St. Louis Cardinals vs San Diego Padres Prediction for 8/2/2025 MLB Picks, Best Bets and Odds

Home » St. Louis Cardinals vs San Diego Padres Prediction for 8/2/2025 MLB Picks, Best Bets and Odds

Matchup: St. Louis Cardinals vs San Diego Padres

Event Date: Saturday, August 2, 2025

Venue: Petco Park, San Diego, CA

Broadcast: Padres.TV

Betting Odds: St. Louis (+125), San Diego (-145)

The San Diego Padres (60-49) are set to face the St. Louis Cardinals (55-55) at Petco Park this Saturday. The moneyline reflects St. Louis at +125, while San Diego stands at -145. The over/under for this game is set at 9. Scheduled starting pitchers include Michael McGreevy and Randy Vasquez.

MLB Predictions and Betting Odds for St. Louis Cardinals

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As a team, the Cardinals have recorded 195 doubles and hit 105 home runs this season. They are currently slugging .389, with 840 strikeouts and 346 walks. On average, the St. Louis Cardinals score 4.4 runs per game, ranking 14th in the MLB. They have accumulated 461 RBIs and 924 hits, posting a batting average of .250 and scoring 483 runs with a team OBP of .320.

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The Cardinals have a K/BB ratio of 2.78 and a combined WHIP of 1.28 from their pitching staff. They have allowed 104 home runs and a total of 492 runs (ranking 21st in MLB). With 961 hits (8.9 per 9 innings) and 451 earned runs, their earned run average stands at 4.17 (19th in the league), along with 800 strikeouts. Their pitchers issued 288 walks, contributing to a team FIP of 3.82 this season.

The bullpen has achieved a 65.0% save rate, appearing in 106 save situations. They have inherited 144 runners this season, with 31.9% scoring. The Cardinals’ relief pitchers have stepped in with runners on 106 times and handled 106 high-pressure situations. With a total of 329 pitchers used in relief, they’ve achieved 63 holds (13th in the league) and converted 26 of 40 save opportunities.

Defensively, the Cardinals have converted 69.4% of balls in play into outs through 8,754 innings, placing them 20th in MLB. They’ve totaled 2,918 putouts, 1,059 assists, and 45 errors. Their fielding percentage of .989 ranks 5th in professional baseball, along with 83 double plays turned.

Michael McGreevy has thrown 56 innings, racking up 37 strikeouts with a career ERA of 3.70 (23 ER allowed) and a WHIP of 1.036. He has allowed 51 hits (8.2 hits per nine innings) and issued 7 walks. McGreevy holds a 5-2 record in his career and a FIP of 3.64, having faced 224 batters in the majors.

The San Diego Padres have tallied 92 home runs and 417 RBIs this season. They boast 168 doubles, drawn 344 walks, and scored 445 runs with a team OBP of .318 and a batting average of .250. The Padres have a team slugging percentage of .380, averaging 4.08 runs per game (24th in MLB). They have struck out 767 times (28th in MLB) with 911 hits recorded.

This season, the Padres have a WHIP of 1.216 and a staff FIP of 3.86, leading the league in total hits allowed at 812. Their pitching staff has surrendered 413 runs with a team ERA of 3.55 (379 earned runs). They have an impressive strikeout to walk ratio of 8.60 (921 strikeouts vs. 358 walks), allowing 106 home runs and yielding 3.86 runs per 9 innings (3rd in the league).

In save opportunities, the Padres’ bullpen pitchers have participated in 49 chances, successfully converting 36 saves. They rank 2nd in MLB with a save percentage of 73.5%, having fielded 382 relievers this season. Their relief pitchers have entered 156 high-stakes situations and 129 with inherited runners. They maintain an inherited score percentage of 28.7% from 181 inherited base runners. With 127 save situations, the Padres have secure 75 holds and suffered 13 blown saves.

The Padres have completed 80 double plays with a .986 fielding percentage (13th in majors). They’ve accumulated 828 assists, 52 errors, and 2,886 putouts in this campaign. Their defensive efficiency rate stands at 71.5% over 8,658 innings played (3rd in professional baseball).

In his career, Randy Vasquez has allowed 243 hits while recording 147 strikeouts across 238 innings pitched. He has given up 107 earned runs, sporting a WHIP of 1.418 and a FIP of 4.0. He has a strikeout to walk ratio of 1.55, facing 1,045 opposing batters in his career. Vasquez holds a career record of 9-13 with an ERA of 4.04 and allows 9.2 hits per nine innings.

Who will emerge victorious in tonight’s MLB matchup against the spread or moneyline?

Tony Sink’s Prediction: Back San Diego (-145)

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