- Matchup: Florida State Seminoles vs. Louisville Cardinals
- Event Date: Friday, October 9, 2026
- Venue: L&N Federal Credit Union Stadium, Louisville, KY
- Broadcast: ESPN
- Betting Line: Cardinals favored by 4.5 points
- Total Points Over/Under: 58.5
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The Louisville Cardinals, with a record of 2-3, are set to face the Florida State Seminoles, who stand at 3-2, at L&N Federal Credit Union Stadium on Friday, October 9, 2026. The Cardinals are favored by 4.5 points according to oddsmakers, while the total points are projected to be 58.5.
Entering this matchup, the Florida State Seminoles boast a 3-2 record this season. In their previous game against the Virginia Cavaliers, the Seminoles secured a dominant victory with a score of 38-7. Florida State executed 65 plays, accumulating 464 yards in total. The rushing attack was particularly effective, amassing 281 yards on 46 carries, averaging 6.1 yards per attempt. Defensively, the Seminoles allowed just 37 rushing yards on 40 attempts, an impressive average of 0.9 yards per rush. Through the air, they permitted 14 completions from 32 attempts for 168 yards, resulting in a completion rate of 43.8%.
In terms of scoring, the Florida State Seminoles average 33.2 points per game, while their ground attack has tallied an average of 194.0 yards per game, placing them 40th in NCAA Division 1. The Seminoles have racked up a total of 2,095 yards this season, consisting of 6 passing touchdowns and 15 rushing touchdowns. They’ve accumulated 99 first downs but have been penalized 33 times for 332 yards and committed 7 turnovers.
Defensively, Florida State ranks 56th in college football, allowing 21.6 points per game. They concede an average of 3.4 yards per rushing attempt and 119.2 rushing yards per game, totaling 596 rushing yards allowed over five games. However, their pass defense has struggled, ranking 125th with 1,328 passing yards against. They allow an average of 265.6 passing yards per game and a completion percentage of 60.8%, yielding a total of 9 touchdowns through the air and 4 rushing touchdowns.
The Louisville Cardinals enter this contest with a 2-3 record. In their last outing, they fell to the NC State Wolfpack by a close score of 31-28. Louisville gained 485 yards over 55 plays, averaging 8.8 yards per play. Their rushing game was strong, averaging 9.2 yards per carry with a total of 231 yards on 25 attempts. On defense, the Cardinals allowed 120 rushing yards on 43 attempts (2.8 yards per rush) and their secondary conceded a completion rate of 61.0%, surrendering 373 yards on 25 completions from 41 attempts.
The Louisville offense ranks 17th nationally, averaging 486.0 yards per game. They have incurred 412 yards in penalties over 39 infractions, which ranks 20th in aiding their opponents. The Cardinals average 198.6 rushing yards per game and have accumulated 993 rushing yards this season. They have recorded 117 first downs, while only throwing 1 interception and losing 3 fumbles. With an impressive scoring average of 38.6 points per game, they sit 22nd in the nation. Louisville’s passing game has also excelled, with 1,437 passing yards, averaging 287.4 yards per contest, ranking 25th overall.
Defensively, Louisville has allowed 781 rushing yards (156.2 per game) and 8 rushing touchdowns this season. They have also given up 8 touchdown passes, allowing 266.8 passing yards per game, positioning them at 130th in defense rankings. To date, they have conceded 146 total points, with 4 fumble recoveries and 4 interceptions. The Cardinals’ defense has participated in 365 plays, ranking 131st nationally, and they allow 29.2 points per game, placing them 113th overall.
Who will prevail in this college football showdown between the Seminoles and Cardinals?
Expert Prediction: Choose the Cardinals -4.5
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