Matchup: Chicago Cubs vs Chicago White Sox
Date: Friday, July 25, 2025
Venue: Rate Field, Chicago, IL
Broadcast: Chicago Sports Network
Betting Odds: Chicago Cubs (-275) | Chicago White Sox (+220)
On Friday, the Chicago White Sox (37-66) will host the Chicago Cubs (60-42) at Rate Field, aiming to secure a victory. The betting odds position the Cubs at -275, while the White Sox are listed at +220. The game’s over/under is set at 9 runs, with Shota Imanaga and Adrian Houser set to take the mound.

The Cubs have tallied 173 doubles and launched 152 home runs as a team this season. With a slugging percentage of .446, they’ve struck out 784 times while drawing walks 346 times. Currently, the Chicago Cubs are averaging 5.3 runs per game, which ranks them 2nd in the league. They have accrued 525 RBIs and logged 899 hits, maintaining a batting average of .256 alongside an on-base percentage of .324.
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Chicago’s strikeout-to-walk ratio stands at 2.81, with the pitching staff holding a collective WHIP of 1.22. The Cubs have allowed 128 home runs and 420 runs (12th in MLB). They’ve given up 841 hits (averaging 8.3 per 9 innings) and 390 earned runs. This season, the Cubs have a team ERA of 3.86 (13th in MLB), striking out 764 batters while issuing 272 walks, resulting in a team FIP of 4.25.
This season, the Cubs have deployed a total of 335 relief pitchers, who have inherited 96 base runners; 29.2% of those inherited runners have crossed home plate. So far, they’ve registered 24 saves out of 35 opportunities, equating to a save percentage of 68.6%. The bullpen has recorded 63 holds (10th in MLB), entering 101 save situations. Cubs relievers have faced base runners on 70 occasions and have participated in high-leverage situations 100 times this year.
Chicago has converted 71.4% of balls in play into outs over 8,187 innings, ranking them 3rd in the league for defensive efficiency. The Boston Red Sox have 2,729 putouts, 864 assists, and 42 errors this season, with a fielding percentage of .988, placing them 5th in the majors, having turned 83 double plays.
Imanaga has pitched 248 innings, recording 227 strikeouts in his career. With a career record of 22-6, he holds a FIP of 2.72 and has faced 985 batters in the major leagues. His earned run average is 2.76 (76 earned runs) with a WHIP of 0.992, allowing 201 hits (7.3 hits per 9 innings) along with 45 walks.
The Chicago White Sox, this season, have achieved an OBP of .298 with a batting average of .224. They rank 9th in the league with 881 strikeouts and have recorded a total of 756 hits. Chicago has hit 85 home runs and racked up 365 RBIs. They have a team slugging percentage of .354 and average 3.70 runs per game (27th in MLB) with 166 doubles, 340 walks, and 381 runs scored.
As a unit, the White Sox have a WHIP of 1.378 and a FIP of 4.45. They rank 19th in MLB for hits allowed, totaling 857; the pitching staff has conceded 453 runs this year, posting an ERA of 4.08 (406 earned runs). Their strikeout-to-walk ratio is 7.50 (751 strikeouts versus 378 walks), having allowed 109 home runs and an average of 4.55 runs per 9 innings (21st in the league).
Chicago’s relief pitchers have appeared in 29 save opportunities, achieving 13 saves, ranking them 30th in the league with a save success rate of 44.8%. So far, they have used 324 relief pitchers I this campaign. The bullpen has faced high-leverage situations 91 times and has allowed 29.4% of inherited runners to score from a total of 136 inherited. In 72 save opportunities, the White Sox have tallied 43 holds and encountered 16 blown saves.
Defensively, the White Sox have registered 88 double plays while holding a fielding percentage of .983 (25th in the majors). They have amassed 857 assists, 63 errors, and 2,690 putouts this season. Their overall defensive efficiency stands at 69.7% (16th in MLB) across 8,070 innings played.
In his professional career, Houser has given up 651 hits while recording 528 strikeouts over 670 innings pitched. He has allowed 298 earned runs, with a WHIP of 1.364 and a FIP of 3.9. His strikeout-to-walk ratio is 2.01, having faced 2,867 batters thus far. Houser holds a career win-loss record of 37-41 and has an earned run average of 4.00, allowing 8.7 hits per nine innings.
Which team will prevail in tonight’s MLB matchup against the spread or moneyline?
Guy Bruhn’s Prediction: Bet on Chicago White Sox (+220)
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