Prediction for Kentucky Wildcats vs South Carolina Gamecocks on 9/27/2025: College Football Picks, Best Bets & Odds

Home » Prediction for Kentucky Wildcats vs South Carolina Gamecocks on 9/27/2025: College Football Picks, Best Bets & Odds
  • Matchup: Kentucky Wildcats vs South Carolina Gamecocks
  • Date: Saturday, September 27, 2025
  • Venue: Williams-Brice Stadium in Columbia, SC
  • Broadcast: SEC Network
  • Point Spread: Gamecocks favored by 6.5 points
  • Over/Under Total: 47 points

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On September 27, 2025, Williams-Brice Stadium will host an exciting clash between the South Carolina Gamecocks (2-2) and the Kentucky Wildcats (2-1). The Wildcats enter as 6.5-point underdogs, while the total for the game is set at 47 points.

The Kentucky Wildcats boast a 2-1 record this season. In their most recent matchup against the Eastern Michigan Eagles, they secured a decisive win with a score of 48-23. Totaling 67 offensive plays, Kentucky amassed 492 yards. The Wildcats demonstrated a robust ground game, running the ball 46 times and gaining 252 yards, averaging an impressive 5.5 yards per carry. On defense, they allowed 131 yards from 30 attempts, averaging 4.4 yards per rush. The Wildcats’ secondary conceded 25 completions on 43 passes for 330 yards, resulting in a completion percentage of 58.1%.

College Football Predictions Kentucky Wildcats South Carolina Gamecocks

For the season, the Wildcats have accumulated 1,156 total yards. They have scored a combined 9 touchdowns on the ground and 2 through the air, committing just 2 turnovers so far. With 60 first downs and 16 penalties resulting in 148 yards, Kentucky averages 214.7 rushing yards per game, positioning them 28th in Division 1. They are currently scoring an average of 31.7 points per game.

Defensively, the Wildcats have surrendered 835 passing yards, ranking 81st in Division 1, allowing 278.3 yards per game and a completion percentage of 56.9%. Overall, they concede an average of 415 yards per game, placing them 116th nationally. This season, they have allowed 2 passing touchdowns and 5 rushing touchdowns, with opposing teams averaging 3.8 yards per rush and 136.7 rushing yards per game, totaling 410 yards given up in three games. Their defensive performance stands at 72nd in the country, allowing 23.0 points per game.

As they prepare for this matchup, the Gamecocks stand at 2-2 this season. Their last outing ended in a 29-20 defeat against the Missouri Tigers. South Carolina finished the game with 293 yards of total offense on 50 plays (an average of 5.9 yards per play). Struggling in the running game, they ended with -9 rushing yards on 22 attempts, averaging -0.4 yards per carry. Defensively, they allowed the Tigers to rush 48 times for 285 yards (5.9 yards per carry). The Gamecocks’ secondary allowed 171 yards on 16 completions out of 27 attempts for a completion rate of 59.3%.

When it comes to scoring, South Carolina currently ranks 99th in college football, averaging 22.3 points per game. They generate an average of 300.5 yards per contest, which positions them 123rd nationwide. The offense has amassed 282 yards in penalties from 37 infractions, ranking 6th in Division 1. The Gamecocks have thrown 2 interceptions and lost 2 fumbles, while gaining 67 first downs. So far this season, they have thrown for 881 yards, averaging 220.3 yards per game, which is 77th in the nation. In terms of rushing, they are averaging 80.3 yards per game with a total of 321 yards.

On defense, South Carolina has allowed 608 rushing yards (152.0 per game) and 4 rushing touchdowns this season. In the passing game, they’ve given up 4 touchdown passes and an average of 194.3 yards per game, ranking 58th in Division 1 with a total of 81 points allowed. Additionally, they have recorded 1 fumble recovery and 4 interceptions, participating in 272 defensive plays, ranking 93rd in college football. The Gamecocks are giving up an average of 20.3 points per game, placing them 54th in Division 1.

Who will emerge victorious in this exciting matchup between the Wildcats and the Gamecocks?

Expert Prediction: Bet on the Gamecocks to cover -6.5

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Pick: South Carolina Gamecocks -6.5
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