Arizona Wildcats vs Houston Cougars Forecast, 10/18/2025 College Football Selections, Top Picks & Odds

Home » Arizona Wildcats vs Houston Cougars Forecast, 10/18/2025 College Football Selections, Top Picks & Odds

  • Matchup: Arizona Wildcats vs Houston Cougars
  • Scheduled Date: Saturday, October 18, 2025
  • Venue: TDECU Stadium, Houston, TX
  • Broadcast: FS1
  • Betting Odds: Cougars favored by 2.5 points
  • Total Points (Over/Under): 47.5

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This matchup at TDECU Stadium sees the Houston Cougars (5-1) facing the Arizona Wildcats (4-2) on Saturday, October 18, 2025. Arizona enters as 2.5-point underdogs, with the total set at 47.5 points.

The Arizona Wildcats have a 4-2 record this season. In their most recent game, they suffered a defeat to the BYU Cougars, ending 33-27. On defense, the Wildcats allowed 258 rushing yards on 51 attempts, averaging 5.1 yards per rush. Through the air, they conceded 12 completions for 172 yards on 29 attempts, resulting in a completion rate of 41.4%. The Wildcats executed 79 plays for a total of 383 yards and managed 164 rushing yards on 34 attempts, averaging 4.8 yards per carry.

college football predictions Arizona Wildcats vs. Houston Cougars

In terms of scoring, the Arizona Wildcats are averaging 32.2 points per game. The team has produced 147.2 rushing yards per game, ranking them 79th nationwide. Over the course of the season, they have accumulated 2,533 total yards. Offensively, Arizona has registered 15 touchdown passes and 7 rushing touchdowns. They have achieved 139 first downs while committing 34 penalties totaling 278 yards. The Wildcats have turned the ball over 8 times this season.

Defensively, Arizona has allowed 908 passing yards, placing them 10th in the nation. They enable 151.3 passing yards per game with a completion rate surrendered of 49.7%. Totaling 275.7 yards allowed per game, they rank 15th in Division 1. They have permitted 1 passing touchdown and 10 rushing touchdowns, with opponents averaging 3.5 yards per rush and 124.3 rushing yards per game. Overall, they have allowed 746 rushing yards in 6 games and rank 28th in Division 1, giving up an average of 18.5 points per game.

The Houston Cougars come into this contest with a 5-1 season record. In their last outing, they triumphed with a score of 39-17 over the Oklahoma State Cowboys. On defense, Houston conceded 31 rushing attempts for 45 yards, averaging just 1.5 yards per carry. Their secondary allowed a completion rate of 45.0%, giving up 180 yards on 9 of 20 passing. The Cougars finished with 485 total yards on 79 plays, averaging 6.1 yards per play. They rushed for 166 yards on 45 attempts, achieving 3.7 yards per carry.

The Houston Cougars average 378.3 yards per game, positioning them 75th in college football. This season, the Houston offense has accrued 307 yards from 35 penalties, ranking 81st for turnovers. They average 159.2 rushing yards each game, with a total of 955 rushing yards this season. They have thrown 3 interceptions and lost 1 fumble while earning 109 first downs. On the scoreboard, they stand at 66th in Division 1 with an average of 29.2 points per game. To date, the Cougars have posted 1,315 passing yards, averaging 219.2 passing yards per game, which ranks 77th nationwide.

Defensively, the Cougars allow 17.5 points per game, ranking 23rd in Division 1. They have surrendered 753 rushing yards this season (125.5 yards per game) and 7 rushing touchdowns. In the air, they have allowed 5 passing touchdowns and an average of 181.0 passing yards, placing them 29th in the nation. Houston’s defense has been part of 405 plays, ranking 77th in college football. They have recovered 2 fumbles and made 6 interceptions this year, with a total of 105 points allowed.

Who will emerge victorious in this Wildcats vs. Cougars college football showdown against the spread?

Expert Prediction: Take the Cougars -2.5

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Pick: Houston Cougars -2.5
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