Kansas City Chiefs vs New York Giants Forecast, 9/21/2025 NFL Selections, Top Wagers & Odds Week 3

Home » Kansas City Chiefs vs New York Giants Forecast, 9/21/2025 NFL Selections, Top Wagers & Odds Week 3

This page may include affiliate links at no extra cost to you, thanks for your support.

  • Matchup: Kansas City Chiefs vs New York Giants
  • Scheduled Date: Sunday, September 21, 2025
  • Venue: MetLife Stadium, East Rutherford, NJ
  • Broadcasting Network: NBC
  • Betting Odds: Giants (+5.5)
  • Game Total: 45.5

The Kansas City Chiefs (0-2) will travel to MetLife Stadium this Sunday to take on the New York Giants (0-2). Oddsmakers have set the Chiefs as 5.5-point favorites, while the total is listed at 45.5.

To date, the Kansas City Chiefs have begun their season with a 0-2 record. In their most recent match against the Philadelphia Eagles, the Chiefs suffered a narrow defeat, losing 20-17. Quarterback Patrick Mahomes went 16 of 29 for 187 yards with one touchdown and one interception, earning a QB rating of 72.1. He showcased his rushing ability as well, leading the team with 66 yards on 7 carries (9.4 yards per attempt). Travis Kelce recorded 4 receptions for a total of 61 yards, averaging 15.3 yards per catch. The Chiefs rushed 26 times, gaining 121 yards for an average of 4.7 yards per carry, ultimately finishing the game with 294 total yards on 55 plays. Defensively, Kansas City allowed 15 completions on 22 attempts, totaling 94 yards with a completion rate of 68.2%. Against the run, they conceded 122 yards on 34 carries, averaging 3.6 yards per run.

NFL Picks: Theo Johnson's Predictions and Odds for the New York Giants

When it comes to scoring, the Kansas City Chiefs are averaging 19.0 points per game. Offensively, they are recording approximately 109.5 rushing yards per game, which ranks them 17th in the NFL. Overall, the Chiefs have accumulated 641 offensive yards this season, along with 16 first downs. However, they have also been penalized 16 times for a total of 116 yards, and they’ve turned the ball over once. In terms of touchdowns, Kansas City has scored 2 through the air and 2 on the ground.

Defensively, the Chiefs rank 20th in the league, allowing an average of 23.5 points per game. They permit 3.6 yards per rushing attempt and 106.0 rushing yards per game. In the passing game, they have allowed 398 yards, positioning them 15th in the league. Kansas City is surrendering an average of 199.0 passing yards per game with a completion percentage of 71.4%. Overall, they are conceding 305.0 yards per game, ranking them 13th in the NFL, having allowed 3 passing touchdowns and 2 rushing touchdowns over the course of the season.

The New York Giants are also 0-2 this season. In their last outing, they faced a significant challenge against the Dallas Cowboys, losing a high-scoring battle 40-37. Running back Cam Skattebo carried the ball 11 times for 45 yards, averaging 4.1 yards per carry. Wide receiver Malik Nabers was a standout, catching 9 passes for 167 yards (18.6 yards per reception). Quarterback Russell Wilson threw for 450 yards on 30 of 41 passing with 3 touchdowns, achieving a remarkable QB rating of 123, despite tossing one interception and averaging 11.0 yards per attempt. The Giants’ run game ended with 135 yards on 28 attempts (4.8 yards per carry), while their pass defense struggled, allowing a completion rate of 73.1% and 343 yards on 38 of 52 passing. New York finished with 506 total yards on 62 plays (8.2 yards per play) and rushed for 84 yards on 21 carries, averaging 4.0 yards per attempt.

The Giants currently average 368.5 yards of offense per game, ranking them 6th in the league. They are recording about 79.0 rushing yards per game, with a total of 158 rushing yards this season. The team has achieved 24 first downs and committed 20 penalties, ranking them 5th in the NFL for unnecessary mistakes. In total, they have recorded 579 passing yards, averaging 289.5 passing yards per game, which puts them at the top of the league. When it comes to scoring, the Giants are averaging 21.5 points per game, placing them 19th in the NFL.

Defensively, the Giants allow an average of 30.5 points per game, ranking them 27th overall. They have surrendered 3 passing touchdowns and average 277.5 passing yards per game, resulting in their 29th rank in the league. New York has allowed a total of 355 rushing yards (177.5 yards per game), along with 4 rushing touchdowns this season. The Giants’ defense has been deployed on the field for 148 plays, placing them 31st in the league. They have achieved 1 turnover and conceded a cumulative 61 points throughout the season.

Who will emerge victorious in this Chiefs-Giants NFL matchup?

Selection: Back the Chiefs -5.5

Some links on this page are affiliate links. If you sign up or make a purchase through them, we may earn a small commission always at no extra cost to you. Thanks for helping us keep this site running.

Pick: Kansas City Chiefs -5.5
Bet Now

Leave a Reply

Your email address will not be published. Required fields are marked *

New Bookmakers
Bet99

Proud Partner of the NHL + Excellent live betting

 

Betway

Widest Range of Betting Options + Robust in-play with streaming

BetMGM

Top-Rated Betting App in Ontario with Live streaming & Cash-out

Sports Interaction

Crafted for Canada’s Bettors. Best Odds For NHL, CFL & NFL

© 2025 BettingEdge.ca. All Rights Reserved. BettingEdge.ca is your trusted source for Canadian sportsbook reviews, betting tips, and responsible gaming resources. Must be 19+ to bet. Play responsibly.