- Matchup: Chicago White Sox vs St. Louis Cardinals
- Date: Friday, September 11, 2026
- Venue: Busch Stadium, St. Louis, MO
- Broadcast: Cardinals.TV
- Betting Lines: Chicago -144, St. Louis +120
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On Friday, the St. Louis Cardinals (72-75) will face off against the Chicago White Sox (75-70) at Busch Stadium. The current betting odds favor the White Sox at -144, while the Cardinals hold a +120 line. The over/under for this matchup is set at 9 runs, with expected starters Luis Castillo and Matthew Liberatore taking the mound.
As of now, the Chicago White Sox are slugging at a rate of .407, having been struck out 1,327 times and drawing 520 walks. This season, they have accumulated 654 RBIs and recorded 1,150 hits, leading to a batting average of .236. The team has managed 231 doubles and launched 190 home runs, scoring a total of 685 runs and boasting an on-base percentage (OBP) of .319. The White Sox are averaging 4.7 runs per game, positioning them at 6th in the league.
Chicago’s pitching staff has a team ERA of 4.14 (14th in MLB) and has struck out 1,200 batters. They have allowed 163 home runs and given up 644 runs overall (12th in MLB). The White Sox pitchers have issued 520 walks, with a FIP of 4.28 this season. They’ve allowed 1,174 hits at a rate of 8.2 hits per 9 innings and 595 earned runs. Their K/BB ratio stands at 2.31, along with a collective WHIP of 1.31.
Chicago’s bullpen has a save percentage of 58.7%, having entered 121 save situations. They have secured 37 saves this year, but have also blown 26 out of 63 opportunities. The relievers have inherited 232 base runners, with 30.2% of those subsequently scoring. White Sox relief pitchers have been called upon with players on base 158 times and have made 142 high-leverage appearances. A total of 482 relievers have been utilized this season, contributing to 55 holds (29th in MLB).
Defensively, the White Sox have accumulated 3,876 putouts, 1,179 assists, and 73 errors, leading to a fielding percentage of .986—ranking them 16th in MLB. They have turned 99 double plays, successfully converting 70.4% of balls in play into outs over their 11,628 innings, placing them 12th in major league baseball.
Starting pitcher Castillo has made 1,436 career innings, recording 1,516 strikeouts. With a career record of 85-86, he has a FIP of 3.57 and has faced 5,948 batters in the major leagues. His ERA stands at 3.63 (579 earned runs), and he sports a WHIP of 1.188, surrendering 1,245 hits (7.8 hits per 9 innings) and recording 461 walks.
On the other side, the St. Louis Cardinals have tallied 156 home runs and 648 RBIs this season. They’ve hit 209 doubles while drawing 470 walks and scoring 668 runs. The Cardinals maintain an on-base percentage of .317 and a batting average of .243. Their slugging percentage (SLG%) is .385, resulting in an average of 4.54 runs per game (11th in the league). They have struck out 1,156 times (25th in MLB) and recorded 1,208 hits overall.
The Cardinals are experiencing a WHIP of 1.352 along with a FIP of 4.08. As a pitching staff, they have given up 1,269 hits (25th in MLB) and allowed 680 runs with an ERA of 4.31 (627 earned runs). They hold a K/BB ratio of 8.00 (1,160 strikeouts to 501 walks), having allowed 146 home runs and surrendering 4.67 runs per 9 innings (21st in MLB).
St. Louis ranks 18th in save percentage at 60.6% and has used 499 relievers this year. Their bullpen has stepped into high-pressure situations 182 times, including 151 times with runners on base. In 168 save chances, the Cardinals have achieved 93 holds with 28 blown saves. They have called on their bullpen 71 times in save situations, successfully converting 43 saves. However, their inherited runner scoring rate stands at 41.0% from 222 inherited runners.
With 11,787 innings played, the Cardinals have a defensive efficiency rating of 69.0% (25th in MLB). They’ve managed 141 double plays and hold a fielding percentage of .988 (5th in the majors), with a total of 3,929 putouts, 1,363 assists, and 63 errors so far this season.
Liberatore comes into this match with a career record of 21-38 and an ERA of 4.91, allowing 9.6 hits per nine innings. His K/BB ratio is 2.60, having faced 2,050 opposing hitters in his career. Liberatore has yielded 258 earned runs, maintaining a WHIP of 1.400 and a FIP of 4.8. Over his career, he has allowed 502 hits and has recorded 416 strikeouts in 473 innings of work.
Which team will claim victory in tonight’s MLB matchup, whether against the spread or moneyline?
Pick: Opt for St. Louis (+120)
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