- Matchup: Kentucky Wildcats vs. Louisville Cardinals
- Date of Event: Saturday, November 29, 2025
- Venue: L&N Federal Credit Union Stadium, Louisville, KY
- Broadcast: ACC Network
- Betting Odds: Cardinals favored by 3.0 points
- Total Points Over/Under: 47
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The Louisville Cardinals (7-4) look to secure a victory against the Kentucky Wildcats (5-6) at L&N Federal Credit Union Stadium on Saturday, November 29, 2025. The Wildcats enter this game as 3.0-point underdogs according to betting lines. The set over/under stands at 47 points.
This season, the Kentucky Wildcats are 5-6. In their previous game, they suffered a defeat to the Vanderbilt Commodores, falling 45-17. During that matchup, the Wildcats rushed the ball 19 times, accumulating just 31 yards, averaging 1.6 yards per carry. They executed a total of 68 plays, producing 315 offensive yards. On the defensive side, Kentucky allowed 37 completions on 44 attempts, yielding 539 passing yards and a completion ratio of 84.1%. In terms of run defense, they permitted 65 yards on 25 carries, averaging 2.6 yards per run.
In the scoring department, the Wildcats average 25.1 points per game. Offensively, they manage about 148.2 rushing yards per game, ranking them 77th in college football. Kentucky has totaled 3,953 yards this season, with a touchdown distribution of 15 through the air and 19 on the ground. The team has achieved 227 first downs but has also encountered 54 penalties, losing 438 yards. They have turned the ball over 20 times.
Defensively, the Wildcats have allowed 2,697 passing yards, placing them 107th nationally. They give up an average of 245.2 passing yards per game along with a completion percentage of 62.1%. Overall, they concede an average of 368.2 yards per game, ranking 66th in college football. They have allowed a total of 13 passing touchdowns and 18 rushing touchdowns, permitting an average of 3.5 yards per carry and 123.0 rushing yards per game. To date, they have allowed 1,353 rushing yards over 11 games, ranking 71st in FBS with an average of 25.1 points allowed per game.
The Louisville Cardinals aim to improve their 7-4 record this season. In their most recent game, they fell to the SMU Mustangs with a score of 38-6. The Cardinals averaged 4.4 yards per carry, accumulating 128 yards on 29 rush attempts. Overall, they finished that game with 228 yards from 49 plays, averaging 4.7 yards per play. On defense, Louisville allowed a completion percentage of 78.9%, giving up 307 yards on 30 of 38 passes. They conceded 36 rushing attempts for 178 yards, averaging 4.9 yards per carry.
The Louisville Cardinals average 384.2 offensive yards per game, ranking them 70th in the Football Bowl Subdivision (FBS). Their offense has incurred 699 yards in penalties over 75 infractions, placing them 41st in NCAA regarding giveaway yards. They average 153.9 rushing yards per game, having achieved a total of 1,693 rushing yards. The team has thrown 9 interceptions and surrendered 7 fumbles while earning 209 first downs. Currently, the Cardinals rank 55th in Division 1, scoring an average of 29.2 points per game. To date, they have recorded 2,533 passing yards, averaging 230.3 yards per game, which positions them 67th in the country.
On defense, the Cardinals allow 23.0 points per game, placing them 54th in the nation. They have yielded 1,277 rushing yards (116.1 yards per game) and 12 rushing touchdowns this season. Additionally, they have allowed 14 passing touchdowns and 198.8 passing yards per game, ranking 39th in D-1. Their defense has faced 716 plays, positioning them 45th in the FBS. They have also accumulated 6 fumble recoveries and 12 interceptions over the season, conceding a total of 253 points.
Who will come out on top in tonight’s matchup between the Wildcats and Cardinals against the spread?
Tony’s Prediction: Bet on the Wildcats +3.0
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