Game: St. Louis Cardinals vs Milwaukee Brewers
Date: Sunday, September 14, 2025
Location: American Family Field, Milwaukee, WI
Broadcast: FanDuel Sports Network Wisconsin
Odds/Point Spread: St. Louis (+106) Milwaukee (-128)
American Family Field is set to host an exciting matchup this Sunday, where the Milwaukee Brewers (89-58) will face off against the St. Louis Cardinals (72-75). The opening moneyline for this game shows St. Louis at +106 while Milwaukee is at -128. The game total is established at 8.5 runs. Anticipated starting pitchers for this duel are Miles Mikolas and Jacob Misiorowski.
This season, the Cardinals have secured a total of 234 doubles along with 138 home runs. With a slugging percentage of .379, they have struck out 1,185 times and drawn 433 walks. Averaging 4.3 runs per game, the Cardinals rank 22nd in the league, tallying 599 RBIs and 1,206 hits, thus maintaining a team batting average of .244. They have scored a total of 629 runs and hold an on-base percentage of .313.
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St. Louis boasts a team ERA of 4.26 this season, placing them 21st overall, with their pitchers racking up 1,086 strikeouts. The Cardinals’ pitching staff has allowed 151 home runs and 675 runs, ranking 22nd in MLB. They have issued 415 walks and hold a FIP of 4.04. This season, St. Louis has conceded 1,293 hits (9.0 per 9 innings) and 615 earned runs, with a strikeout-to-walk ratio of 2.62 and a combined WHIP of 1.31.
Cardinals pitchers have faced players on base 141 times, with 140 high-leverage situations. The bullpen has secured 82 holds this season (14th in baseball) and a save rate of 65.5%, appearing in 143 save opportunities. They have achieved 38 saves while allowing 20 blown saves. The relief corps have inherited 195 base runners, with a score of 32.8% crossing home plate. Thus far, the Cardinals have utilized 434 relief pitchers throughout the season.
In their 11,706 innings on the field, the Cardinals have converted 69.1% of balls in play into outs, ranking 21st in MLB. The team has recorded 3,902 putouts, 1,414 assists, and 71 errors, achieving a fielding percentage of .987 (11th in the league) along with 116 double plays turned.
Mikolas has logged 1,237 innings, accumulating 883 strikeouts in his professional career. Holding a career record of 71-74, Mikolas has a FIP of 4.17 while facing 5,154 batters. His earned run average stands at 4.23, having allowed 582 earned runs with a WHIP of 1.216. He has given up 1,261 hits (9.2 hits per 9 innings) and has issued 243 walks.
This season, the Milwaukee Brewers have hit 157 home runs while also recording 689 RBIs. They have tallied 239 doubles, walked 504 times, and scored a total of 743 runs, leading to an OBP of .333 and a batting average of .260. The Brewers hold a slugging percentage of .408 and average 5.05 runs per game, ranking them 3rd in the league. They have struck out 1,147 times (25th in MLB) and combined for 1,300 hits.
The Brewers’ pitching staff carries a WHIP of 1.232 and a combined FIP of 3.92. They sit at 3rd in MLB in total hits allowed with 1,124. Milwaukee’s pitchers have surrendered 576 runs this year and maintain a 3.63 ERA (527 earned runs allowed). Their strikeout-to-walk ratio stands impressively at 8.90 (1,290 strikeouts against 485 walks). They have allowed 152 home runs, giving up an average of 3.97 runs per 9 innings, ranking 4th in the league.
Milwaukee’s relievers have a 29.7% inherited score percentage from 192 base runners. Those in high-leverage situations have appeared 169 times, with 129 of those having runners on base. In 165 save situations, the Brewers boast 100 holds and 19 blown saves, ranking them 6th in the league with a save percentage of 68.9%. This season, 494 relief pitchers have been called upon, with 42 successful saves out of 61 save opportunities.
This season, the Brewers have converted 107 double plays, holding a .987 fielding percentage (9th in MLB). They have recorded 1,172 assists, 65 errors, and a total of 3,920 putouts in 11,760 innings played, achieving a defensive efficiency of 70.9% (4th in professional baseball).
Throughout his career, Misiorowski has given up 36 hits, collecting 77 strikeouts over 55 innings. He has allowed 25 earned runs with a WHIP of 1.091 and a FIP of 4.0. His strikeout-to-walk ratio is 3.21 and he has faced 220 hitters, holding a 5-2 career win-loss record and a 4.09 ERA while yielding 5.9 hits per 9 innings pitched.
Who will emerge victorious in this MLB matchup, covering the spread or winning on the moneyline?
Parlay’s Pundit’s Pick: Bet on Milwaukee (-128) and the under 8.5 runs
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