UCLA Bruins vs Indiana Hoosiers Prediction for 10/25/2025 College Football Picks, Best Bets & Odds

Home » UCLA Bruins vs Indiana Hoosiers Prediction for 10/25/2025 College Football Picks, Best Bets & Odds

  • Matchup: UCLA Bruins vs Indiana Hoosiers
  • Scheduled Date: Saturday, October 25, 2025
  • Venue: Memorial Stadium, Bloomington, IN
  • Broadcast: FOX
  • Betting Odds: Hoosiers favored by 25.0 points
  • Over/Under Total: 54.5

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The Indiana Hoosiers (7-0) are set to face off against the UCLA Bruins (3-4) at Memorial Stadium on Saturday, October 25, 2025. Indiana stands as a 25.0-point favorite, with the game total set at 54.5.

The UCLA Bruins enter this matchup with a record of 3-4 this season. In their most recent game, they triumphed over the Maryland Terrapins with a score of 20-17. The Bruins successfully rushed for a total of 193 yards on 35 attempts, averaging 5.5 yards per carry. Over the course of 70 plays, they accumulated 414 yards. On defense, UCLA allowed 23 completions on 48 attempts for 210 yards, resulting in a completion rate of 47.9%. Against the run, they conceded 127 yards on 26 carries, averaging 4.9 yards per rush.

College Football Picks: Kwazi Gilmer, UCLA Bruins Predictions and Odds

In terms of scoring, the UCLA Bruins average 22.4 points per game. Their ground game averages 171.0 yards per contest, placing them 51st in Division 1. This season, UCLA has amassed a total of 2,552 yards, with 10 touchdowns through the air and 7 on the ground. They have achieved 137 first downs and committed 59 penalties totaling 515 yards. The Bruins have turned over the ball 7 times.

Defensively, UCLA has allowed 1,252 passing yards, ranking them 27th in Division 1, which translates to an average of 178.9 yards allowed per game and a 61.9% completion rate for opponents. Overall, the Bruins give up an average of 364.9 yards per game, placing them 69th nationally. They have surrendered 12 touchdowns through the air and another 12 on the ground, allowing an average of 5.1 yards per rush and 186.0 rushing yards per game. This season, they have given up a total of 1,302 rushing yards across 7 games, ranking 93rd in allowing points with 27.4 per game.

On the other side, the Indiana Hoosiers boast an impressive record of 7-0. In their last outing, they claimed a decisive victory against the Michigan State Spartans, finishing 38-13. The Hoosiers amassed 464 yards on 56 plays, averaging an impressive 8.3 yards per play. They rushed for 132 yards on 28 attempts, averaging 4.7 yards per carry. Defensively, Indiana permitted 24 rushing attempts for 74 yards, yielding 3.1 yards per rush, while their passing defense faced a high completion rate of 78.9%, allowing 293 yards on 30 of 38 passing attempts.

The Indiana Hoosiers are racking up an average of 497.3 yards per game, placing them 7th in national rankings. They have incurred 200 penalty yards from 28 violations, ranking them 128th nationwide in terms of aiding their opponents. Their rushing offense averages 226.0 yards per game, with a total of 1,582 yards this season. Indiana has thrown 2 interceptions and allowed one fumble recovery while achieving 187 first downs. Currently, they rank 5th in the nation for scoring, averaging 43.9 points per game. The Hoosiers have also accrued 1,899 passing yards this season, averaging 271.3 yards per game, securing them 31st place in Division 1.

Defensively, Indiana has conceded only 595 rushing yards (85.0 yards/game) and 3 rushing touchdowns this season. They have also allowed just 3 touchdowns through the air, yielding an average of 163.7 yards per game, quality enough for 15th in the nation. Overall, Indiana has given up 81 points this season, recovering 1 fumble and recording 9 interceptions. Their defense has taken the field for 389 plays, ranking them 8th nationally, and they limit opponents to an impressive average of 11.6 points per game, putting them 4th in the country.

Who will emerge victorious in this Bruins vs Hoosiers college football showdown against the spread?

Prediction: Opt for the Hoosiers -25.0

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Pick: Indiana Hoosiers -25.0
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