- Matchup: Denver Broncos vs Arizona Cardinals
- Date: Sunday, October 25, 2026
- Venue: State Farm Stadium, Glendale, AZ
- Broadcast: CBS
- Betting Odds: Cardinals +4.0
- Over/Under Total: 43.5
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The Denver Broncos (4-2) are traveling to State Farm Stadium on Sunday to face off against the Arizona Cardinals (2-4). The Cardinals are set as 4-point underdogs according to Vegas bookmakers. The total for the game is established at 43.5 points.
Boasting a 4-2 record so far this season, the Denver Broncos are looking to extend their winning streak following a narrow victory over the Seattle Seahawks, finishing at 17-14. Quarterback Bo Nix had a solid outing, completing 17 of 27 attempts for 107 passing yards, achieving a quarterback rating of 71.1 without any interceptions. Leading the run game, J.K. Dobbins had 17 carries for 41 yards, averaging 2.4 yards per attempt. RJ Harvey recorded 31 receiving yards on three catches, averaging an impressive 10.3 yards per reception. Collectively, the Broncos rushed 28 times, accumulating 74 yards and averaging just 2.6 yards per carry. Overall, they executed 55 plays, yielding a total of 168 yards. Defensively, the Broncos allowed 27 completions on 51 attempts for 240 passing yards, with a completion rate of 52.9%. On the ground, they conceded 113 yards on 26 carries, averaging 4.3 yards per rush.
This season, the Broncos have amassed a total of 1,513 yards. Denver’s offense has generated 50 first downs and accumulated 44 penalties for 269 yards. In terms of touchdowns, the Broncos have scored 6 through the air and 5 on the ground, while turning the ball over 6 times (3 interceptions and 3 fumbles). On average, they are producing 84.2 rushing yards per game, placing them 26th in the league. In scoring terms, the AFC team averages 19.0 points per game.
In total passing yards, the Broncos have given up 1,251 yards this season, ranking 14th in the league. They allow 208.5 passing yards per game with a completion percentage against of 56.5%. Altogether, they have surrendered 839 rushing yards across 6 games, allowing 7 passing touchdowns and 6 rushing touchdowns. Overall, they are permitting 348.3 total yards per game, placing them 22nd in the league. Opponents run for an average of 4.7 yards per carry and 139.8 rushing yards per game. Defensively, the Broncos rank 10th, allowing 20.8 points per game.
The Arizona Cardinals head into this contest with a 2-4 record this year. Their last game concluded with an 18-16 victory over the Los Angeles Rams. Quarterback Jacoby Brissett threw for 218 yards, completing 24 of 35 passes, and recorded a quarterback rating of 73.3, with 1 interception and an average of 6.2 yards per attempt. Trey McBride was a key target, securing 7 receptions for 53 yards (7.6 yards per catch). Running back Zonovan Knight had a notable game with 15 carries for 80 yards, averaging 5.3 yards per attempt. The Cardinals executed a total of 70 plays, gathering 338 yards (4.8 yards per play). On the ground, Arizona averaged 3.4 yards per carry, finishing with 120 yards on 35 attempts. In the defensive effort, they conceded 92 yards on 20 rushing attempts (4.6 yards per carry). The Cardinals’ secondary faced challenges, allowing a completion rate of 75.8% and giving up 194 yards on 25 of 33 passing.
In terms of scoring, the Cardinals currently rank 24th in the league, averaging 21.0 points per game. They have accumulated 1,266 passing yards this season, averaging 211.0 yards per game, good for 20th in the league. Rushing-wise, they average 96.3 yards per game, having totaled 578 rushing yards so far. Overall, the Cardinals average 307.3 total yards, placing them 23rd in the league. This season, they have committed 41 penalties, surrendering a total of 396 yards to opponents, ranking 20th for assisting rival teams. So far, they have recorded 6 interceptions and have not lost any fumbles, accumulating 78 first downs.
Defensively, the Cardinals are allowing 29.7 points per game, ranking 32nd in the NFL. They have permitted 16 passing touchdowns and allowed 229.7 passing yards per game, ranking 22nd in the league. On the ground, they have given up 725 rushing yards (120.8 yards per game) and 6 rushing touchdowns throughout the season. The defense has participated in 350 plays, ranking 8th in total defensive plays in the league. This year, they have generated 8 turnovers (5 forced fumbles and 3 interceptions) and have conceded a total of 178 points.
Can the Broncos manage a victory against the spread over the Cardinals in today’s NFL matchup?
Prediction: Opt for the Cardinals +4.0
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