New York Yankees vs San Francisco Giants Prediction MLB Picks, Best Bets & Odds for 3/28/2026

Home » New York Yankees vs San Francisco Giants Prediction MLB Picks, Best Bets & Odds for 3/28/2026

  • Game: New York Yankees vs San Francisco Giants
  • Date: Saturday, March 28, 2026
  • Location: Oracle Park, San Francisco, CA
  • TV: NBC Bay Area
  • Odds/Point Spread: New York Yankees (-275) San Francisco Giants (+220)

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The New York Yankees (94 wins, 68 losses last season) are heading to Oracle Park this Saturday to face off against the San Francisco Giants (81 wins, 81 losses in the last season). In this matchup, the Yankees are favored with a moneyline of -275, while the Giants come in at +220. The total for betting is set at 9 runs. The starting pitchers expected for this game are Will Warren and Tyler Mahle.

MLB expert predictions for San Francisco Giants

Last season, the Yankees showcased a slugging percentage of .455, with a total of 1,463 strikeouts and 639 walks taken. They achieved 820 RBIs and secured 1,371 hits, concluding the season with a batting average of .251. The team hit 255 doubles and smashed 274 home runs, accumulating 849 runs and a .332 on-base percentage. Collectively, the New York Yankees averaged 5.2 runs per game, placing them at the top of MLB.

The Yankees recorded a K/BB ratio of 2.59, and their pitching staff ended with a WHIP of 1.25. Last season, Yankees pitchers allowed 175 home runs and 685 runs (15th in MLB). They conceded 1,239 hits (averaging 7.7 per 9 innings) and 625 earned runs, finishing the year with a team ERA of 3.91 (14th in MLB) and notching 1,440 strikeouts. The pitching staff walked 557 batters, with a FIP of 4.00.

Throughout last season, the Yankees utilized 533 relief pitchers. The bullpen inherited 255 runners, with 27.5% of those scoring. They registered 43 saves from 64 save opportunities, yielding a save percentage of 67.2% in 166 high-leverage situations. Last season, the Yankees’ bullpen successfully held 100 games (9th in league standings).

Defensively, the Yankees achieved 4,319 putouts, 1,389 assists, and committed 94 errors, resulting in a fielding percentage of .986, placing them 13th in MLB. They completed 105 double plays and converted 70.8% of balls in play into outs over 12,957 innings, ranking them 6th overall in professional baseball.

Will Warren brings 184 innings of experience to the mound, amassing 200 strikeouts in his career. With a career record of 9 wins and 11 losses, Warren has a FIP of 5.10 and an ERA of 5.18, allowing 106 earned runs. His WHIP stands at 1.443, having given up 191 hits with an average of 9.3 hits per nine innings and 75 walks.

The San Francisco Giants, last season, reported an on-base percentage of .311 and a batting average of .235. They struck out 1,380 times (12th in league) and totaled 1,261 hits. Scoring 672 runs, they homered 173 times and achieved a team slugging percentage of .386 while averaging 4.35 runs per game (17th in the league). They also recorded 239 doubles and 556 walks, totaling 705 runs.

The Giants posted a WHIP of 1.298, with a FIP of 3.74, ranking 21st in the league for total hits allowed with 1,354. The pitching staff conceded 684 runs, producing an overall team ERA of 3.84 alongside 612 earned runs. Their K/BB ratio stood at 8.50 (1,358 strikeouts against 506 walks), allowing 143 home runs and giving up 4.30 runs per 9 innings (15th in league).

In 152 save opportunities, the Giants recorded 89 holds but blew 22 saves. They relied on their relievers in 63 save chances, securing 41 saves. Pitchers entered high-pressure situations 173 times and faced base runners on 122 occasions. The inherited runners’ score rate was 36.8%, with the bullpen ranked 10th in save percentage at 65.1%, having utilized 515 relief pitchers over the course of the season.

Defensively, the Giants yielded a defensive efficiency of 68.4% (26th in majors), recorded 134 double plays, and concluded with a fielding percentage of .984 (23rd in MLB). They tallied 1,523 assists, committed 95 errors, and achieved 4,301 putouts last season.

On an individual note, Tyler Mahle has allowed 681 hits, while collecting 753 strikeouts in 734 innings pitched throughout his MLB career. His WHIP stands at 1.287, with a FIP of 4.00 and an earned run average of 4.07, allowing 332 earned runs while facing 3,122 batters. His career record is 39 wins against 46 losses, yielding an average of 8.3 hits per nine innings.

Who will emerge victorious in tonight’s MLB clash, against the spread or moneyline?

Recommendation: Select San Francisco (+220)

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Pick: San Francisco Giants (+220)
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