Matchup: Vanderbilt Commodores vs South Carolina Gamecocks
Date: Saturday, September 13, 2025
Venue: Williams-Brice Stadium, Columbia, SC
Broadcast: SEC Network
Betting Odds: Gamecocks favored by 5.5 points
Total Points Over-Under: 47
This exciting clash at Williams-Brice Stadium features the South Carolina Gamecocks (1-0) taking on the Vanderbilt Commodores (2-0) on September 13, 2025. The Gamecocks enter this matchup as 5.5-point favorites, with the combined score set at 47 points.
The Vanderbilt Commodores currently boast a flawless 2-0 record this season. In their previous outing, they triumphed over the Virginia Tech Hokies with a decisive 44-20 victory. The Commodores demonstrated a strong ground game, rushing 37 times for a total of 262 yards, averaging an impressive 7.1 yards per carry. Overall, they executed 57 plays, accumulating 490 total yards. Defensively, Vanderbilt allowed 17 completions out of 29 attempts, yielding 134 passing yards at a 58.6% completion rate. Against the run, they conceded 114 yards on 31 attempts, averaging 3.7 yards per carry.

On the season, the Commodores have amassed a total of 971 yards. They have scored 6 touchdowns through the air and another 6 on the ground, while having turned the ball over twice. Vanderbilt has achieved 48 first downs and committed 18 penalties totaling 137 yards. Their rushing attack averages 231.5 yards per game, ranking them 27th in the nation. With a scoring average of 44.5 points per game, the Commodores are making a strong case offensively.
Defensively, Vanderbilt has surrendered 221 yards via the pass, placing them 15th nationally. They average allowing 110.5 passing yards per game with a 56.3% completion rate. In terms of run defense, they allow an average of 2.8 yards per carry and 81.0 yards per game, having given up a total of 162 rushing yards over two games. This places them 34th in Division I football, only allowing 11.5 points per game.
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The Gamecocks come into this game with a 1-0 record after their recent victory, finishing 38-10 against the South Carolina State Bulldogs. South Carolina registered 3.5 yards per carry, totaling 125 rushing yards on 36 carries, while completing 253 total yards on 56 plays, averaging 4.5 yards per play. Defensively, the Gamecocks gave up a completion rate of 64.3%, totaling 208 yards from 18 out of 28 passing attempts. On the ground, they allowed 62 yards from 34 rushes, averaging 1.8 yards per carry.
South Carolina averages 290.5 yards of total offense per game, placing them 118th in the nation. They have committed 99 penalty yards over 15 infractions, ranking 34th nationally in allowing their opponents extra opportunities. The Gamecocks average 122.0 rushing yards per game, with a season total of 244 yards and 32 first downs recorded. Offensively, they rank 57th in Division I, scoring 31.0 points per game. This year, they have thrown for a total of 337 yards, averaging 168.5 passing yards per game, placing them 106th in the country.
Defensively, South Carolina allows an average of 10.5 points per game, positioning them 26th in Division I. They’ve allowed a total of 177 rushing yards this season (88.5 yards per game) without allowing any rushing touchdowns. Through the air, they have given up 1 touchdown and allowed 214.5 yards per game—ranking 83rd in Division I. The Gamecocks’ defense has been active, accounting for 134 plays, which ranks 87th nationally, and they have registered 1 fumble and 2 interceptions this season.
Who will prevail in this contest between the Commodores and Gamecocks against the spread?
Expert Prediction: Bet on the Commodores +5.5
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