Matchup: Milwaukee Brewers vs. St. Louis Cardinals
Scheduled Date: Saturday, September 20, 2025
Venue: Busch Stadium, St. Louis, MO
Broadcast: FanDuel Sports Network Midwest
Betting Odds: Milwaukee (-132) St. Louis (+110)
The St. Louis Cardinals (74-79) take on the Milwaukee Brewers (93-59) at Busch Stadium this Saturday. The moneyline for this game features Milwaukee at -132 and St. Louis at +110. The over/under is set at 8 runs. Expected starters are Chad Patrick for Milwaukee and Miles Mikolas for St. Louis.


The Milwaukee Brewers boast a slugging percentage of .409, having struck out 1,185 times while drawing 528 walks. They have accumulated 724 RBIs and 1,348 hits throughout the season, maintaining a batting average of .261. The Brewers have recorded 248 doubles and blasted 162 home runs. With a team on-base percentage of .334, Milwaukee averages 5.1 runs per game, ranking 2nd in Major League Baseball.
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The Brewers currently hold an impressive team ERA of 3.61, placing them 2nd in MLB. Their pitching staff has recorded 1,345 strikeouts, allowed 158 home runs, and given up a total of 593 runs, which ranks 3rd in the league. They’ve issued 500 walks and sport a FIP of 3.92. Milwaukee has allowed 1,157 hits (7.7 per 9 innings) and given up 542 earned runs, posting a strikeout-to-walk ratio of 2.69 along with a WHIP of 1.23.
This season, Brewers’ relievers have entered with runners on base 133 times and have appeared 170 times in critical game situations. The bullpen has achieved 100 holds (ranked 5th in baseball) and maintains a save rate of 68.9%, having secured 42 saves against 19 blown opportunities out of 61 chances. The total number of inherited runners stands at 197, with a 30.5% scoring rate for inherited runners. Milwaukee has utilized 513 relief pitchers so far this year.
In the field, the Milwaukee Brewers have made 4,058 putouts, contributed 1,207 assists, and committed 69 errors, achieving a fielding percentage of .987, ranking 10th in the MLB. They have managed 111 double plays and converted 71.0% of balls put in play into outs over 12,174 innings, placing them 4th in professional baseball.
Chad Patrick has pitched 111 innings in his career, striking out 116 batters, and holding a career ERA of 3.65 (45 earned runs allowed) with a WHIP of 1.287. He’s yielded 106 hits (8.6 hits per nine innings) along with 37 walks. Patrick has a career record of 3-8 and a FIP of 3.59, having faced 469 batters throughout his tenure in the majors.
The St. Louis Cardinals exhibit a team slugging percentage of .378, averaging 4.27 runs per game (21st in the league). They have hit 243 doubles, drawn 451 walks, and compiled 653 RBIs, with 142 home runs recorded this season. St. Louis has struck out 1,240 times (21st in the league) and registered a total of 1,255 hits, with a team on-base percentage of .314 and a batting average of .244 for the year.
The Cardinals’ pitching staff reports a WHIP of 1.320 and a FIP of 4.04. Their K/BB ratio is 7.50 (1,135 strikeouts against 438 walks), ranking 26th in MLB for total hits allowed at 1,349. They’ve surrendered 156 home runs and allow 4.73 runs per 9 innings (22nd in the league), with an overall ERA of 4.29 (645 earned runs allowed).
The Cardinals’ bullpen has faced 152 save opportunities, obtaining 86 holds but also encountering 22 blown saves. St. Louis relief pitchers have been called upon in 62 save situations, converting 40 saves. They have made 148 high-leverage appearances with runners on base, resulting in a 33.0% rate of inherited runners scoring. Their save rate stands at 64.5%, ranking 12th in the league, with 456 total relief pitchers used this season.
In their 12,186 innings played, St. Louis holds a defensive efficiency of 69.0% (22nd in MLB), notching 121 double plays and a fielding percentage of .987 (13th in the majors). They have achieved 1,465 assists, committed 75 errors, and recorded 4,062 putouts.
Throughout his MLB career, Miles Mikolas has yielded 1,266 hits while striking out 888 batters over 1,242 innings. With a WHIP of 1.215 and a FIP of 4.2, he has allowed 584 earned runs. His K/BB ratio stands at 3.65, having faced 5,174 opposing hitters to date. Mikolas has a career win-loss record of 72-74 and holds a 4.23 ERA with 9.2 hits allowed per nine innings.
Who will triumph tonight in the MLB matchup—against the spread or on the moneyline?
Guy Bruhn’s Selection: St. Louis (+110)
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