New York Yankees and Houston Astros Prediction for 4/25/2026 MLB Picks, Best Bets & Odds

Home » New York Yankees and Houston Astros Prediction for 4/25/2026 MLB Picks, Best Bets & Odds

  • Matchup: New York Yankees vs Houston Astros
  • Date: Saturday, April 25, 2026
  • Venue: Daikin Park, Houston, TX
  • Broadcast: Space City Home Network
  • Betting Odds: New York (-122) Houston (+102)

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This Saturday, Daikin Park will play host to an intriguing matchup between the Houston Astros (10-16) and New York Yankees (16-9). The betting line favors the Yankees at -122, while the Astros are positioned at +102. The total runs line is set at 8.5, with Ryan Weathers and Mike Burrows expected to take the mound as the starting pitchers.

MLB props picks Aaron Judge New York Yankees

The Yankees have registered 37 doubles and launched 35 home runs this season. With a slugging percentage of .408, they have been struck out 238 times while also earning 117 walks. Currently, the Yankees are averaging 4.9 runs per game, ranking 9th in Major League Baseball. In total, they’ve amassed 115 RBIs and 181 hits, leading to a .223 batting average. They have scored 122 runs and maintain an OBP of .322.

New York’s pitching staff boasts a league-leading earned run average of 3.07, having struck out 219 opponents this season. They’ve allowed 19 home runs and 85 runs overall, also ranking 2nd in the league. With 66 walks issued, the team’s FIP sits at 3.31 for the season. The Yankees have given up 181 hits (averaging 7.3 per 9 innings) and 76 earned runs, with a K/BB ratio of 3.32 and a total WHIP of 1.11.

A total of 78 relievers have taken the mound for the Yankees this year. Relief pitchers have inherited 39 runners, with 30.8% crossing home plate. They hold 10 holds, placing them 27th in MLB rankings. Yankees’ bullpen has faced 27 inherited runners and appeared in 28 high-pressure situations. They have recorded 7 saves but have failed to convert 5 out of 12 save opportunities, yielding a save percentage of 58.3% across 23 situations.

This season, the Yankees have tallied 668 putouts, 225 assists, and committed 13 errors, maintaining a .986 fielding percentage—ranking 14th in professional baseball. They’ve turned 15 double plays and converted 71.5% of balls in play into outs throughout 2,004 innings, placing them 6th in the league.

Starting pitcher Ryan Weathers has a career record of 13-25, with a FIP of 4.70. He has faced 1,328 batters in the majors, yielding 317 hits (9.2 hits per nine innings) and issuing 107 walks. With an earned run average of 4.78 (164 ERs allowed) and a WHIP of 1.372, Weathers has logged 309 innings and struck out 271 batters in his career.

The Astros have hit 31 home runs this season, driving in 129 RBIs. They have recorded 59 doubles, drawn 113 walks, and scored a total of 137 runs. The team has a .349 on-base percentage and a .259 batting average this year, along with a .434 slugging percentage. Houston averages 5.27 runs per game (ranking 5th in MLB) but has struck out 197 times, ranking 25th among teams with 229 hits recorded.

On the pitching side, the Astros have given up 150 runs this season, maintaining an ERA of 5.81 (146 earned runs). They have permitted 35 home runs and allowed 5.97 runs per nine innings, ranking 29th in the league. Their team WHIP stands at 1.632, with a FIP of 5.13. They maintain a strikeout-to-walk ratio of 9.70 (245 strikeouts against 141 walks) and rank 27th in total hits allowed, surrendering 228 hits so far.

In 19 save opportunities, the Astros have achieved 12 holds and experienced 1 blown save. They have successfully converted 6 out of 7 save chances and boast a 31.0% inherited scoring rate from 58 inherited runners. Houston’s relief pitchers have entered 22 high-leverage situations and 34 instances with base runners. They rank 2nd in the league with an 85.7% save percentage, having utilized 84 bullpen players this year.

The Houston Astros have executed 25 double plays, holding a fielding percentage of .990, which ranks 5th in Major League Baseball. They have gathered 187 assists, committed 9 errors, and achieved 679 putouts throughout the season. Their defensive efficiency in 2,037 innings played stands at 66.8%, placing them 29th among professional teams.

In his MLB career, Burrows has allowed 126 hits and struck out 124 batters over 125 innings. With a win-loss record of 4-7, he has an earned run average of 4.53, giving up 9.1 hits per nine innings. He has surrendered 63 earned runs and holds a WHIP of 1.349 with a FIP of 4.5. His strikeout-to-walk ratio currently sits at 2.88, having faced 538 total batters in his MLB tenure.

Who will emerge victorious in tonight’s MLB contest against the spread or moneyline?

Selection: Opt for New York (-122)

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Pick: New York Yankees (-122)
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