- Matchup: Buffalo Bills vs Los Angeles Rams
- Date: Monday, October 12, 2026
- Venue: SoFi Stadium, Inglewood, CA
- Broadcast: ESPN
- Betting Odds: Bills +3.0
- Total Points: 54
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The Los Angeles Rams (2-2) are set to clash with the Buffalo Bills (3-1) at SoFi Stadium this Monday night. The Rams are favored by 3 points according to bookmakers, with an over/under of 54 points for the matchup.
Buffalo enters this game with a record of 3-1 this season. Their most recent outing against the New England Patriots resulted in a narrow loss, ending 29-26. Quarterback Josh Allen completed 23 of 33 passes for 253 yards and secured 1 touchdown, recording a quarterback rating of 89.6 along with 1 interception. James Cook led the Bills’ rushing efforts with 12 carries for 75 yards (6.3 yards per carry). Keon Coleman was a standout in the receiving game, averaging 19.3 yards per reception with 116 yards from 6 catches. The Bills attempted 20 runs for a total of 91 yards, averaging 4.6 yards per play. Overall, they ran 53 plays for a total of 340 yards. Defensively, Buffalo allowed 22 completions on 37 attempts for 262 yards, resulting in a completion rate of 59.5%. They also allowed 143 rushing yards on 35 carries, averaging 4.1 yards per attempt.

This season, the Bills have amassed 1,545 total yards and 46 first downs, though they’ve faced penalties totaling 250 yards from 30 infractions. In scoring terms, Buffalo has achieved 6 passing touchdowns and 10 rushing touchdowns. However, they’ve turned the ball over 7 times (3 interceptions and 4 fumbles). On the ground, they rank 5th in the league with an average of 139.0 rushing yards per game, posting an impressive 31.8 points per game on average.
Defensively, the Bills are currently 25th in the league for opponent scoring, allowing an average of 26.8 points per game. They concede 4.0 yards per rushing attempt and 116.0 rushing yards per game this season. Through the air, they’ve relinquished 1,025 yards, ranking them 27th in the league. Buffalo is allowing an average of 256.3 passing yards per game with a completion percentage of 63.9%. In total, they are giving up 372.3 yards per game, placing them 27th league-wide. They’ve surrendered 10 touchdown passes and 3 rushing touchdowns, totaling 464 rushing yards over their first four games.
The Rams enter this matchup with a record of 2-2. In their last game against the Philadelphia Eagles, they secured a victory with a score of 24-20. Quarterback Matthew Stafford threw for 317 yards, completing 32 of 51 attempts, achieving a quarterback rating of 63.9, albeit with 2 interceptions. Running back Kyren Williams handled the ball 16 times for 80 yards, averaging 5.0 yards per carry. Wide receiver Puka Nacua was a key target, catching 9 passes for 125 yards (13.9 yards per catch). The Rams’ ground game averaged 4.2 yards per carry, ending with 106 rushing yards on 25 attempts. Overall, L.A. managed 415 total yards on 76 plays, averaging 5.5 yards per play. Their pass defense limited opponents to a completion rate of 44.4%, allowing just 68 yards on 12 completions out of 27 attempts, while they allowed 27 rushing attempts for 104 yards (3.9 yards per rush).
This season, the Rams have averaged 417.0 yards per game, ranking them 2nd in the league. They average 126.8 rushing yards per game and have racked up a total of 507 rushing yards. With 6 interceptions and 2 lost fumbles, they have secured 56 offensive first downs. The Rams have committed 31 penalties this season, resulting in 284 total yards, ranking them 13th for penalties in the league. Their passing game has generated 1,161 yards, averaging 290.3 yards per game, which ranks 2nd overall. In terms of scoring, the Rams sit at 19th in the league, averaging 21.3 points per game.
The Rams’ defense has allowed 7 passing touchdowns and averages 145.5 passing yards allowed per game, ranking them 2nd in the NFL. They have permitted a total of 408 rushing yards (102.0 yards per game), giving up only 1 rushing touchdown so far this season. On the defensive side, they have created 3 turnovers, allowing 83 points so far. The Rams have participated in 237 plays, positioning them 7th in the league and yielding 20.8 points per game, placing them 10th overall.
Who will come out victorious in tonight’s Bills vs Rams matchup against the spread?
My Selection: Bet on the Bills +3.0
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