Michigan Wolverines vs Nebraska Cornhuskers Prediction for 9/20/2025: College Football Picks, Best Bets & Odds

Home » Michigan Wolverines vs Nebraska Cornhuskers Prediction for 9/20/2025: College Football Picks, Best Bets & Odds

Matchup: Michigan Wolverines vs Nebraska Cornhuskers

Date: Saturday, September 20, 2025

Venue: Memorial Stadium, Lincoln, NE

Broadcast: CBS Paramount+

Betting Line: Cornhuskers (+2.5)

Over-Under: 45

On Saturday, September 20, 2025, the Nebraska Cornhuskers (3-0) will face off against the Michigan Wolverines (2-1) at Memorial Stadium. The Wolverines enter this game as 2.5-point favorites, with an over/under set at 45 points.

Looking at the Wolverines, they currently hold a 2-1 record for the season. Their most recent game saw them dominate the Central Michigan Chippewas with a decisive 63-3 victory. In that match-up, Michigan executed 55 rushing attempts resulting in 381 yards, averaging an impressive 6.9 yards per carry. They completed 80 total plays, accumulating 616 yards offensively. Defensively, Michigan allowed 11 completions out of 20 attempts, yielding just 60 passing yards for a completion rate of 55.0%. Against the run, they conceded 79 yards on 33 attempts, averaging 2.4 yards per carry.

Carter Nelson Nebraska Cornhuskers predictions and betting odds

This season, the Wolverines have tallied 1,356 total yards. On the offensive front, they have scored 2 touchdowns through the air and 12 on the ground, with a total of 2 turnovers. Michigan’s offensive line has produced 67 first downs, while their discipline has led to 15 penalties for 142 yards. Their rushing game averages 242.7 yards per game, placing them 15th in Division 1, and they score an impressive average of 36.7 points per game.

However, defensively, the Wolverines have allowed 547 passing yards this season, ranking 50th nationally. They give up an average of 182.3 passing yards per game with a completion percentage of 62.6%. Overall, their defense has surrendered 271.3 yards per game, ranking them 33rd. With 3 passing touchdowns and 2 rushing touchdowns allowed, their rushing defense averages 2.6 yards per attempt and 89 rushing yards per game, totaling 267 rushing yards given up across 3 games. Michigan sits 33rd in the country regarding opponent scoring, allowing 14.7 points per game.

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The Nebraska Cornhuskers come into this game undefeated at 3-0. In their last game, Nebraska triumphed over the Houston Christian Huskies with a significant win of 59-7. In that contest, the Cornhuskers averaged 5.1 yards per carry, amassing 192 yards on 38 attempts and concluding the game with a total of 554 offensive yards from 67 plays, averaging 8.3 yards per play. Defensively, Nebraska’s passing defense allowed a completion percentage of 61.1%, giving up 67 yards on 11 completions out of 18 attempts. They held the opposing rush game to 93 yards on 35 attempts, averaging 2.7 yards per carry.

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Currently, the Cornhuskers average 545.0 yards per game, positioned 10th in Division 1. Nebraska’s offense has incurred 143 yards through 13 penalties, ranking them 107th in Division 1 in terms of aiding their opponents. They average 178.7 rushing yards per game, totaling 536 rushing yards so far this season. Their efficiency is highlighted by zero interceptions thrown and only one fumble lost, while they have secured 84 first downs. Offensively, they are 9th in Division 1, scoring an average of 49.0 points per game. Thus far, they have accumulated 1,099 passing yards, averaging 366.3 passing yards per game, placing them 5th in the nation.

Nebraska has given up a total of 408 rushing yards (136.0 yards per game), along with 3 rushing touchdowns this season. Impressively, they have yet to concede a touchdown through the air, limiting opponents to 66.0 passing yards per game, leading all of Division 1 in this category. This season, they have allowed only 24 points, with 4 fumbles recovered and 1 interception. The Cornhuskers have played 167 defensive snaps, placing them at 29th in Division 1. They are yielding just 8.0 points per game, which ranks them 7th nationally.

Who will emerge victorious in this Wolverines vs Cornhuskers college football clash against the spread?

Tony’s Prediction: Choose the Wolverines -2.5

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