Tennessee Titans vs Houston Texans Prediction for 9/28/2025 NFL Picks, Top Bets & Odds in Week 4

Home » Tennessee Titans vs Houston Texans Prediction for 9/28/2025 NFL Picks, Top Bets & Odds in Week 4
  • Matchup: Tennessee Titans vs Houston Texans
  • Date: Sunday, September 28, 2025
  • Venue: NRG Stadium, Houston, TX
  • Broadcast: CBS
  • Betting Lines: Texans favored by 7 points
  • Total Points: Over/Under set at 39

This page may include affiliate links at no extra cost to you, thanks for your support.

The Tennessee Titans, currently winless at 0-3, will visit NRG Stadium this Sunday to challenge the Houston Texans, who also hold an 0-3 record. The Texans enter as 7-point favorites, while the total points for the game is projected at 39.

The Titans are struggling this season with an overall record of 0-3. In their most recent match against the Indianapolis Colts, they suffered a significant defeat, losing 41-20. Tony Pollard led the ground game for Tennessee, rushing 16 times for 45 yards (averaging 2.8 yards per carry). Chigoziem Okonkwo showcased a solid performance in receiving with 5 catches for 66 yards, averaging 13.2 yards per reception. Quarterback Cam Ward completed 23 of 38 passes for 219 yards and 1 touchdown, finishing with a quarterback rating of 74.3, along with 1 interception. The Titans’ defense allowed 137 rushing yards on 28 attempts, averaging 4.9 yards per carry. They also allowed 18 completions on 25 passing attempts, totaling 228 yards with a 72% completion rate. Overall, Tennessee ran 61 plays for a total of 282 yards, and their rushing game recorded 86 yards on 23 carries, averaging 3.7 yards per attempt.

NFL predictions and betting odds for Titans vs Texans

In terms of scoring, the Titans are averaging only 17.0 points per game. They rank 28th in the NFL for rushing yards, averaging 88.7 per game. This season, they’ve accumulated a total of 667 yards and have achieved 26 first downs, alongside 31 penalties costing them 261 yards. The Titans have turned the ball over 4 times (1 interception and 3 fumbles lost). In terms of touchdowns, they have recorded 2 passing touchdowns and 1 rushing touchdown.

Defensively, the Titans have allowed 684 passing yards, ranking them 22nd in the league, giving up an average of 228.0 passing yards per game with a completion percentage of 67.3%. They have also allowed 437 rushing yards over the season, resulting in 10 total touchdowns (4 by passing and 6 by rushing). Collectively, their defense is conceding an average of 373.7 yards per game, placing them 27th in the league, while allowing 5.3 yards per rush and 145.7 rushing yards per game. The Titans currently sit at 30th in defensive efficiency, allowing 31.3 points per game.

The Texans, like their opponents, are also struggling this season with a record of 0-3. Their latest encounter ended in a 17-10 loss to the Jacksonville Jaguars. Quarterback C.J. Stroud threw for 204 yards on 25 completions from 38 attempts and managed 1 touchdown, finishing with a quarterback rating of 66.1 while also throwing 2 interceptions. Nico Collins stood out as the leading receiver, catching 8 passes for 104 yards (averaging 13.0 yards per catch). Running back Nick Chubb carried the ball 9 times for 38 yards, averaging 4.2 yards per carry. Overall, the Texans finished with 271 total yards, running 57 plays for an average of 4.8 yards per play. Houston rushed for 87 yards on 19 carries, averaging 4.6 yards per attempt and allowed 24 rush attempts for 86 yards (3.6 yards per carry). Their passing defense held opponents to a 50% completion rate, allowing 205 yards on 20 of 40 attempts.

When it comes to scoring, the Texans rank last in the league, averaging only 12.7 points per game. This season, they’ve accumulated 517 passing yards, averaging 172.3 yards per game, placing them 26th among NFL teams. Their rushing attack has produced an average of 95.0 yards per game for a total of 285 yards. The Texans rank 29th in total offensive yards, averaging 267.3 yards per game. They’ve committed 24 penalties resulting in 191 penalty yards, ranking 14th in the league for penalties. Houston has faced turnovers too, with 3 interceptions and 2 lost fumbles, while securing 22 first downs as a team.

Defensively, the Texans have allowed 3 touchdown passes and give up approximately 206.7 yards per game through the air, ranking 13th in passing defense. With a total of 327 rushing yards allowed (109.0 yards per game), they’ve surrendered 4 rushing touchdowns this season. Over the season, they have generated 2 turnovers (1 interception and 1 fumble). The Texans’ defense has participated in 195 plays from the line of scrimmage, placing them 25th in the NFL. They are allowing an average of 17.0 points per game, which ranks them 7th in professional football.

Who will emerge victorious in this Titans-Texans showdown against the spread?

Prediction: Take the Titans to cover +7

Some links on this page are affiliate links. If you sign up or make a purchase through them, we may earn a small commission always at no extra cost to you. Thanks for helping us keep this site running.

Pick: Tennessee Titans +7
Bet Now

Leave a Reply

Your email address will not be published. Required fields are marked *

New Bookmakers
Bet99

Proud Partner of the NHL + Excellent live betting

 

Betway

Widest Range of Betting Options + Robust in-play with streaming

BetMGM

Top-Rated Betting App in Ontario with Live streaming & Cash-out

Sports Interaction

Crafted for Canada’s Bettors. Best Odds For NHL, CFL & NFL

© 2025 BettingEdge.ca. All Rights Reserved. BettingEdge.ca is your trusted source for Canadian sportsbook reviews, betting tips, and responsible gaming resources. Must be 19+ to bet. Play responsibly.