros at -145 and the Angels at +125, with an over/under total of 9 runs. The starting pitchers for this game are AJ Blubaugh and Caden Dana.

MLB Predictions and Best Bets for Houston Astros

As a collective unit, the Houston Astros are averaging 4.2 runs per game, which ranks them 25th in the league. They have accumulated 660 runs, accompanied by a .315 on-base percentage (OBP). The squad has produced 239 doubles and has launched 172 home runs. With a total of 630 runs batted in and 1,336 hits this season, their batting average is currently at .250. The Astros also maintain a slugging percentage of .396, and they have struck out 1,263 times while achieving 458 walks.

The Astros hold a team ERA of 3.88 this season (12th in MLB), having struck out 1,468 batters. The pitching staff has conceded 194 home runs and allowed 653 total runs (9th in MLB). They have walked 495 hitters, while their Fielding Independent Pitching (FIP) stands at 4.02. Houston has given up 1,228 hits, averaging 7.9 hits per 9 innings, and they have allowed 607 earned runs. The team’s strikeout-to-walk ratio is 2.97, and they have a WHIP of 1.22.

As a unit, the Astros’ relievers have achieved a save rate of 73.8% and have entered 152 save scenarios. They have inherited 177 runners, with 23.2% of those scoring. The Astros’ pitchers have faced opponents on base 127 times and have logged 166 high-leverage appearances. This season, they’ve utilized 506 relievers. The bullpen has achieved 88 holds (15th in MLB) and converted 45 saves, alongside 16 blown saves out of 61 save opportunities.

Defensively, the Astros have successfully converted 70.7% of balls in play into outs over 12,663 innings, ranking 9th in Major League Baseball. The Detroit Tigers have recorded 4,221 putouts, 1,248 assists, and 68 errors, displaying a fielding percentage of .988, placing them 8th in the league, with 102 double plays.

AJ Blubaugh has pitched 28 innings with 33 strikeouts in his career, holding an impressive earned run average of 1.93 (6 earned runs allowed) and a career WHIP of 0.821. He has surrendered 16 hits (5.1 hits per nine innings) and issued 7 walks, boasting a FIP of 1.90 with 108 batters faced in the majors.

The Los Angeles Angels have recorded 220 home runs and 638 runs batted in this season, contributing to 209 doubles and drawing 474 walks, leading to 662 runs scored. Their on-base percentage is .299 while their batting average sits at .226. The Angels have a slugging percentage of .398, averaging 4.19 runs per game (24th in MLB). They have struck out 1,590 times (1st in MLB) and gathered 1,185 hits.

Los Angeles holds a team WHIP of 1.436 and a FIP of 4.76. They possess a strikeout-to-walk ratio of 8.00 (1,243 strikeouts to 610 walks) and rank 26th in total hits allowed, yielding 1,394. The pitching staff has surrendered 213 home runs and gives up 5.24 runs per 9 innings (28th in MLB), with an overall ERA of 4.86 (754 earned runs conceded).

This season, Angels relievers have participated in 71 save opportunities, converting 37 saves. Ranking last in MLB with a save percentage of 52.1%, the Angels have used 543 relievers this year. Their bullpen has entered high-leverage situations 204 times and has faced runners on base 140 times, allowing 37.7% of inherited runners to score. Out of 156 save scenarios, they have achieved 82 holds while suffering 34 blown saves.

Throughout 12,558 innings, the Angels have a defensive efficiency of 68.8% (24th in baseball), totaling 158 double plays and a fielding percentage of .983 (26th in the majors) with 1,382 assists, 94 errors, and 4,186 putouts this season.

In his professional career, Caden Dana has allowed 39 hits while tallying 36 strikeouts in 35 innings pitched. With a career record of 1-5, he holds a lofty ERA of 7.41 and gives up 10.0 hits per 9 innings, having surrendered 29 earned runs with a WHIP of 1.790 and a FIP of 7.3, with a K/BB ratio of 1.50 against 167 opposing hitters throughout his MLB tenure.

Which team will prevail in tonight’s MLB matchup against the spread or moneyline?

Prediction: Bet on Houston (-145)

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Pick: Houston Astros (-145)
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