- Game: Iowa Hawkeyes vs USC Trojans
- Date: Saturday, November 15, 2025
- Location: Los Angeles Memorial Coliseum, Los Angeles, CA
- TV: BTN
- Odds/Point Spread: Trojans (-6.0)
- Total/Over-Under: 49.5
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This thrilling matchup at the Los Angeles Memorial Coliseum features the USC Trojans (7-2) squaring off against the Iowa Hawkeyes (6-2) on Saturday, November 15, 2025. USC is entering this contest as 6.0-point favorites, with the total set at 49.5 points.
The Iowa Hawkeyes bring a record of 6-2 into this game. Their most recent outing saw them fall to the Oregon Ducks, finishing with a score of 18-16. During that game, Iowa executed 61 plays for a total of 239 yards. The Hawkeyes managed to rush the ball 43 times, accumulating 101 yards, which translates to an average of 2.3 yards per carry. Defensively, they allowed 261 yards on 36 rushing attempts, equating to 7.3 yards per rush. In the passing game, Iowa conceded 13 completions on 21 attempts for 112 yards, yielding a completion rate of 61.9%.

This season, the Hawkeyes have accumulated a total of 2,543 yards. They have scored 5 touchdowns through the air and 20 on the ground, while turning the ball over 6 times. As a team, Iowa has recorded 139 first downs and has been penalized 19 times for 183 yards. In the rushing department, they are averaging 185.3 yards per game, ranking them 37th in college football. Their scoring average is 31.3 points per game.
When it comes to pass defense, Iowa has allowed 1,208 yards, putting them 4th in the nation. They give up an average of 151.0 yards per game through the air with a 55.8% completion percentage. Overall, Iowa’s defense ranks 3rd nationally, yielding 234.9 yards per game. They’ve allowed 4 touchdowns in the air and 7 on the ground, averaging 2.6 yards per rush against and 83.9 rushing yards per game. For the season, they have surrendered a total of 671 rushing yards across 8 games and rank 4th in college football, allowing just 13.1 points per game.
The Trojans come into this clash with a record of 7-2. In their last game, they triumphed over the Northwestern Wildcats, finishing 38-17. USC’s defense allowed 130 rushing yards on 25 attempts, averaging 5.2 yards per carry. Their passing defense faced a completion percentage of 66.7%, yielding 150 yards on 20 completions out of 30 attempts. Overall, the Trojans amassed 482 yards over 64 plays, averaging 7.5 yards per play and rushed for 5.8 yards per carry, totaling 173 yards on 30 carries.
Regarding scoring, the Trojans rank 9th in Division 1 with an average of 39.6 points per game. They are generating an impressive average of 503.2 yards per contest, good for 4th in the nation. USC has accrued 507 yards in penalties over 57 infractions, ranking 52nd in the country. They’ve thrown 6 interceptions and allowed 6 fumbles, while achieving 224 first downs. The Trojans’ passing game has totaled 2,727 yards this season, averaging 303.0 yards per game, also putting them at 9th in Division 1. Their rushing attack averages 200.2 yards per game, accumulating a total of 1,802 yards this year.
Defensively, USC allows 21.8 points per game, placing them at 42nd in Division 1. They have given up 1,275 rushing yards, averaging 141.7 yards per game and 8 rushing touchdowns so far this year. In pass defense, they have allowed 16 touchdowns and 205.1 yards per game, which ranks them 50th nationally. Their defense has participated in 563 plays, which ranks them 63rd in the country and includes 6 fumble recoveries and 9 interceptions for the year, surrendering a total of 196 points.
Who will emerge victorious in the Hawkeyes vs. Trojans college football game against the spread?
Pick: Back the Hawkeyes +6.0
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