Milwaukee Brewers vs Chicago Cubs Forecast, 8/20/2025 MLB Predictions, Top Picks & Odds

Home » Milwaukee Brewers vs Chicago Cubs Forecast, 8/20/2025 MLB Predictions, Top Picks & Odds

Matchup: Milwaukee Brewers vs Chicago Cubs

Event Date: Wednesday, August 20, 2025

Venue: Wrigley Field, Chicago, IL

Broadcast: Marquee

Betting Odds: Milwaukee (-132) Chicago (+110)

The Milwaukee Brewers (79-45) are set to face off against the Chicago Cubs (70-54) at Wrigley Field this Wednesday. Betting lines show Milwaukee at -132 and Chicago at +110, with an over/under total of 9 runs. Anticipated starting pitchers are Jacob Misiorowski and Colin Rea.

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The Milwaukee Brewers lead the league with an impressive average of 5.2 runs per game. Their season total of 645 runs scored is complemented by an on-base percentage of .333. The team has achieved 196 doubles and hit 134 home runs, recording 598 RBIs and 1,091 total hits this year, boasting a batting average of .259. The Brewers have a slugging percentage of .407, with 979 strikeouts and 429 walks.

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The Brewers have a stellar team earned run average (ERA) of 3.56 this season (ranked 2nd in MLB), with 1,077 batters struck out. Their pitchers have allowed 134 home runs and have given up a total of 477 runs (3rd in the league). With a walk count of 410 and a FIP of 3.98, Milwaukee has permitted 946 hits (7.7 per 9 innings) and 438 earned runs. Their strikeout-to-walk ratio stands at 2.63, coupled with a WHIP of 1.23.

The Brewers’ bullpen boasts a save percentage of 72.0%, participating in 140 save situations. Relief pitchers have inherited 167 base runners this season, with a 31.7% scoring rate. They have confronted 111 situations with runners on base and taken the mound in 142 high-pressure scenarios. The Brewers have utilized 425 relievers, achieving 86 holds this season (3rd in MLB) and securing 36 saves with 14 blown opportunities.

The team has tallied 3,320 putouts, alongside 1,005 assists and 57 errors. Their fielding percentage of .987 places them 11th in MLB, having turned 88 double plays. The Brewers convert 71.4% of batted balls into outs across 9,960 innings, ranking them 3rd in the league.

Misiorowski has pitched for 34 innings, accumulating 50 strikeouts in his professional career. His ERA stands at 3.95, allowing 15 earned runs with a WHIP of 1.140, while permitting 22 hits (5.8 hits per nine innings) and handing out 17 free passes. Misiorowski holds a career record of 4-1 and shows a FIP of 3.89, having faced 140 hitters in the majors.

The Chicago Cubs have posted an on-base percentage of .319 and a team batting average of .250 this season. They rank 27th in the league with 958 strikeouts and have tallied 1,059 hits. With 170 home runs and 598 RBIs, the Cubs’ slugging percentage stands at .429, scoring an average of 4.95 runs per game (5th in MLB). They have hit 204 doubles and drawn 416 walks, scoring 614 total runs.

The Cubs’ pitching unit has allowed 504 runs, maintaining an overall ERA of 3.84 (469 earned runs). They’ve conceded 153 home runs and allow 4.12 runs per 9 innings (6th in MLB). With a WHIP of 1.206 and a FIP of 4.19, they possess a K/BB ratio of 7.70 (945 strikeouts against 320 walks) and rank 12th in total hits allowed with 1,007.

In terms of save situations, the Cubs have recorded 78 holds and 14 blown saves from 124 save opportunities. Their bullpen pitchers have taken the mound in 43 save chances with a total of 29 saves, participating 118 times in high-pressure situations and facing runners in 83 instances. Their inherited score percentage stands at 29.7% from 118 inherited base runners, ranking them 7th in the league with a save rate of 67.4%, utilizing 405 bullpen pitchers this season.

Defensively, the Chicago Cubs have managed 95 double plays, showcasing a .988 fielding percentage (7th in MLB). They have recorded 1,037 assists, 52 errors, and 3,302 putouts throughout the season. In 9,906 innings, they display a defensive efficiency of 71.4% (4th in MLB).

Rea (career record of 35-25) carries a 4.46 ERA and allows 8.8 hits per 9 innings. With a strikeout to walk ratio of 2.67, he has faced 2,414 batters in his MLB career, surrendering 281 earned runs. He has a WHIP of 1.280 and a FIP of 4.4, allowing 555 hits and achieving 456 strikeouts over 567 innings.

Who will emerge victorious in tonight’s MLB showdown against the spread or moneyline?

Josh Schonwald’s Prediction: Back Milwaukee (-132)

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