Matchup: Iowa State Cyclones vs Arkansas State Red Wolves
Date: Saturday, September 13, 2025
Venue: Centennial Bank Stadium, Jonesboro, AR
Broadcast: ESPN/ESPN+
Betting Odds: Red Wolves (+20.5)
Total Points Over-Under: 55.5
The Arkansas State Red Wolves (1-1) are set to clash with the Iowa State Cyclones (3-0) on Saturday, September 13, 2025, at Centennial Bank Stadium. Iowa State enters the game as 20.5-point favorites, with the total set at 55.5.
Currently boasting a record of 3-0, the Iowa State Cyclones come off a victory against the Iowa Hawkeyes, finishing the game 16-13. In that match, the Cyclones rushed 30 times for a total of 104 yards, averaging 3.5 yards per carry. On offense, they executed 57 plays for 238 total yards. Defensively, Iowa State allowed 13 completions out of 24 attempts, yielding 83 passing yards for a completion rate of 54.2%. On the ground, the Cyclones permitted 131 yards on 39 attempts, averaging 3.4 yards per carry.

For the season, Iowa State has accumulated a total of 1,080 yards. They’ve scored a total of 6 touchdowns through the air and 5 on the ground while turning the ball over 3 times. The Cyclones have achieved 61 first downs this season and have incurred 9 penalties leading to 77 yards. Rushing-wise, they average 152.3 yards per game, ranking them 82nd in Division 1. Overall, they are scoring an average of 31.7 points per game.
Defensively, Iowa State has given up 482 passing yards, placing them at 98th nationally. They allow an average of 160.7 yards per game through the air while maintaining a completion percentage against of 58.8%. Overall, they give up 268.7 total yards per game, landing them at 39th in Division 1. To date, they’ve allowed 3 passing touchdowns and 2 rushing touchdowns, yielding an average of 3.7 yards per carry and 108.0 rushing yards per game. In three games, the Cyclones have conceded a total of 324 rushing yards and are ranked 44th nationally in points allowed, at 13.7 per game.
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The Arkansas State Red Wolves head into this matchup with a 1-1 record. Their recent outing ended in a 56-14 defeat against the Arkansas Razorbacks. During that game, the Red Wolves gained 285 total yards on 78 plays, averaging 3.7 yards per play. They finished with 153 rushing yards on 42 attempts, averaging 3.6 yards per carry. Defensively, Arkansas State allowed 321 rushing yards on 29 carries, yielding an alarming average of 11.1 yards per carry, while their pass defense allowed 309 yards on 20 completions out of 29 attempts, giving up a completion percentage of 69.0%.
In terms of scoring, the Red Wolves rank 70th in college football with an average of 28.0 points per game. They are posting an average of 388.5 yards per game, placing them 74th nationally. The offense has incurred 126 penalty yards on 13 fouls, ranking 51st in terms of helping their opponents. They have secured 48 first downs thus far this season. Arkansas State has thrown for 477 yards through the air, averaging 238.5 yards per game, which ranks them 61st in Division 1. They also average 150.0 rushing yards per game with a total of 300 rushing yards this season.
The Red Wolves’ defense has allowed 413 rushing yards over two games (206.5 yards per game) and 5 rushing touchdowns thus far. They have given up 6 touchdown passes along with an average of 290.5 passing yards per game, ranking them 125th in Division 1. This season, they’ve recorded 1 fumble and 2 interceptions. The Red Wolves’ defense has been on the field for 127 plays, ranking them 63rd in Division 1. They are allowing an average of 40.0 points per game, placing them at 129th in the nation.
Who will secure the victory in tonight’s game between the Cyclones and Red Wolves against the spread?
Josh’s Recommendation: Bet on the Cyclones -20.5
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