Los Angeles Rams vs Arizona Cardinals Prediction for 12/7/2025 NFL Picks, Best Bets & Odds Week 14

Home » Los Angeles Rams vs Arizona Cardinals Prediction for 12/7/2025 NFL Picks, Best Bets & Odds Week 14

  • Matchup: Los Angeles Rams vs Arizona Cardinals
  • Date: Sunday, December 7, 2025
  • Venue: State Farm Stadium, Glendale, AZ
  • Broadcast: FOX
  • Odds-Point Spread: Cardinals (+8)
  • Total-Over-Under: 48.5

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The Los Angeles Rams (9-3) are heading to State Farm Stadium this Sunday to face off against the Arizona Cardinals (3-9). Setting the stage, Los Angeles is favored by 8 points according to bookmakers, with the total set at 48.5.

The Rams enter the game boasting a 9-3 record for the season. In their most recent encounter, they suffered a narrow defeat against the Carolina Panthers with a final score of 31-28. Blake Corum led the rush for the Rams, achieving 81 yards on 7 carries (averaging 11.6 yards per carry). Xavier Smith showcased his skills, averaging 27.3 yards per catch with 82 yards from 3 receptions. Matthew Stafford completed 18 of 28 passes for 243 yards, tossing 2 touchdowns but also recording 2 interceptions, resulting in a quarterback rating of 85.9. Defensively, the Rams allowed 164 rushing yards on 40 attempts, averaging 4.1 yards per rush. Additionally, they permitted 15 completions on 20 attempts for 194 yards, reflecting a completion percentage of 75.0%. In total, Los Angeles managed 49 offensive plays for 379 yards, with 152 rushing yards on 21 carries, averaging 7.2 yards per attempt.

NFL Predictions Puka Nacua Los Angeles Rams Odds

Throughout the season, the Rams have amassed a total of 4,321 yards. They have achieved 160 first downs and accumulated 52 penalties, adding up to 426 lost yards. On the offensive front, Los Angeles has scored 32 passing touchdowns along with 10 rushing touchdowns, having committed 11 turnovers (4 interceptions and 7 fumbles). Their running game averages 113.5 yards, ranking 19th in the league, and they consistently score an average of 27.8 points per game.

Defensively, the Rams have given up 2,487 passing yards, ranking them 13th in the NFL. They allow 207.3 passing yards per game with a completion rate of 64.4%. Overall, they have yielded 1,294 rushing yards across 12 games this season, allowing 16 touchdowns through the air and 4 on the ground. They rank 13th in total defense, permitting an average of 315.1 yards per game. Opponents average 3.9 yards per carry, totaling 107.8 rushing yards per game. The Rams are particularly effective in limiting scoring, ranking 2nd in the league with just 17.5 points allowed per game.

The Cardinals come into this matchup with a record of 3-9. In their last outing, they faced off against the Tampa Bay Buccaneers, narrowly losing 20-17. Quarterback Jacoby Brissett threw for 301 yards on 29 completions from 40 attempts, achieving 2 touchdowns and a quarterback rating of 100.1, alongside 1 interception and an average of 7.5 yards per throw. Zonovan Knight was strong in the running game with 62 yards from 11 carries, averaging 5.6 yards per rush. Trey McBride shined as the leading receiver, securing 8 catches for 82 yards (averaging 10.3 yards per catch). The Cardinals averaged 5.0 yards per carry, totaling 95 rushing yards on 19 attempts, and ended the game with 386 total yards across 59 plays (6.5 yards per play). On defense, they allowed a completion percentage of 64.3%, giving up 184 passing yards on 18 completions from 28 attempts, while surrendering 95 rushing yards on 27 attempts (3.5 yards per carry).

In terms of scoring ability, the Cardinals rank 20th in the NFL, averaging 22.1 points per game. For the season, they have accrued 2,840 passing yards, averaging 236.7 yards per game, which puts them 8th in the league. Arizona averages 100.6 rushing yards per game, totaling 1,207 yards so far. They rank 16th in total offense with an average of 337.3 yards per game. The Arizona offense has incurred 656 yards from 89 penalties, landing them 8th in the league for yardage penalties. They have thrown 7 interceptions and lost 8 fumbles, successfully achieving 156 first downs on the offensive end.

The Cardinals defense allows 25.3 points per game, ranking 24th in the league. They have surrendered 17 passing touchdowns, allowing 219.6 passing yards per game, ranking 21st in the NFL. On the ground, they have given up 1,351 rushing yards (112.6 yards per game), along with 12 rushing touchdowns throughout the season. The defense has participated in 742 plays from scrimmage, ranking 15th in the league. In terms of turnovers, they have recorded 17 takeaways this season (8 forced fumbles and 9 interceptions), and collectively, they have allowed 303 points.

Who will emerge victorious in tonight’s Rams-Cardinals matchup against the spread?

My Pick: Choose the Cardinals +8

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Pick: Arizona Cardinals +8
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