- Game Preview: St. Louis Cardinals vs. Milwaukee Brewers
- Date: Saturday, September 26, 2026
- Venue: American Family Field, Milwaukee, WI
- Broadcast: Brewers.TV
- Odds/Point Spread: St. Louis (+106), Milwaukee (-128)
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The St. Louis Cardinals (77-82) will travel to American Family Field this Saturday to face off against the Milwaukee Brewers (100-59). The current odds feature St. Louis at +106 and Milwaukee at -128, with the total set at 8 runs. The starting pitchers are expected to be Quinn Mathews for the Cardinals and Dustin May for the Brewers.

As a collective unit, the St. Louis Cardinals are averaging 4.5 runs per game, placing them 13th in the league. With a total of 710 runs recorded, they maintain an on-base percentage (OBP) of .314. The Cardinals have hit 228 doubles and launched 162 home runs with 686 RBIs and 1,293 hits this season, achieving a batting average of .241. Their slugging percentage stands at .379, and they have recorded 1,271 strikeouts compared to 504 walks throughout the season.
St. Louis boasts a K/BB ratio of 2.27, while their pitching staff has a WHIP of 1.35. The Cardinals have allowed 156 home runs and a total of 732 runs (22nd in the league). With 1,363 hits (averaging 8.6 per 9 innings) and 669 earned runs allowed, their earned run average (ERA) is 4.24 (20th in MLB), with 1,256 strikeouts recorded. The pitching staff has issued 553 walks, with a FIP of 4.08 this season.
The Cardinals’ bullpen has a save rate of 60.5%, having entered 176 save situations. They have achieved 46 saves out of 76 opportunities, with 30 blown saves so far. The relievers inherited 241 runners, with 40.2% scoring. The bullpen has come into games with players on base 166 times and has made 198 high-leverage appearances. In total, 541 relief pitchers have been utilized this year, accumulating 96 holds, placing them 8th in the league.
Defensively, the Cardinals have converted 69.0% of balls in play into outs over 12,768 innings, ranking them 24th in MLB. They’ve made 4,256 putouts, 1,490 assists, and recorded 76 errors, achieving a fielding percentage of .987—10th in professional baseball—and have turned 150 double plays.
Quinn Mathews has pitched 44 innings, achieving 39 strikeouts in his career. With a career record of 2-3, he carries a FIP of 3.62 after facing 190 batters. His ERA is 3.67 (18 earned runs), with a WHIP of 1.383 and 43 hits allowed (8.8 hits per 9 innings) alongside 18 walks.
The Milwaukee Brewers are boasting a slugging percentage of .402, averaging 5.13 runs per game (2nd in MLB). They have compiled 273 doubles, 657 walks, and 815 runs this season, hitting 152 home runs and recording 771 RBIs. The team has struck out 1,361 times (11th in the league) and totals 1,392 hits, alongside an OBP of .340 and a batting average of .258.
Milwaukee’s pitching staff has a WHIP of 1.187 and FIP of 3.71 this season. They’re ranked 2nd in MLB for total hits allowed with 1,173. Their pitching unit has given up 608 runs, achieving a team ERA of 3.52 (555 earned runs). Their K/BB ratio stands at 9.60, with 1,509 strikeouts and 511 walks issued. They have allowed 166 home runs, giving up 3.86 runs per 9 innings (4th in the league).
With 159 save situations, the Brewers have 84 holds and 20 blown saves, with their bullpen pitchers called into action in 73 save chances, earning 53 saves. Milwaukee’s relief pitchers have a 37.6% inherited run scoring rate out of 186 inherited baserunners. They’ve pitched in high leverage situations 156 times, with 128 appearances involving runners on base. They rank 6th in the league for save percentage at 72.6%, utilizing 499 relief pitchers throughout the season.
In 12,777 innings, the Brewers have a defensive efficiency of 71.1% (8th in baseball). They’ve completed 117 double plays and maintain a fielding percentage of .987 (7th in pro baseball), accumulating 1,254 assists, 71 errors, and 4,259 putouts this season.
Dustin May has allowed 310 hits throughout his career, notching 330 strikeouts in 357 innings. With a career record of 21-22, he posts a 4.03 earned run average while surrendering 7.8 hits per 9 innings. His WHIP stands at 1.223, with a FIP of 4.00 and a K/BB ratio of 2.60 after facing 1,505 batters in his professional baseball career.
Who will emerge victorious in tonight’s MLB match, covering the spread or clinching the moneyline?
Pick: Go with St. Louis (+106)
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