Matchup: Syracuse Orange vs. Clemson Tigers
Date: Saturday, September 20, 2025
Venue: Memorial Stadium, Clemson, SC
Broadcast: ESPN
Betting Odds: Tigers favored by 17.0 points
Over/Under Total: 55.5
On Saturday, September 20, 2025, Memorial Stadium will host the clash between the Clemson Tigers (1-2) and the Syracuse Orange (2-1), with Syracuse entering the game as 17.0-point underdogs. The anticipated total for the game is set at 55.5.
The Syracuse Orange are arriving at this matchup with a 2-1 record for the season. In their most recent game, they secured a dominant victory against the Colgate Raiders, ending with a score of 66-24. Defensively, the Orange allowed 107 rushing yards on 29 carries, averaging 3.7 yards per attempt. In the air, they allowed 30 completions on 54 attempts for a total of 301 yards, yielding a 55.6% completion rate. Overall, Syracuse executed 72 plays, racking up 620 total yards. On the ground, they completed 35 rushes for 173 yards, averaging 4.9 yards per carry.

Throughout the season, the Orange have accumulated a total of 1,458 yards. When it comes to scoring, they have achieved 9 passing touchdowns and 7 rushing touchdowns, with 6 turnovers so far. Syracuse has collected 80 first downs and faced 14 penalties totaling 123 yards. Their rushing attack averages 107.0 yards per game, ranking 123rd nationally. In terms of scoring prowess, the Syracuse Orange average 39.7 points per game.
Defensively, Syracuse ranks 109th in the nation in points allowed, giving up 29.7 points per game. Opposing teams are rushing for an average of 4.8 yards per carry and 165.0 yards per game this season, summing up to 495 rushing yards conceded over 3 games. In the passing department, the Orange have surrendered 822 yards, putting them 120th in the FBS, with 274.0 passing yards allowed per game and a completion percentage against of 56.4%. Overall, they are giving up an average of 439.0 yards per game, placing them 122nd in Division 1, allowing 6 passing and 4 rushing touchdowns.
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The Clemson Tigers are entering this game with a 1-2 record. Their last outing resulted in a heartbreaking defeat against the Georgia Tech Yellow Jackets, concluding at 24-21. Clemson managed to rush for an average of 5.0 yards per carry, accruing 174 yards on 35 attempts. The Tigers tallied 381 total yards with 61 plays, averaging 6.2 yards per play. In terms of pass defense, they allowed a completion percentage of 71.4%, yielding 211 yards on 20 of 28 passes, while conceding 147 rushing yards on 42 attempts at 3.5 yards per carry.

Scoring-wise, Clemson ranks 112th nationally, averaging 19.3 points per game, while their offense generates 319.3 yards per contest, ranking them 111th in Division 1. The Tigers have accumulated 112 penalty yards through 11 infractions, positioning them 121st in Division 1 concerning errors. They have thrown 3 interceptions and fumbled the ball twice, accumulating 47 first downs. This season, Clemson has registered 633 passing yards, averaging 211.0 passing yards per game, which gives them an 81st place in Division 1. Their rushing game averages 108.3 yards per outing and totals 325 rushing yards.
On defense, the Tigers allow 19.0 points per game, ranking them 54th in Division 1. They have given up 333 rushing yards (111.0 yards per game) and 3 rushing touchdowns this season. In the passing game, they’ve allowed 2 touchdowns and an average of 227.3 passing yards per game, positioning them 94th nationally. Clemson’s defense has participated in 203 plays, ranking them 91st in the nation. So far, their defense has recovered 2 fumbles and secured 3 interceptions, giving up a total of 57 points.
Who will emerge victorious in tonight’s Orange vs. Tigers matchup against the spread?
Parlays Pundit’s Prediction: Bet on the Tigers -17.0
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