Louisville Cardinals vs Cincinnati Bearcats Betting Predictions for College Basketball on 11/21/2025

Home » Louisville Cardinals vs Cincinnati Bearcats Betting Predictions for College Basketball on 11/21/2025

  • Matchup: Louisville Cardinals vs Cincinnati Bearcats
  • Date: Friday, November 21, 2025
  • Venue: Heritage Bank Center, Cincinnati, OH
  • Broadcast: ESPN+

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The unbeaten Cincinnati Bearcats (4-0) will face off against the undefeated Louisville Cardinals (4-0) at Heritage Bank Center this Friday.

College Basketball Predictions for Louisville Cardinals

In their most recent match, the Louisville Cardinals dominated Ohio, securing a 106-81 triumph. The Cardinals committed 25 personal fouls compared to Ohio’s 20. From beyond the arc, Louisville converted 9 of 26 shots, while Ohio shot well from the free-throw line, making 20 of 26 attempts for a 76.9% success rate. Ohio pulled down a total of 31 rebounds (11 offensive, 20 defensive) but failed to log any blocks. They also recorded 12 assists and 9 steals during the game. Defensively, Louisville allowed their opponents to shoot 44.1% from the field (26 of 59). The Cardinals achieved 23 assists and forced their opponents into 15 turnovers while picking up 11 steals. Louisville amassed a total of 39 rebounds, with 16 on the offensive board, and shot 73.3% from the free-throw line (22 of 30). The Cardinals finished the contest with a 50.0% field goal percentage (34 of 68) and made 16 out of their 35 three-point attempts.

Ryan Conwell was a standout player, finishing the game with 22 points on 7 of 14 shooting, along with 3 assists and 6 rebounds in 27 minutes of play.

Louisville enters this game with a perfect 4-0 record this season. The Cardinals average only 11.0 turnovers and commit around 20.8 fouls per game. They are collecting 44.3 boards per game and have delivered 90 assists this year, ranking 43rd nationally in assists. Louisville boasts a three-point shooting percentage of 36.4% (51 of 140) and hits 73.6% from the free-throw line. They are scoring an impressive 103.0 points per game, placing them 2nd in Division 1 and shooting 50.0% overall.

Defensively, the Cardinals force their opponents into 17.0 turnovers per game while averaging 22.0 fouls. They rank 38th in Division 1 for assists allowed, having surrendered 41 assists this season. Their defensive shooting percentage stands at 38.9% (96 of 247), allowing 34.5 rebounds per game, and they give up 32.1% on three-point shots, ranking 149th nationally in points allowed per game (71.0).

In their last outing, the Cincinnati Bearcats secured a 72-55 victory over Mount St. Mary’s. The Bearcats grabbed 29 defensive rebounds and 14 offensive boards, totaling 43 in the game. They turned the ball over 10 times but managed to steal the ball 8 times during the match. Mount St. Mary’s committed 23 fouls, leading to 30 free-throw attempts for the Bearcats, who converted 18 for a 60.0% free-throw rate. Cincinnati made 6 out of 29 three-point attempts (20.7%) and finished shooting 24 out of 64 for a rate of 37.5%. The Bearcats allowed Mount St. Mary’s to shoot 21 of 56 (37.5%) from the field and finished 37.0% from three-point range with 10 of 27, while they struggled with free throws, converting only 3 out of 10 (30.0%). Cincinnati permitted Mount St. Mary’s to grab 34 rebounds (6 offensive).

Day Day Thomas significantly contributed to the win, shooting 4 out of 6 (66.7%) and collecting 5 rebounds while scoring 16 points in 26 minutes, also tallying 5 assists.

Cincinnati holds a perfect 4-0 record this season. Offensively, they are making 44.3% of their shots, ranking 226th nationally. So far, the Bearcats have amassed 314 points (78.5 per game) and pull down an average of 41.3 rebounds. They dish out 16.5 assists per game, ranking 123rd in the nation, while averaging 16.3 turnovers and committing 18.0 personal fouls per game, hitting 63.4% from the charity stripe.

On the defensive front, the Bearcats rank 18th in the nation for points allowed per game (61.0) and regularly force their opponents into 17.8 turnovers. Opponents shoot just 35.6% against them (16th in college), while the Bearcats allow 27.0% shooting from beyond the arc. Their opponents convert 68.1% of their free-throw attempts. Cincinnati’s defensive stats include allowing 12.0 assists and 35.3 rebounds per game, ranking 131st and 192nd nationally, respectively.

Who will emerge victorious in tonight’s NCAA matchup against the spread?

Prediction: Take Cincinnati

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Pick: Cincinnati Bearcats
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