Matchup: San Francisco Giants vs Arizona Diamondbacks
Event Date: Wednesday, September 17, 2025
Venue: Chase Field, Phoenix, AZ
Broadcast: DBACKS.TV
Betting Odds: San Francisco (+125) Arizona (-145)
The San Francisco Giants (75-75) are set to face the Arizona Diamondbacks (76-75) at Chase Field this Wednesday. The current betting odds show San Francisco at +125 and Arizona at -145, with a total of 9 runs anticipated. Justin Verlander and Brandon Pfaadt are expected to take the mound for their respective teams.


San Francisco’s offense boasts a slugging percentage of .388, with 1,275 strikeouts and 508 walks this season. They have amassed 622 RBIs and 1,179 hits, sporting a batting average of .237. The Giants have 222 doubles and have hit 161 home runs, scoring 652 runs with an on-base percentage of .312. Their average runs per game stands at 4.4, placing them 17th in the league.
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San Francisco holds a K/BB ratio of 2.66, and their pitching staff has registered a WHIP of 1.31. They have surrendered 128 home runs along with a total of 637 runs (13th in the league). The Giants have allowed 1,259 hits (8.5 per 9 innings) and 569 earned runs, boasting a team ERA of 3.86 (10th in MLB), while striking out 1,262 hitters. Their pitchers have issued 474 walks, culminating in a team FIP of 3.71 this season.
This year, the Giants have sent 477 relief pitchers to the mound, with 180 inherited runners – 37.8% of whom have scored. The bullpen has recorded 36 saves but has blown 19 of 55 save opportunities, resulting in a 65.5% success rate. The relievers have contributed 79 holds this season (19th in MLB) and have frequently been called upon in close games, entering during 134 save situations. The Giants’ pitchers have faced 113 times with runners on base, participating in 157 high-leverage scenarios.
The Giants have made 3,983 putouts, 1,403 assists, and 88 errors this season, maintaining a fielding percentage of .984, which ranks 24th in MLB. They’ve turned 123 double plays, converting 68.2% of balls in play into outs over 11,949 innings, positioning them 28th in the league.
Verlander has pitched 3,549 innings in his career, accumulating 3,540 strikeouts with an earned run average of 3.32 (1,311 earned runs). His WHIP stands at 1.135, having allowed 3,029 hits (7.7 hits per 9 innings) and issued 999 walks. With a career record of 265-157, Verlander possesses a FIP of 3.27 against a total of 14,534 hitters faced throughout his MLB journey.
The Arizona Diamondbacks have recorded 204 home runs and 730 RBIs this season, along with 257 doubles and 505 walks, totaling 751 runs. Their on-base percentage is .324, coupled with a team batting average of .251. The Diamondbacks hit for a team slugging percentage of .435 and score an average of 4.97 runs per game (5th in MLB). They’ve struck out 1,227 times (17th in MLB) while accumulating 1,280 total hits.
Arizona’s pitching staff holds a WHIP of 1.316 and a team FIP of 4.28 in 2023. Their K/BB ratio is 8.00 (1,195 strikeouts versus 467 walks), ranking them 24th in MLB for hits allowed, giving up 1,302 hits and 180 home runs. They yield 4.83 runs per 9 innings (23rd in the league) and have surrendered 721 runs, resulting in a team ERA of 4.45 (664 earned runs).
With 161 save situations handled, the Diamondbacks have achieved 86 holds with 29 blown saves. Arizona’s bullpen has been tasked in 70 save opportunities, achieving 41 saves. Their relief pitchers have entered in 154 high-pressure situations and have come in when runners are on base 137 times. The inherited runner score percentage stands at 33.3% for 183 inherited base runners. Arizona ranks 22nd in save rate at 58.6%, having utilized 463 relievers this season.
The Diamondbacks have successfully turned 120 double plays and boast a fielding percentage of .986 (15th in MLB). They have logged 1,359 assists, 76 errors, and executed 4,032 putouts throughout the season. Their defensive efficiency stands at 69.6% over 12,096 innings (20th in the majors).
Pfaadt, in his career, has allowed 479 hits across 434 innings, tallying 410 strikeouts. He has given up 249 earned runs with a WHIP of 1.337 and a FIP of 5.1, holding a strikeout-to-walk ratio of 4.02. His career record is 27-27, and his ERA stands at 5.16, allowing 9.9 hits per 9 innings pitched.
Who will prevail in tonight’s MLB matchup against the spread or moneyline?
Expert’s Selection: Choose Arizona (-145) and under 9 runs
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