USC Trojans vs Notre Dame Fighting Irish Forecast, 10/18/2025 College Football Selections, Top Bets & Odds

Home » USC Trojans vs Notre Dame Fighting Irish Forecast, 10/18/2025 College Football Selections, Top Bets & Odds

  • Matchup: USC Trojans vs Notre Dame Fighting Irish
  • Date: Saturday, October 18, 2025
  • Venue: Notre Dame Stadium, Notre Dame, IN
  • Broadcast: NBC Peacock
  • Betting Odds: Fighting Irish favored by (-8.5)
  • Point Total: 61

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This Saturday, October 18, 2025, the USC Trojans (5-1) will face off against the Notre Dame Fighting Irish (4-2) at Notre Dame Stadium. The Trojans enter this game as 8.5-point underdogs according to bookmakers. The total points for the game have been set at 61.

The USC Trojans boast a favorable record of 5-1 this season. In their latest matchup, they triumphed over the Michigan Wolverines with a score of 31-13. On that day, USC executed 36 rushing plays, amassing 224 yards, translating to an impressive average of 6.2 yards per carry. Overall, they ran 68 plays resulting in a total of 489 yards. Defensively, the Trojans allowed 15 completions on 26 attempts, totaling 207 passing yards for a completion rate of 57.7%. Against the rush, they conceded 109 yards on 31 carries, averaging 3.5 yards per rush.

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As for scoring, the USC Trojans lead with an impressive average of 45.5 points per game. They rank 16th in the nation for rushing yards, pulling in an average of 226.5 yards per game. To date, USC has compiled a total of 3,314 yards this season, with 14 passing touchdowns and 19 rushing touchdowns. They also recorded 157 first downs while accumulating 44 penalties, totaling 423 yards lost. Additionally, they have turned the ball over 7 times this season.

In terms of pass defense, USC has given up 1,462 yards, placing them 101st nationally. They allow 243.7 passing yards per game, with a completion rate of 62.3%. Over the current season, the Trojans have conceded 352.2 total yards per game, ranking them 62nd. They have given up 13 touchdowns through the air and 3 on the ground. Their rushing defense averages 3.5 yards per carry, allowing 108.5 yards per game, with a total of 651 rushing yards allowed over 6 games, ranking them 51st in points allowed, conceding 21.3 points per game.

The Fighting Irish enter this game holding a 4-2 record this season. In their previous game, Notre Dame achieved a resounding victory against the NC State Wolfpack, finishing 36-7. They allowed just 51 yards on 28 rush attempts (averaging 1.8 yards per carry). Notre Dame’s passing defense allowed an impressive completion percentage of 58.1%, enabling 182 yards through the air on 18 out of 31 attempts. Overall, they tallied 485 yards in the game while executing 71 plays (averaging 6.8 yards per play). Notre Dame rushed for an average of 3.7 yards per carry, finishing with 143 yards on 39 carries.

On the offensive front, the Fighting Irish rank 14th nationally, averaging 40.0 points per game. Notre Dame showcases an impressive average of 465.5 total yards per game, putting them 21st in Division I. They have incurred 285 yards in penalties over 35 infractions, ranking 80th in the nation. With 3 interceptions and 3 fumbles lost, they have accrued 143 first downs this season. Notre Dame’s passing game has amassed a total of 1,757 yards, averaging 292.8 yards per game, which places them 19th in Division 1. Their ground game averages 172.7 yards per game, bringing their total rushing yards to 1,036.

Defensively, Notre Dame has surrendered 637 rushing yards (averaging 106.2 yards per game) and allowed 6 rushing touchdowns. They have also given up 8 passing touchdowns alongside 245.3 passing yards per game, ranking 104th in Division 1. Overall, the Fighting Irish have allowed a total of 125 points this season. With 1 fumble and 11 interceptions recorded, their defense has taken the field for 397 plays, ranking them 67th. Notre Dame allows 20.8 points per game, positioning them 47th nationally.

Which team will prevail in this essential matchup between the Trojans and Fighting Irish against the spread?

Prediction: Bet on the Trojans +8.5

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Pick: USC Trojans +8.5
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