Houston Texans vs Jacksonville Jaguars Week 3 Predictions, NFL Picks, Best Bets & Odds for 9/21/2025

Home » Houston Texans vs Jacksonville Jaguars Week 3 Predictions, NFL Picks, Best Bets & Odds for 9/21/2025
  • Matchup: Houston Texans vs Jacksonville Jaguars
  • Date: Sunday, September 21, 2025
  • Location: EverBank Stadium, Jacksonville, FL
  • Broadcast: CBS
  • Betting Odds: Jaguars (-1)
  • Total Points Over/Under: 44.5

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The Houston Texans (0-2) are traveling to EverBank Stadium this Sunday to face off against the Jacksonville Jaguars (1-1). The Jaguars are slight favorites, opening at -1 according to Vegas lines, with the over/under set at 44.5.

The Texans enter this game with a record of 0-2. In their previous matchup against the Tampa Bay Buccaneers, the Texans fell short, losing 20-19. Nick Chubb led the rushing attack, carrying the ball 12 times for 43 yards (3.6 yards per carry). Nico Collins was effective in the passing game, averaging 17.3 yards per reception, totaling 52 yards on 3 receptions. Quarterback C.J. Stroud completed 13 of 24 passes for 207 yards and 1 touchdown, achieving a QB rating of 97 without any interceptions. Defensively, the Texans gave up 169 rushing yards on 30 attempts, averaging 5.6 yards allowed per rush. They also allowed 25 completions on 38 attempts, yielding 191 passing yards and a completion percentage of 65.8%. Overall, the Texans ran 43 plays, accumulating a total of 266 yards. They managed to rush the ball 19 times for 84 yards, averaging 4.4 yards per carry.

NFL Predictions Jacksonville Jaguars Odds and Best Bets

In terms of scoring, teams in the AFC South hit an average of 14.0 points per game. The Texans are currently averaging 99.0 rushing yards, placing them 21st in the league. They have amassed a total of 531 yards this season, achieved 14 first downs, and faced 17 penalties totaling 125 yards. Houston has turned the ball over twice, with one interception and one fumble. Scoring-wise, the Texans have recorded 1 passing touchdown and 1 rushing touchdown so far.

Defensively, the Texans have given up a total of 415 passing yards, ranking them 17th in the NFL, allowing an average of 207.5 passing yards per game with a completion rate of 68.7%. They have yielded 241 rushing yards over 2 games, surrendering 3 passing touchdowns and 2 rushing touchdowns. Overall, their defense ranks 20th, giving up an average of 328.0 yards per game, allowing 4.4 yards per carry and 120.5 rushing yards per game. However, they are positioned 9th in opponent scoring, permitting 17.0 points per game.

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The Jacksonville Jaguars come into this game with a record of 1-1. In their last outing, they lost to the Cincinnati Bengals, 31-27. Travis Etienne carried the ball 14 times for 71 yards, averaging 5.1 yards per carry. Parker Washington led the receiving corps with 5 catches for 76 yards (15.2 yards per catch). Quarterback Trevor Lawrence recorded 3 touchdowns and finished with 271 yards, completing 24 of 42 passes, achieving a quarterback rating of 80.6 with 2 interceptions, while averaging 6.5 yards per attempt. On defense, the Jaguars conceded 17 rushes for 48 yards (2.8 yards per attempt). Their pass defense allowed a completion rate of 62.2%, giving up 302 yards on 28 of 45 attempts. Overall, the Jaguars managed 400 yards on 69 plays, averaging 5.8 yards per play while rushing for 5.1 yards per carry and totaling 139 rushing yards on 27 attempts.

In scoring efficiency, the Jaguars rank 7th in the league with an average of 26.5 points per game. They have accumulated 439 passing yards this season, averaging 219.5 passing yards per game, which ranks 14th in the NFL. Their rushing attack averages 169.5 yards per game, totaling 339 rushing yards. The Jaguars’ offense ranks 4th in the league, averaging 389.0 yards per game. However, they have incurred 148 yards in penalties over 17 infractions, placing them 7th in this category. Collectively, they have achieved 24 first downs.

Defensively, they have allowed 4 passing touchdowns and give up 222.0 passing yards per game, ranking 19th in the league. On the ground, they have relinquished 161 rushing yards (80.5 yards per game) and 1 rushing touchdown this season. The defense has forced 6 turnovers, allowing a total of 41 points. The Jaguars’ defense has been on the field for 126 plays, ranking them 20th in the league, and they allow 20.5 points per game, sitting at 15th in the NFL.

Who will emerge victorious in this Texans vs. Jaguars NFL matchup against the spread?

Expert Pick: Select the Jaguars -1

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Pick: Jacksonville Jaguars -1
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