Los Angeles Dodgers vs San Francisco Giants Forecast, 4/21/2026 MLB Selections, Top Bets & Odds

Home » Los Angeles Dodgers vs San Francisco Giants Forecast, 4/21/2026 MLB Selections, Top Bets & Odds

  • Matchup: Los Angeles Dodgers vs San Francisco Giants
  • Date: Tuesday, April 21, 2026
  • Venue: Oracle Park, San Francisco, CA
  • Broadcast: NBC Bay Area
  • Betting Odds: Los Angeles (-128) San Francisco (+106)

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This matchup at Oracle Park features the San Francisco Giants (9-13) squaring off against the Los Angeles Dodgers (15-6) on Tuesday. The moneyline for the game places the Dodgers at -128, while the Giants stand at +106. The over/under is anticipated to be 8.5. Expected pitchers are Yoshinobu Yamamoto and Landen Roupp.

MLB Picks Max Muncy Los Angeles Dodgers Predictions Best Bet Odds

As a collective, the Los Angeles Dodgers are averaging 5.8 runs per game, ranking them 1st in Major League Baseball. They have totaled 121 runs, boasting a on-base percentage (OBP) of .363. The Dodgers have accumulated 34 doubles and launched 37 home runs this season. With 119 RBIs and 207 hits, their batting average stands at .289. Los Angeles holds a slugging percentage of .494 and has been struck out 181 times while drawing 80 walks.

The Dodgers hold an earned run average (ERA) of 3.44 this season, placing them 7th in the league, with their pitchers collectively striking out 178 batters. Dodgers’ hurlers have given up 17 home runs and 73 total runs (2nd in MLB). The pitching staff has issued 66 walks while maintaining a FIP of 3.58 for the season. Los Angeles has allowed 140 hits (6.8 per 9 innings) and 71 earned runs, generating a strikeout-to-walk ratio of 2.70 and a combined WHIP of 1.11.

The bullpen has seen action with runners on base 14 times and has had 23 high-leverage appearances. This season, the bullpen has secured 14 holds (12th in MLB) and holds a 60.0% save rate, appearing in 24 save situations. They’ve recorded 6 saves while failing in 4 out of 10 opportunities. The relief corps has inherited 24 base runners this season, with 29.2% resulting in earned runs. So far, the Dodgers have used 67 relievers.

Defensively, the Dodgers have converted 74.1% of balls in play to outs over 1,674 innings, ranking them 1st in MLB. The Los Angeles defense contributes 558 putouts, 180 assists, and 5 errors, achieving a .993 fielding percentage and 2nd overall in the league alongside 14 double plays.

Yamamoto has pitched 288 innings, striking out 327 batters in his career. With a record of 21-11, his FIP stands at 2.58. Across his MLB tenure, he has faced 1,147 batters, allowing 84 earned runs for an ERA of 2.62 and a career WHIP of 1.016. He’s conceded 209 hits (6.5 hits per 9 innings) alongside 84 walks.

The Giants, meanwhile, have a slugging percentage of .365 and are scoring an average of just 3.41 runs per game (28th in MLB). They have recorded 39 doubles, with 43 walks, totaling 75 runs on the season. San Francisco has hit 13 homers and accumulated 71 RBIs, but they’ve also struck out 170 times (27th in the league) with 190 hits. The Giants maintain a team OBP of .293 and a batting average of .251 this season.

The team’s WHIP sits at 1.323, with a FIP of 4.11 this season, ranking them 17th in total allowed hits with 174. The Giants’ pitchers have given up 96 runs (4.15 overall ERA, 90 earned runs) and have recorded a K/BB ratio of 9.00 with 195 strikeouts against 84 walks. They have yielded 24 home runs and allow 4.43 runs per 9 innings (14th in MLB).

Giants’ bullpen pitchers have a 30.3% inherited score percentage for the 33 inherited base runners. Their relief unit has been called upon in high leverage situations 9 times and with runners on base 21 times. They’ve encountered 16 save situations, boasting 10 holds and 3 blown saves. Currently, their save rate ranks 24th in MLB at 50.0%, having used 74 bullpen pitchers throughout the year.

Across 1,755 innings, the Giants’ defensive efficiency is 69.6% (20th in MLB). The team has turned 22 double plays, showing a .985 fielding percentage (16th in MLB), while recording 209 assists, 12 errors, and totaling 585 putouts this season.

During his career, Roupp has allowed 171 hits, striking out 173 batters across 179 innings. He’s given up 71 earned runs, with a WHIP of 1.390 and a FIP of 3.5. He has a K/BB ratio of 2.22 and has faced 783 batters, maintaining a career record of 11-10 with a 3.57 ERA, allowing 8.6 hits per 9 innings.

Which team will emerge victorious tonight against the spread or on the moneyline?

Recommended Pick: Bet on Los Angeles (-128)

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Pick: Los Angeles Dodgers (-128)
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