UCLA Bruins vs Northwestern Wildcats Prediction for 9/27/2025 College Football Picks, Best Bets & Odds

Home » UCLA Bruins vs Northwestern Wildcats Prediction for 9/27/2025 College Football Picks, Best Bets & Odds
  • Matchup: UCLA Bruins vs Northwestern Wildcats
  • Date: Saturday, September 27, 2025
  • Venue: Martin Stadium, Evanston, IL
  • Broadcast: BTN
  • Betting Odds: Northwestern Wildcats (-6.5)
  • Over/Under Total: 45

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On Saturday, September 27, 2025, Martin Stadium will host a clash between the Northwestern Wildcats (1-2) and the UCLA Bruins (0-3). The Bruins enter this game as 6.5-point underdogs, with a total set at 45.

The UCLA Bruins are looking for their first win this season, currently holding an 0-3 record. In their most recent game, UCLA faced off against the New Mexico Lobos but fell short, ending the game with a score of 35-10. The Bruins rushed the ball 22 times for a total of 109 yards, averaging 5.0 yards per carry. They accumulated 326 yards overall on 56 plays. Defensively, UCLA allowed 12 completions on 17 attempts, totaling 152 passing yards with a completion rate of 70.6%. On the ground, UCLA’s defense struggled, giving up 298 yards on 46 attempts, averaging 6.5 yards per carry.

college football predictions UCLA Bruins Northwestern Wildcats

This season, the Bruins have amassed a total of 974 yards. When it comes to scoring, they have recorded 3 passing touchdowns and 1 rushing touchdown, but have also turned the ball over 4 times. The team has achieved 56 first downs and incurred 30 penalties totaling 275 yards. On the ground, they average 122.0 yards, placing them 105th in the nation. The Bruins’ scoring average is currently at 14.3 points per game.

Defensively, UCLA has conceded 561 passing yards, ranking them 25th in the nation, allowing an average of 187.0 yards through the air with a high completion percentage of 75.1%. Overall, they are yielding an average of 431.0 yards per game and rank 123rd nationally in total defense, giving up a staggering 36.0 points per game.

The Northwestern Wildcats enter this matchup with a 1-2 record. In their previous game, they faced the Oregon Ducks and suffered a defeat, finishing 34-14. The Wildcats rushed for an average of 4.8 yards per carry and totaled 178 rushing yards on 37 attempts. Overall, Northwestern tallied 313 yards from 59 plays, averaging 5.3 yards per play. Their secondary allowed a 73.1% completion rate, yielding 197 yards on 19 completions from 26 attempts. They also allowed 30 carries for 176 yards, averaging 5.9 yards per rush.

In terms of scoring, the Wildcats find themselves ranked 115th in Division 1 with an average of 19.7 points per game. Offensively, they average 358.7 yards per game, placing them 96th. The Wildcats’ penalties total 100 yards from 14 infractions, ranking 122nd in Division 1. They have thrown 6 interceptions, allowed opponents to recover 2 fumbles, and achieved 58 first downs. This season, Northwestern has garnered a total of 541 passing yards, averaging 180.3 yards per game, which ranks 111th nationally. Their rushing attack is also notable, averaging 178.3 yards, with a total of 535 rushing yards thus far.

Northwestern’s defense has given up 515 rushing yards this season, averaging 171.7 yards per game, while allowing 4 rushing touchdowns. In terms of passing defense, they’ve allowed 3 touchdowns and 153.0 yards per game, ranking 21st nationally. Altogether, they have conceded 64 points this season. Their defense has made no fumble recoveries and secured 2 interceptions. With 180 defensive plays this season, they rank 11th nationally in defensive activity, allowing 21.3 points per game, which ranks them 61st in the nation.

Who will emerge victorious in this matchup between the Bruins and Wildcats?

Prediction: Take the Bruins +6.5

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Pick: UCLA Bruins +6.5
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