- Matchup: Tennessee Titans vs Arizona Cardinals
- Date: Sunday, October 5, 2025
- Venue: State Farm Stadium, Glendale, AZ
- Broadcast: CBS
- Point Spread: Cardinals favored by 8.5 points
- Total Points Over/Under: 41.5
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The Arizona Cardinals (2-2) are set to host the struggling Tennessee Titans (0-4) at State Farm Stadium this Sunday. The Cardinals are currently 8.5-point favorites according to the latest betting lines. The over/under for the total points in the game is established at 41.5.
The Tennessee Titans enter this matchup with a disappointing record of 0-4 this season. In their previous game against the Houston Texans, they suffered a heavy defeat, finishing 26-0. Quarterback Cam Ward completed 10 of 26 passes for 108 yards, posting a quarterback rating of 35.4, along with one interception. Running back Tony Pollard recorded an average of 4.0 yards on 3 receptions, totaling 12 yards. Pollard also led the ground game for the Titans, with 14 carries for 64 yards, averaging 4.6 yards per carry. The Titans managed just 44 offensive plays, compiling a total of 175 yards. They showcased a commitment to the running game with 18 attempts, converting for 82 yards, averaging 4.6 yards per attempt. In terms of defense, Tennessee allowed their opponents to gain 129 yards on 35 rush attempts, averaging 3.7 yards per carry, and conceded 22 completions on 28 attempts for 224 yards, yielding a completion rate of 78.6%.
This season, the Titans have accumulated a total of 842 yards. As a team, they have registered 31 first downs and been penalized 35 times for a total of 296 yards. On offense, Tennessee has breached the end zone three times, accumulating 2 passing touchdowns and 1 rushing score. However, they have also turned the ball over five times, split between 2 interceptions and 3 fumbles. The rushing game has averaged only 87.0 yards per game, placing them 29th in the league. In scoring, the Titans rank low with an average of just 12.8 points per game.
<pDefensively, the Titans are ranked 29th in allowing points, giving up an average of 30.0 per game. They have been porous in the running game, allowing 4.8 yards per carry and 141.5 rushing yards per game. In terms of passing, they’ve surrendered 908 yards, placing them 22nd in the league. Tennessee allows an average of 227.0 yards through the air with a completion percentage against of 69.8%. Overall, they are allowing 368.5 total yards per game, ranking 25th in professional football. The Titans have conceded 6 passing touchdowns and 7 rushing touchdowns, giving up a significant total of 566 rushing yards through their first four games this season.The Arizona Cardinals currently sit at 2-2 for the season. In their last outing, they were narrowly defeated by the Seattle Seahawks, ending with a score of 23-20. Quarterback Kyler Murray tossed two touchdown passes and threw for 200 yards on 27 of 41 attempts, recording a quarterback rating of 73.2, but also threw two interceptions with an average of 4.9 yards per attempt. Running back Trey Benson carried the ball 8 times for 35 yards, averaging 4.4 yards per attempt. The top receiver for Arizona was Trey McBride, who caught 7 passes for 52 yards (an average of 7.4 yards per catch). The Cardinals had a successful running game as well, averaging 5.2 yards per carry, for a total of 89 yards from 17 attempts. They finished with 253 yards on 58 plays, averaging 4.4 yards per play. However, their pass defense struggled, allowing a completion percentage of 69.2% and yielding 229 yards on 18 of 26 attempts. Arizona’s defense also allowed 155 rushing yards on 35 carries, averaging 4.4 yards per run.
The Arizona Cardinals average 270.5 total yards per game, placing them 28th in the league. They accumulate an average of 105.8 rushing yards per game, with a running total of 423 yards this season. The offense has thrown 3 interceptions while recovering from losing no fumbles, achieving 42 first downs so far. Their offensive penalties have resulted in 226 total yards, marking them 9th in the league for defensive infractions. The Cardinals’ passing game has totaled only 659 yards, averaging 164.8 yards per game, placing them 28th in this category. Scoring-wise, they rank 22nd in the league, averaging 20.5 points per game.
On defense, the Cardinals have allowed 5 passing touchdowns, giving up an average of 255.5 yards through the air, putting them at 28th in the league. They have given up 384 rushing yards (96.0 per game), with 2 rushing touchdowns this year. The defense has secured 4 takeaways (2 fumbles forced and 2 interceptions). In total, they have allowed 74 points, ranking them at 30th in the NFL with just 272 plays processed from scrimmage. The Cardinals’ defense is allowing an average of 18.5 points per game, which is 6th best in the league.
Who do you think will prevail in this Titans-Cardinals game against the spread?
Prediction: Take the Titans +8.5
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