Milwaukee Brewers vs Detroit Tigers Analysis, 4/22/2026 MLB Predictions, Top Picks & Odds

Home » Milwaukee Brewers vs Detroit Tigers Analysis, 4/22/2026 MLB Predictions, Top Picks & Odds

  • Game: Milwaukee Brewers vs. Detroit Tigers
  • Date: Wednesday, April 22, 2026
  • Location: Comerica Park, Detroit, MI
  • Broadcast: Detroit SportsNet
  • Betting Odds: Milwaukee (-152) Detroit (+126)

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The Milwaukee Brewers (12-9) are set to face off against the Detroit Tigers (12-11) at Comerica Park on Wednesday. The moneyline for this matchup has Milwaukee listed at -152 and Detroit at +126, with an over/under set at 8 runs. The anticipated starting pitchers are Chad Patrick and Casey Mize.

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The Brewers boast a slugging percentage of .366, having struck out 178 times while drawing 109 walks. They have notched 101 RBIs and 161 hits this season, with a batting average of .232. Milwaukee has recorded 32 doubles and 19 home runs, accumulating 106 runs with an on-base percentage (OBP) of .339. As a team, the Brewers are averaging 5.1 runs per game, placing them 8th in Major League Baseball.

Milwaukee’s pitching staff has produced a team ERA of 3.85 this season, placing them 12th in the league, with 189 batters struck out. They have given up 18 home runs and allowed 87 runs overall (9th in MLB). The Brewers have handed out 80 walks, while their FIP stands at 3.77. They’ve surrendered 167 hits (8.0 per 9 innings) and 80 earned runs, holding a K/BB ratio of 2.36 and a WHIP of 1.32.

This season, the Brewers have utilized 73 relief pitchers. Their bullpen has inherited 34 runners, with 41.2% of those runners scoring. The bullpen achieved 14 holds throughout the season (14th in MLB) and has stepped up in high-leverage situations 25 times. They secured 8 saves, missing out on 4 of their 12 save opportunities, yielding a save percentage of 66.7% in 26 save situations.

The Brewers have converted 69.2% of balls put into play into outs, totaling 1,683 innings, which ranks them 21st in professional baseball. The Miami Marlins have tallied 561 putouts, 184 assists, and 8 errors this season. Their fielding percentage is .989, ranking 7th in MLB, with a total of 14 double plays executed.

Chad Patrick has pitched 138 innings throughout his career, accumulating 136 strikeouts. With a career record of 4-8, he carries a FIP of 3.14 and has faced 578 opposing hitters. His earned run average is 3.19, having allowed 49 earned runs with a WHIP of 1.266. He has yielded 128 hits (8.3 hits per nine innings) and issued 47 walks.

The Detroit Tigers exhibit a team slugging percentage of .381 and average 4.35 runs per game (16th in MLB). They have achieved 46 doubles, drawn 84 walks and scored 100 runs. Detroit has recorded 17 home runs and 96 RBIs this season, with 187 strikeouts (16th in the league) and 186 hits. Their on-base percentage stands at .326, with a team batting average of .245.

With a WHIP of 1.268 and a team FIP of 3.52 this season, the Tigers rank 5th in total hits conceded (167). The Detroit pitching staff has allowed a total of 83 runs this year, showcasing a team ERA of 3.42 (75 earned runs allowed). Their strikeout-to-walk ratio is at 8.30 (183 strikeouts against 83 walks), having given up 13 home runs and surrendering 3.79 runs per 9 innings (6th in MLB).

Detroit’s relievers have an inherited score percentage of 34.0% out of 47 inherited runners. Relief pitchers have taken the mound 17 times in high-leverage situations, and they have appeared with runners on base 28 times. With 18 save situations, the Tigers have accrued 9 holds and 2 blown saves, ranking 7th in MLB with a 75.0% save rate from 63 appearances this season.

The Tigers have turned 19 double plays and maintain a fielding percentage of .984 (20th in MLB). With a total of 185 assists, 13 errors, and 593 putouts this year, Detroit has achieved a defensive efficiency of 70.5% across 1,779 innings (14th in professional baseball).

Throughout his MLB career, Casey Mize has allowed 466 hits while racking up 390 strikeouts over 462 innings pitched. He has given up 212 earned runs and carries a WHIP of 1.285, together with a FIP of 4.1. Holding a strikeout-to-walk ratio of 3.05, Mize has faced 1,963 batters, with a win-loss record of 24-26 and an ERA of 4.13, allowing 9.1 hits per nine innings.

Will Milwaukee secure a victory tonight, either against the spread or the moneyline?

Prediction: Back Milwaukee (-152)

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Pick: Milwaukee Brewers (-152)
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