Clemson Tigers vs LSU Tigers Outlook, 9/5/2026 College Football Picks, Top Bets & Odds

Home » Clemson Tigers vs LSU Tigers Outlook, 9/5/2026 College Football Picks, Top Bets & Odds

  • Matchup: Clemson Tigers vs LSU Tigers
  • Event Date: Saturday, September 5, 2026
  • Venue: Tiger Stadium, Baton Rouge, LA
  • Broadcast: ESPN+
  • Betting Odds: LSU Tigers favored by 10.5 points
  • Total Points Line: 51

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On Saturday, September 5, 2026, the LSU Tigers (7-6 last season) will face off against the Clemson Tigers (also 7-6 last year) at Tiger Stadium. The oddsmakers have placed LSU as 10.5-point favorites, with the total points line set at 51.

The Clemson Tigers concluded their previous season with a 7-6 record. In their latest encounter, they suffered a defeat against the Penn State Nittany Lions, finishing 22-10. On defense, Clemson allowed 135 rushing yards on 41 attempts, averaging 3.3 yards per carry. In the passing game, they permitted 23 completions on 35 attempts for 262 yards, with a success rate of 65.7%. Overall, they executed 65 plays, accumulating 236 total yards. Offensively, Clemson rushed the ball 25 times for just 43 yards, averaging a mere 1.7 yards per attempt.

Clemson Tigers Predictions and Odds Analysis

Throughout the last campaign, Clemson totaled 5,099 yards, generating 22 passing touchdowns and 20 rushing touchdowns, while turning the ball over 16 times. The team secured 274 first downs overall and incurred 57 penalties for 547 yards. They posted an average of 124.5 rushing yards per game, placing them 105th nationally. In terms of scoring, Clemson averaged 27.2 points per game.

Defensively, Clemson ranked 31st in Division 1, allowing an average of 20.5 points per game. Opponents averaged 3.5 yards per carry and 105.5 rushing yards per game, totaling 1,372 rushing yards against them over the season. In the passing department, Clemson gave up 3,266 yards, ranking 125th in the nation, yielding 251.2 passing yards per game and allowing a completion rate of 60.8%. They conceded 356.7 total yards per game, placing them 55th nationally, with 18 passing touchdowns and 10 rushing touchdowns permitted.

LSU also wrapped up the previous year with a 7-6 record. In their final game, they fell to the Houston Cougars, with a score of 38-35. LSU managed to run for 3.2 yards per attempt, totaling 77 yards on 24 carries. They compiled 344 total yards on 50 plays, averaging 6.9 yards per play. In passing defense, LSU allowed a completion percentage of 75.0%, giving up 236 yards on 27 completions from 36 attempts. They faced 46 rushing attempts, yielding 201 yards at an average of 4.4 yards per carry.

Last season, the LSU Tigers averaged 333.5 yards per game, ranking them 111th in the nation. LSU’s offense racked up 771 penalty yards over 91 penalties, placing 30th in college football in that category. They averaged 104.0 rushing yards per game, with a total of 1,352 rushing yards. The team threw 7 interceptions, allowed 7 fumbles, and earned 244 first downs. In scoring, LSU ranked 103rd with an average of 22.8 points per game, totaling 2,984 passing yards and averaging 229.5 passing yards per game—ranked 63rd nationally.

On defense, LSU allowed 1,613 rushing yards (124.1 yards per game) and 16 rushing touchdowns last season. They permitted 14 passing touchdowns while allowing 204.6 yards per game, ranking them 42nd nationally. Overall, they conceded 257 points throughout the season, with their defense recovering 4 fumbles and securing 17 interceptions. The LSU defense participated in 848 plays, ranking 72nd in the country, allowing an average of 19.8 points per game—23rd in Division 1.

Who will emerge victorious in this Tigers vs. Tigers matchup on the spread?

Prediction: Bet on the Tigers +10.5

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Pick: Clemson Tigers +10.5
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