- Matchup: San Francisco 49ers vs Los Angeles Rams
- Date: Thursday, October 2, 2025
- Venue: SoFi Stadium in Inglewood, CA
- Broadcast: Prime Video
- Betting Odds: Rams favored by 5.5 points
- Over/Under: 47
This page may include affiliate links at no extra cost to you, thanks for your support.
The San Francisco 49ers (3-1) will face off against the Los Angeles Rams (3-1) at SoFi Stadium this Thursday. The Rams open as 5.5-point favorites according to Las Vegas bookmakers, with the total set at 47 points.
The 49ers come into this weekend with a 3-1 record. In their previous outing, they faced off against the Jacksonville Jaguars but suffered a narrow defeat, 26-21. Quarterback Brock Purdy completed 22 of 38 passes for 309 yards and 2 touchdowns, earning a quarterback rating of 79.8, although he did throw 2 interceptions. Christian McCaffrey stood out as the team’s leading receiver, catching 6 passes for 92 yards with an impressive average of 15.3 yards per catch. As a runner, McCaffrey had 17 carries for 49 yards, averaging just 2.9 yards per carry. The 49ers ran a total of 62 plays for 389 yards, rushing the ball 24 times for 83 yards at an average of 3.5 yards per attempt. Defensively, the 49ers allowed 151 rushing yards on 32 attempts (4.7 yards per carry) and conceded 21 completions out of 31 attempts for 174 passing yards, achieving a 67.7% completion rate.
When focusing on scoring, the 49ers currently average 20.0 points per game. Their rushing attack has been subpar, totaling 88.0 yards per game, ranking them 28th in the NFL. Over the season, they have amassed a total of 1,472 yards, with 61 first downs and 24 penalties resulting in a loss of 224 yards. Turnovers have been a concern, as they have given the ball away 8 times (5 interceptions and 3 fumbles). On the offensive side, they have recorded 8 passing touchdowns and no rushing touchdowns.
On defense, the 49ers are performing well, ranking 7th in the league by allowing an average of 18.8 points per game. They concede 4.0 yards per carry, totaling 115.5 rushing yards per game. In passing, they have given up 660 yards, ranking 6th in the NFL, averaging 165.0 passing yards per game with a completion rate of 68.3%. Overall, they surrender 280.5 total yards per game, also 6th in the league, yielding 5 passing touchdowns and 2 rushing touchdowns while allowing 462 rushing yards across 4 games this season.
The Los Angeles Rams enter this contest with a 3-1 record as well. In their last game, they earned a 27-20 victory over the Indianapolis Colts. Quarterback Matthew Stafford threw for 375 yards with 3 touchdowns on 29 completions from 41 attempts, achieving a quarterback rating of 123.5 without any interceptions and an average of 9.1 yards per attempt. Kyren Williams contributed significantly, running the ball 13 times for 77 yards, averaging 5.9 yards per carry. Puka Nacua was a key target, catching 13 passes for 170 yards, averaging 13.1 yards per reception. Overall, the Rams rushed for 3.9 yards per carry, accumulating 102 rushing yards on 26 attempts, finishing the game with 462 total yards from 67 plays (6.9 yards per play). Their pass defense allowed a 72.7% completion rate, giving up 248 yards on 24 completions from 33 attempts, while allowing 85 rushing yards on 21 carries (4.0 yards per rushing attempt).
The Rams average 388.3 total yards per game, which ranks them 4th in the league. They have a rushing average of 120.8 yards per game, totaling 483 rushing yards so far. With 50 total first downs, the Rams have been prone to errors, accumulating 22 penalties resulting in 193 total yards lost, placing them 28th in the league for mistakes. In passing, the Rams have gathered 1,070 yards, averaging 267.5 yards per game, which ranks them 3rd in the NFL. In scoring, they sit 13th overall, averaging 25.0 points per game.
Defensively, the Rams allow an average of 20.3 points per game, placing them 10th in the league. They have given up 5 passing touchdowns while conceding an average of 186.0 passing yards per game, which ranks them 10th. In rushing defense, the Rams have allowed a total of 394 yards (98.5 yards per game) and 2 rushing touchdowns this season. With their defense on the field for a total of 240 plays, they rank 14th in the NFL. So far, they have forced 7 turnovers (4 fumbles and 3 interceptions), allowing a total of 81 points.
Who will emerge victorious in tonight’s clash between the 49ers and Rams while beating the spread?
Expert Pick: Consider the 49ers +5.5
Some links on this page are affiliate links. If you sign up or make a purchase through them, we may earn a small commission always at no extra cost to you. Thanks for helping us keep this site running.
