Rutgers Scarlet Knights vs Purdue Boilermakers Prediction for 10/25/2025 College Football Picks, Best Bets & Odds

Home » Rutgers Scarlet Knights vs Purdue Boilermakers Prediction for 10/25/2025 College Football Picks, Best Bets & Odds

  • Matchup: Rutgers Scarlet Knights vs Purdue Boilermakers
  • Date: Saturday, October 25, 2025
  • Venue: Ross-Ade Stadium, West Lafayette, IN
  • Broadcast: BTN
  • Betting Odds/Point Spread: Boilermakers (+2.5)
  • Game Total/Over-Under: 59

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The Rutgers Scarlet Knights (3-4) are gearing up for an away game at Ross-Ade Stadium on Saturday, October 25, 2025, aiming for a victory against the Purdue Boilermakers (2-5). The Knights enter this contest favored by 2.5 points, with a total set at 59.

With a season record of 3-4, the Scarlet Knights recently faced a tough defeat against the Oregon Ducks, losing 56-10. In that game, they executed 69 plays for a total of 202 yards. On the ground, Rutgers managed 123 yards from 42 carries, averaging 2.9 yards per rush. However, their defense struggled against Oregon’s rushing attack, conceding 415 yards on 37 attempts, which translates to an alarming average of 11.2 yards per carry. In the passing game, they allowed 18 completions from 24 attempts, yielding 335 yards at a completion rate of 75.0%.

college football predictions Devin Mockobee Purdue Boilermakers best odds and bets

Throughout the season, the Scarlet Knights have accumulated 2,865 total yards. In terms of scoring, they have secured 13 touchdowns through the air and another 13 on the ground, while turning the ball over 6 times. Rutgers has recorded 174 first downs and incurred 31 penalties totaling 241 yards. Averaging 133.1 rushing yards per game, they currently rank 95th in the nation. Offensively, the Knights average 32.0 points per game.

On the defensive front, Rutgers ranks 119th in FBS, allowing an average of 31.6 points per game. They concede approximately 6.0 yards per rush and 176.1 rushing yards per game, having given up 1,233 yards on the ground over 7 games. In terms of pass defense, they have allowed 1,829 yards, ranking 123rd overall, with an average of 261.3 passing yards allowed per game and a completion percentage of 67.4%. Overall, they relinquish 437.4 total yards per game, placing them 123rd in the nation, with 12 touchdown passes and 16 rushing touchdowns allowed.

The Boilermakers enter this matchup with a 2-5 record for the season. In their previous game, Purdue faced a shutout loss against the Northwestern Wildcats, with a final score of 19-0. The Boilermakers generated 305 yards from 56 plays, averaging 5.4 yards per play. Their rushing attack managed 87 yards on 26 carries, averaging 3.3 yards per rush. Defensively, Purdue allowed 232 rushing yards on 50 attempts (4.6 yards per carry) and yielded a completion rate of 42.3%, giving up 132 yards on 11 completions from 26 attempts.

Purdue’s offense averages 393.9 yards per game, sitting at 66th in FBS. They have accumulated 420 penalty yards over 42 infractions, placing them 77th in the country. Their ground game averages 130.9 yards per game, having gained 916 yards overall. The Boilermakers have struggled with turnovers, throwing 10 interceptions and losing 5 fumbles, but have managed to produce 156 first downs. In scoring, they average 22.7 points per game, ranking 100th in college football. They have totaled 1,841 passing yards, with an average of 263.0 passing yards per game, ranking 43rd nationally.

Defensively, Purdue allows 27.9 points per game, placing them 96th in FBS. They have given up a total of 1,008 rushing yards (144.0 yards per game) along with 11 rushing touchdowns this season. Their pass defense has allowed 8 touchdowns and 229.4 yards per game, ranking 84th in college football. The Boilermakers have participated in 445 defensive plays, ranking 48th in FBS, achieving 2 fumble recoveries and 2 interceptions. So far this season, they have given up a total of 195 points.

Who will secure the win in this enticing Scarlet Knights vs Boilermakers college football matchup against the spread?

Expert Pick: Take the Boilermakers +2.5

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Pick: Purdue Boilermakers +2.5
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