- Matchup: Missouri Tigers vs. Oklahoma Sooners
- Scheduled Date: Saturday, November 22, 2025
- Venue: Memorial Stadium, Norman, OK
- Broadcast: ABC
- Betting Odds: Sooners favored by 7.5 points
- Over/Under Total: 42.5 points
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The Oklahoma Sooners (8-2) will host the Missouri Tigers (7-3) on Saturday, November 22, 2025, at Memorial Stadium. According to Las Vegas bookmakers, the Sooners are the 7.5-point favorites, with the total set at 42.5 points.
Entering this matchup, the Missouri Tigers hold a 7-3 record for the season. Their most recent game saw them triumph over the Mississippi State Bulldogs, winning 49-27. On the ground, Missouri allowed 243 rushing yards on 39 attempts, averaging 6.2 yards per carry. The Tigers’ defense surrendered 20 completions on 29 attempts for 221 yards, resulting in a completion rate of 69.0%. By the end of the game, they had executed 55 plays netting a total of 438 yards. Offensively, Missouri ran the ball 39 times for 326 yards, resulting in an impressive average of 8.4 yards per attempt.

Scoring-wise, the Missouri Tigers average an impressive 34.9 points per game. Their rushing attack is ranked 6th in Division 1, accumulating 241.7 yards per outing. Overall, Missouri has amassed 4,504 total yards this season. In terms of touchdowns, they have recorded 15 through the air and 27 on the ground. The Tigers have achieved 241 first downs but faced 55 penalties totaling 529 yards. Turnover-wise, they have turned the ball over 13 times.
With regard to defense, the Tigers rank 26th nationally, allowing 19.9 points per game. They permit an average of 3.4 yards per carry, with opposing teams gaining 107.6 rushing yards per game over the season, totaling 1,076 yards throughout 10 contests. In passing defense, they’ve given up 1,699 yards, holding an average of 169.9 yards per game, ranking them 14th nationally, with a completion percentage of 56.6%. Overall, their defense allows 277.5 yards per game, placing them 10th in the country. They have conceded 12 touchdown passes and 11 rushing touchdowns this season.
The Sooners enter this game with an 8-2 record for the current season. In their previous outing, they secured a narrow 23-21 victory over the Alabama Crimson Tide. On the ground, Oklahoma averaged 2.6 yards per carry, accumulating 74 yards on 28 attempts. The team generated a total of 212 yards over 51 plays, averaging 4.2 yards each time they had the ball. In pass defense, the Sooners allowed a completion rate of 64.4%, giving up 393 yards on 29 of 45 passing attempts. They limited opponents to 63 rushing yards on 35 carries, allowing just 1.8 yards per attempt.
Oklahoma’s offense averages 357.5 yards per game, ranking 89th in college football. They have amassed a total of 605 penalty yards across 68 infractions, ranking 43rd in Division 1 in this category. The rushing game averages 130.7 yards per game, having totaled 1,307 rushing yards thus far. The Sooners have thrown 7 interceptions and lost 5 fumbles while achieving 194 first downs. In terms of scoring, the Sooners rank 63rd nationally, averaging 28.3 points per game. They have passed for a total of 2,268 yards, averaging 226.8 yards per game, placing them 71st in the nation.
Defensively, Oklahoma allows an average of 14.8 points per game, ranking 8th in the country. They have given up 822 rushing yards (82.2 yards per game), conceding 6 touchdowns on the ground this season. In passing defense, the Sooners have allowed 8 touchdown passes and an average of 196.2 yards per game, putting them 37th nationally. The defense has participated in 647 plays this year, ranking 40th in the nation, with 4 fumbles and 6 interceptions recorded. They have allowed a total of 148 points this season.
Who will come out on top in this exciting college football clash between the Tigers and Sooners?
Prediction: Bet on the Tigers +7.5
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